U-M researchers have shed new light on the mechanisms by which stem cells permanently shed their identity to become new types of cells.
When scientists discover a new phenomenon, they often get to name it. For researchers who study the model system Drosophila melanogaster, or fruit flies, that means participating in a long tradition that is a hallmark of the field’s culture.
LSI scientists identified a molecular switch that triggers a stem cell’s progeny to commit to generating only differentiated cell types by giving up its “stemness.”
LSI researchers have illuminated steps of the molecular mechanism that increases the overall output of cells during normal brain development