
Former LSI Director Alan Saltiel and colleagues a identify a key player in the control of energy expenditure during both obesity and fasting.

A team of researchers has developed a new system to measure how fat cells can be activated to burn energy.

Findings remove a barrier to developing potential therapies for cancer patients with poor prognoses.

New insights allowed researchers to ameliorate the effects of Huntington’s disease in a fruit fly model of the disease.

A round-up of media stories about LSI research and researchers from 2017.

Graduate student Amy Fraley recently joined faculty member David Sherman on his latest expedition in Cuba, where strict barriers have prevented access for nearly 60 years.

A grant program that encourages trainees to take the lead and learn what others are doing in their labs

U-M has one of the top cryo-EM labs in the country — learn more about how this technology is revolutionizing biology and how U-M is using it to study things like neurodegenerative diseases and bacterial infections.

How a common holiday spice — cinnamon — might be enlisted in the fight against obesity

LSI faculty member Shawn Xu was among the newly elected fellows of the American Association for the Advancement of Science.

How enzyme catalysts can overcome the flaws of an important synthetic chemical process

Patients with Chronic Kidney Disease may benefit from a new collaboration between U-M and AstraZeneca, who have partnered to develop a new therapeutic strategy for treatment.

A previously dismissed genetic mechanism may contribute to nicotine dependence.

Scientists identify a key driver of the progression to the most harmful form of fatty liver disease.

Reserach led by LSI affiliate faculty member Russell Ryan provides new insights into how Notch drives the growth of B-cell cancers

Findings provide clues about how one protein utilizes RNA binding to get into the HIV cell and mutate the virus' DNA.

LSI faculty member Daniel J. Klionsky was recognized for consistently demonstrating outstanding achievements in research, teaching and mentoring, service and a variety of other activities.

Chilled proteins and 3-D images: The cryo-electron microscopy technology that just won a Nobel Prize
LSI faculty members Michael Cianfrocco and Melanie Ohi explain the technology that won the 2017 Nobel Prize for Chemistry.

How two U-M graduate students came to co-first author a high-impact paper and develop expertise in one of the hottest areas of biology.

In the last century, Michigan was a driving engine of America’s manufacturing economy. Today, programs like the Perrigo Undergraduate Fellowship at the LSI are helping to fuel a new knowledge-based economy in the state.

The LSI expands its scientific reach with the addition of an affiliate faculty role. Affiliate faculty members will have labs located at the LSI — where they will have an adjunct appointment in addition to a tenure-track appointment in another unit on campus.

The welcomes structural biologist Melanie Ohi, Ph.D., to its faculty.

Researchers have discovered how an unlikely protein promotes cell division, even when the cell is treated with drugs to halt the process

To help attract early-career researchers of exceptional promise, the University of Michigan is launching a new, multidisciplinary, postdoctoral research fellowship program: the Michigan Life Sciences Fellows.

A mutation underlying the most common genetic cause of early-onset obesity was thought to potentially protect patients from heart disease. New research shows otherwise.