Patients with Chronic Kidney Disease may benefit from a new collaboration between U-M and AstraZeneca, who have partnered to develop a new therapeutic strategy for treatment.
A previously dismissed genetic mechanism may contribute to nicotine dependence.
Scientists identify a key driver of the progression to the most harmful form of fatty liver disease.
Reserach led by LSI affiliate faculty member Russell Ryan provides new insights into how Notch drives the growth of B-cell cancers
Findings provide clues about how one protein utilizes RNA binding to get into the HIV cell and mutate the virus' DNA.
LSI faculty member Daniel J. Klionsky was recognized for consistently demonstrating outstanding achievements in research, teaching and mentoring, service and a variety of other activities.
Chilled proteins and 3-D images: The cryo-electron microscopy technology that just won a Nobel Prize
LSI faculty members Michael Cianfrocco and Melanie Ohi explain the technology that won the 2017 Nobel Prize for Chemistry.
How two U-M graduate students came to co-first author a high-impact paper and develop expertise in one of the hottest areas of biology.
In the last century, Michigan was a driving engine of America’s manufacturing economy. Today, programs like the Perrigo Undergraduate Fellowship at the LSI are helping to fuel a new knowledge-based economy in the state.
The LSI expands its scientific reach with the addition of an affiliate faculty role. Affiliate faculty members will have labs located at the LSI — where they will have an adjunct appointment in addition to a tenure-track appointment in another unit on campus.
The welcomes structural biologist Melanie Ohi, Ph.D., to its faculty.
Researchers have discovered how an unlikely protein promotes cell division, even when the cell is treated with drugs to halt the process
To help attract early-career researchers of exceptional promise, the University of Michigan is launching a new, multidisciplinary, postdoctoral research fellowship program: the Michigan Life Sciences Fellows.
A mutation underlying the most common genetic cause of early-onset obesity was thought to potentially protect patients from heart disease. New research shows otherwise.
This year’s annual symposium explores the galloping pace of discovery, bringing to campus five pioneers and innovators in different areas of bioscience technology and research.
Connectivity between reproductive cells — or germ cells — in males serves as a quality assurance mechanism by making clusters of cells more sensitive to damage.
How a network of proteins and long noncoding RNA work together to push fat cells into fat-burning mode
International research team reveals why some species of cetaceans evolved sleek, muscular bodies while others grow to massive sizes
Research sheds new light on long-lasting changes that painful stimuli can exert at the level of a neural circuit — changes that can have a powerful impact on behavior.
After 12 weeks of taking an anti-asthma drug, a subset of patients with type 2 diabetes showed a clinically significant reduction in blood glucose during a clinical trial.
A long-term collaboration reveals the critical role played by the RNA binding protein LARP1 for mTORC1-mediated translation of an important class of mRNAs, including those that encode ribosome proteins.
After a file cleanup unearthed a 1970s Tang commercial staring LSI Professor Emerita Rowena Matthews, we reached out to her for the backstory.
How a new type of rapid-response defense mechanism helps protect cells from environmental stress while giving slower, well-known protection systems time to act
New cryo-EM research reveals 3-D snapshots of how a key biological machine unfolds a ribbon of protein through its central channel.
Researchers have captured the first cryo-electron microscopy snapshots of a cellular target for Type 2 diabetes in action.