Anna Mapp Lab

We use the tools of synthetic organic chemistry, biochemistry, and molecular biology to better understand how genes are regulated.

Our Research

The Mapp research group uses the tools of synthetic organic chemistry, biochemistry, and molecular biology to better understand how genes are regulated.

Projects in the group range from the development of new synthetic methods for preparing complex, optically active structures to manipulating genes in Saccharomyces cerevisiae (yeast) in order to identify key protein-protein interactions in gene activation.

Our group is multidisciplinary with students from the Medicinal Chemistry Program, Program in Chemical Biology, and the Department of Chemistry.

Lab Mission Statement

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We believe that it is only through the unified commitment to and active involvement of each member that a diverse and inclusive environment for all can be created.

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Anna Mapp, Ph.D.

Research Professor, U-M Life Sciences Institute
Associate Dean for Academic Programs and Initiatives, U-M Rackham Graduate School
Edwin Vedejs Collegiate Professor of Chemistry, U-M College of Literature, Science, and the Arts

Publication Highlights

X-linked inhibitor of apoptosis protein (XIAP) is a client of heat shock protein 70 (Hsp70) and a biomarker of its inhibition

Cesa LC, Shao H, Srinivasan SR, Tse E, Jain C, Zuiderweg ERP, Southworth DR, Mapp AK, Gestwicki JE, J Biol Chem (2018)

From Fuzzy to Function: The New Frontier of Protein-Protein Interactions

Pricer R, Gestwicki J, Mapp AK, Acc Chem Res (2017)

Room 4000
Life Sciences Institute
Mary Sue Coleman Hall
210 Washtenaw Avenue
Ann Arbor, MI 48109-2216

The Mapp Lab believes that it is only a diverse and inclusive multidisciplinary research culture that enables lab members to work to their highest potential, to advance our scientific objectives, and to develop the next generation of innovators, scientists, and leaders.