Research Highlight: Scientists determine how one protein helps ‘reopen’ closed-off genes to regulate stem cell development
A team of scientists has identified a key player that drives both embryonic and neuronal stem cell fate, and demonstrated that this process must be precisely regulated to establish the developmental program in both embryo and neuronal tissues.
U-M researchers have shed new light on the mechanisms by which stem cells permanently shed their identity to become new types of cells.
When scientists discover a new phenomenon, they often get to name it. For researchers who study the model system Drosophila melanogaster, or fruit flies, that means participating in a long tradition that is a hallmark of the field’s culture.
LSI scientists identified a molecular switch that triggers a stem cell’s progeny to commit to generating only differentiated cell types by giving up its “stemness.”
LSI researchers have illuminated steps of the molecular mechanism that increases the overall output of cells during normal brain development