Our lab studies optogenetic technologies for protein detection and manipulation in living cells.
We are applying cutting-edge protein engineering methods, such as directed evolution, to improve the dynamic range and overall performance of light-sensitive proteins, and to harness them for detection and manipulation of important biochemical events. Our goal is to expand the optogenetics toolbox with widespread utility across multiple subfields of cell biology and neuroscience.
Wenjing Wang, Ph.D.
News
New LSI faculty member is shedding light on how neurons function
The LSI's newest faculty member will use her protein engineering prowess to develop tools that can advance research across the fields of neuroscience and cell biology.
Publication Highlights
Wang W, Wildes CP, Pattarabanjird T, Sanchez MI, Glober GF, Matthews GA, Tye KM, Ting AY, Nat. Biotechnol (2017)
Kim MW, Wang W, Sanchez MI, Coukos R, von Zastrow M, Ting AY, Elife (2017)
Wang W, Nossoni Z, Berbasova T, Watson CT, Yapici I, Lee KS, Vasileiou C, Geiger JH, Borhan B., Science (2012)