Our group works on understanding the central control of energy homeostasis. The laboratory concentrates on the central melanocortin system, a complex set of neural circuits they have demonstrated to regulate a variety of physiological processes important to energy storage.
The melanocortin system plays a critical role in the long-term regulation of body weight, and has profound implications for human health and disease — including in obesity and the wasting that occurs in cancer patients.
We investigate how the central nervous system regulates energy storage, and the role of these neural circuits in obesity, disease cachexia, and anorexia nervosa.
Our Research
Roger Cone, Ph.D.
Mary Sue Coleman Director & Research Professor, U-M Life Sciences Institute
Vice Provost and Director, U-M Biosciences Initiative
Professor, Department of Molecular & Integrative Physiology, U-M Medical School
Professor, Molecular, Cellular, and Developmental Biology, LSA