Our Research

The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, particularly in times of stress. This process of internal house-cleaning in the cell is called autophagy — literally self-eating — and it is now considered the second form of programmed cell death.

Autophagy, self-eating at the cellular level, is implicated in many aspects of human physiology and disease, including cancer, neurodegenerative conditions like Parkinson's and Alzheimer's and cardiomyopathy, an enlargement of the heart.