About Us

Advances in microscope technology and computing have paved the way for cryo-electron microscopy to move structural biology into a new era — allowing scientists to study the form and function of biological "machines" that are too large to study using X-ray crystallography.

The U-M Life Sciences Institute is home to a world-class cryo-EM laboratory, with state-of-the-art instruments and faculty specializing in this emerging field.


July 13, 2020
The Cryo-EM Facility has reopened on a limited basis. Our staff is available to assist with both internal and external projects.  Please reach out to cryoem-support@umich.edu with questions.
March 25, 2020
We are sad to announce that this year's Cryo-EM Workshop has unfortunately been cancelled to align with the University of Michigan's ongoing efforts to respond to the COVID-19 pandemic to encourage social distancing. We look forward to organizing a workshop in June 2021!
March 20, 2020
Based on direction from the University of Michigan leadership, the Cryo-EM facility will be closed for all imaging services and walk-in use effective Friday, March 20 at 5:00 pm. During this downtime, no microscopes will be available for use and scheduling will be taken offline in MICORES.
While our services that require in-lab work will be unavailable, the following services will still be available to continue support to researchers:

·  consultations and project planning
·  data processing
·  support letters
·  manuscript writing
·  services for COVID-19 research (if any)

November 27, 2019
The LSI cryo-EM suite will be closed for renovations from Dec. 2, 2019, through late-spring, 2020. The closure will affect the Tecnai T12, the Talos Arctica and the Titan Krios.
The Morgagni on the 6th floor of LSI and the Glacios in the Biological Sciences Building will remain available for use.