Graphic with scientific imagery and the the number 20 on a blue background. Text: Celebrating 20 years of impact
Annual Symposium
Monday, May 20, 2024 - 09:00:00am - Tuesday, May 21, 2024 - 04:00:00pm

Saltiel Life Sciences Symposium 2024: Celebrating 20 Years of Impact

Kahn Auditorium, Biomedical Science Research Building (BSRB)
Audience This is a public event.

On May 20 and 21, 2024, the LSI will host a special two-day Saltiel Life Sciences Symposium highlighting the impactful science and scientists that have emerged from the LSI’s first 20 years. 

Schedule

Day 1: Monday, May 20, 2024

  • 9:00 a.m. | Welcome 
    Mary Sue Coleman, Ph.D., President Emerita of the University of Michigan

  • 9:15 a.m. | Mary Sue and Kenneth Coleman Life Sciences Lecture: 
    Genetics of hemostasis — From bedside to bench and back again
    David Ginsburg, M.D., U-M Life Sciences Institute

  • 10:10 a.m. | Break

  • 10:25 a.m | Session 1: Biological mechanisms at the finest scale — Insights from structural biology 
    Session Chair: Janet Smith, Ph.D., U-M Life Sciences Institute

    • Chasing G protein-coupled receptors with electron microscopy
      Georgios Skiniotis, Ph.D., Stanford University

    • Adapter control mechanisms of the p97/VCP AAA+ unfoldase
      Dan Southworth, Ph.D., University of California, San Francisco

    • Structural consequences of receptor barcoding by GRK2 and GRK5
      John Tesmer, Ph.D., Purdue University

    • Insights into neurodegeneration by in situ cryo-ET
      Shyamal Mosalaganti, Ph.D., U-M Life Sciences Institute

    • Structural basis of mRNA translation initiation and its regulation in eukaryotes
      Jay Brito Querido, Ph.D., U-M Life Sciences Institute

  • 12:10 p.m. | LSI Alumni Talks — Structural Biology 
    Session Chair: Melanie Ohi, Ph.D., U-M Life Sciences Institute

    • Structural dynamics and specificity in RhoGEF signaling
      Jen Cash, Ph.D., University of California, Davis

    • Molecular mechanism of IgM
      Junyu Xiao, Ph.D., Peking University

  • 12:45 p.m. | Lunch and Poster Session (View poster titles and authors)

  • 2:15 p.m.| Session 2: Exploring the building blocks of life — Cell and developmental biology
    Session Chair: Chelsey Spriggs, Ph.D., U-M Life Sciences Institute

    • The hematopoietic stem cell niche: Implications for bone marrow transplantation and regeneration
      Sean Morrison, Ph.D., University of Texas Southwestern Medical Center

    • Satellite DNA divergence in speciation
      Yukiko Yamashita, Ph.D., Whitehead Institute, Massachusetts Institute of Technology

    • Neutrophil signaling during acute inflammation
      Carole Parent, Ph.D., U-M Life Sciences Institute

    • Why does receptor recycling between endosomes and the plasma membrane require multiple parallel pathways?
      Lois Weisman, Ph.D., U-M Life Sciences Institute

  • 3:40 p.m. | Break

  • 3:55 p.m. | The LSI at 20: Origin and Evolution of the Life Sciences Institute
    Moderator: Roger Cone, Ph.D., U-M Life Sciences Institute

    • Huda Akil, Ph.D., U-M Medical School

    • Liz Barry, J.D., Higher Education Consultant

    • Mary Sue Coleman, Ph.D., President Emerita of the University of Michigan
    • David Ginsburg, M.D., U-M Life Sciences Institute

    • Paul Meister, Liberty Lane Partners, LLC

    • Alan Saltiel, Ph.D., University of California, San Diego

    • David Walt, Ph.D., Wyss Institute at Harvard University, Brigham and Women’s Hospital

  • 4:50 p.m. | Day 1 Closing Remarks
    Roger D. Cone, Ph.D.

 

Day 2: May 21, 2024

  • 9:00 a.m. | Welcome 

  • 9:10 a.m. | Session 3: From cells to systems — The physiology of health and disease
    Session Chair: Jun Wu, Ph.D., U-M Life Sciences Institute

    • New functions of Notch signaling in B and T cell immunity
      Ivan Maillard, M.D., Ph.D., University of Pennsylvania

    • TREM2+ macrophages at the crossroads of metabolic liver disease and cancer
      Jiandie Lin, Ph.D., U-M Life Sciences Institute

    • A new mechanism in the regulation of energy homeostasis
      Roger Cone, Ph.D., U-M Life Sciences Institute

  • 10:15 a.m. | Break

  • 10:45 a.m. | LSI Alumni Talks — Physiology 
    Session Chair: Ken Inoki, M.D., Ph.D., U-M Life Sciences Institute

    • Scrambling in membrane balance and metabolic homeostasis
      Xiao-Wei Chen, Ph.D., Peking University

    • Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging
      Lijun Kang, Ph.D., Zhejiang University

    • Fishing for novel diagnostics and therapeutics for blood and cardiovascular disorders
      Jordan Shavit, M.D., Ph.D., U-M Medical School

  • 11:35 a.m. | Lunch Break

  • 12:30 p.m. | Session 4: Untangling the complexity of the nervous system — New frontiers in neuroscience 
    Session Chair: Cheng-Yu Lee, Ph.D., U-M Life Sciences Institute

    • Decoding neuronal diversity: Tracking molecular changes along lineage progression
      Tzumin Lee, M.D., Ph.D., U-M Life Sciences Institute

    • Neural control circuits of breathing patterns
      Peng Li, Ph.D., U-M Life Sciences Institute

    • Protein-based sensors and tools for studying neuromodulatory systems
      Wenjing Wang, Ph.D., U-M Life Sciences Institute

    • How do we sense the world? Lessons from the worm
      Shawn Xu, Ph.D., U-M Life Sciences Institute

  • 1:55 p.m.| Break 

  • 2:05 p.m. | Session 5: Catalyzing discovery — Innovation at the intersection of chemistry and biology
    Session Chair: Anna Mapp, Ph.D., U-M Life Sciences Institute

    • (I’m still trying to) Target protein stability to treat neurodegenerative diseases
      Jason Gestwicki, Ph.D., University of California, San Francisco

    • Making connections between protein sequence space and chemical space
      Alison Narayan, Ph.D., U-M Life Sciences Institute 

    • Discovery and engineering of natural product molecules for drug discovery
      David Sherman, Ph.D., U-M Life Sciences Institute 

    • Ultrasensitive single-molecule detection platforms for biomarker discovery and beyond
      Connie Wu, Ph.D., U-M Life Sciences Institute

  • 3:30 p.m. | Break

  • 3:40 p.m. | Session 6: Computation & Artificial Intelligence in Life Sciences
    Session Chair: Jun Li, Ph.D., U-M Medical School

    • Mathematical and computational studies in human population genetics
      Noah Rosenberg, Ph.D., Stanford University (video)

    • AI-based behavioral analysis for life sciences
      Bing Ye, Ph.D., U-M Life Sciences Institute (video)

    • Algorithms to automate cryo-EM data collection
      Mike Cianfrocco, Ph.D., U-M Life Sciences Institute

  • 4:40 p.m.| Closing Remarks