May 23, 2018

Scientists have determined how microscopic marine bacteria build a chemical compound that has important biological activity — using a chemical transformation rarely seen outside of the lab.

May 21, 2018

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism.

April 23, 2018

Researchers at the LSI are creating a legion of fruit flies to advance our understanding of Down syndrome, thanks to funding from the Klatskin-Sutker Discovery Fund.

April 11, 2018

Researchers have determined that so-called 'junk DNA' plays a crucial role in holding the genome together.

Melanie Ohi and Amanda Erwin at the microscope
April 6, 2018

The LSI will lead a four-day cryo-electron microscopy workshop in June to introduce participants to common image processing software packages.

LSI building
April 4, 2018

Follow the LSI on LinkedIn to stay up-to-date with news and network with current and former members of the LSI community.

March 26, 2018

A residency at the U-M Life Sciences Institute is helping one visiting scholar from Liberia build research capacity at his university.

 

March 26, 2018

Roger Cone is not only the director of the LSI — he is also a distinguished researcher with an active research program that thrives on diverse viewpoints and areas of expertise.

Peng Li
March 20, 2018

The LSI’s newest faculty member is studying how the brain controls rhythmic breathing — and how these same circuits might be recruited to help fight conditions such as sleep apnea and sudden infant death syndrome (SIDS). 

Structure of the HpiC1 Stigonemataceae cyclase
March 12, 2018

How one type of enzyme allows a microorganism to produce molecules with a wide range of potentially beneficial activities — from fighting insects to killing fungi.

C. Elegans on a petri dish
February 28, 2018

Cross-talk between tissues actively coordinates aging  in a common model organism.

 

fruit fly
February 13, 2018
In fruit flies, repeating genetic elements shrink with age but then expand in future generations, a resurgence that may help explain how some cells stay immortal. 
Alan Saltiel, Ph.D.
February 8, 2018

Former LSI Director Alan Saltiel and colleagues a identify a key player in the control of energy expenditure during both obesity and fasting.

February 2, 2018

A team of researchers has developed a new system to measure how fat cells can be activated to burn energy. 

January 31, 2018

Findings remove a barrier to developing potential therapies for cancer patients with poor prognoses.

brain illustration
January 11, 2018

New insights allowed researchers to ameliorate the effects of Huntington’s disease in a fruit fly model of the disease.

LSI building
December 31, 2017

A round-up of media stories about LSI research and researchers from 2017.

Amy Fraley explores an ecologically diverse sites within the Maria la Gorda reef system in Cuba
December 17, 2017

Graduate student Amy Fraley recently joined faculty member David Sherman on his latest expedition in Cuba, where strict barriers have prevented access for nearly 60 years.

December 14, 2017

A grant program that encourages trainees to take the lead and learn what others are doing in their labs

December 7, 2017

U-M has one of the top cryo-EM labs in the country — learn more about how this technology is revolutionizing biology and how U-M is using it to study things like neurodegenerative diseases and bacterial infections.  

Jun Wu
November 21, 2017

How a common holiday spice — cinnamon — might be enlisted in the fight against obesity

 

Shawn Xu
November 20, 2017

LSI faculty member Shawn Xu was among the newly elected fellows of the American Association for the Advancement of Science.

Colorful chemistry structure
November 13, 2017

How enzyme catalysts can overcome the flaws of an important synthetic chemical process 

November 9, 2017

Patients with Chronic Kidney Disease may benefit from a new collaboration between U-M and AstraZeneca, who have partnered to develop a new therapeutic strategy for treatment. 

November 8, 2017

A previously dismissed genetic mechanism may contribute to nicotine dependence.

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