Michael Cianfrocco, Ph.D.
Research Assistant Professor, U-M Life Sciences Institute
Assistant Professor, Department of Biological Chemistry, U-M Medical School
The advent of a new generation of electron microscopes and direct electron detectors has realized the potential of single particle cryo-EM as a technique to generate high-resolution structures.
Calculating these structures requires high performance computing clusters, a scarce resource. To address this limitation and facilitate the spread of cryo-EM, we developed a publicly available ‘off-the-shelf’ computing environment on Amazon's elastic cloud computing infrastructure.