Immunostaining of larval brains with and without overexpression of the protein Zelda
December 9, 2021

A team of scientists has identified a key player that drives both embryonic and neuronal stem cell fate, and demonstrated that this process must be precisely regulated to establish the developmental program in both embryo and neuronal tissues.

November 21, 2018

U-M researchers have shed new light on the mechanisms by which stem cells permanently shed their identity to become new types of cells.

July 10, 2018

When scientists discover a new phenomenon, they often get to name it. For researchers who study the model system Drosophila melanogaster, or fruit flies, that means participating in a long tradition that is a hallmark of the field’s culture.

Molecular illustration
February 17, 2017

LSI scientists identified a molecular switch that triggers a stem cell’s progeny to commit to generating only differentiated cell types by giving up its “stemness.”

Scientific graphic
October 27, 2014

LSI researchers have illuminated steps of the molecular mechanism that increases the overall output of cells during normal brain development