Daniel Klionsky Lab
We investigate how cells respond to stress conditions through autophagy, and the broader implications for human physiology and disease — including in cancer and neurodegenerative disorders.
The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress.
This process, called autophagy (literally "self-eating") is implicated in many aspects of human physiology and disease, including cancer, neurodegenerative conditions like Parkinson's and Alzheimer's diseases, cardiomyopathy, diabetes and other metabolic disorders.
