LSI Seminar Series: Liver macrophage biology in metabolic and cardiogenic liver disease
Macrophages play a critical role in liver homeostasis and in the response to injury. More recently, the heterogeneity of hepatic macrophage phenotypes and function have been recognized as key contributors to liver disease. This talk will highlight the changes in resident and recruited macrophages that occur in metabolic dysfunction steatohepatitis and in cardiogenic liver disease, with an emphasis on possible diagnostic and therapeutic implications.
Speaker
Joel Schilling is currently an associate professor of medicine and of pathology & immunology at Washington University School of Medicine. Schilling received his undergraduate degree in chemistry with honors from Colorado College. He then joined the medical scientist training program at Washington University, where he received his graduate degree in immunology in Scott Hultgren’s lab. Upon graduation he joined the internal medicine residency program as a part of Washington University's physician scientist training program. He subsequently completed his medical training in internal medicine, cardiology, and advanced heart failure and transplant.
Schilling has been a member of the faculty at Washington University school of medicine since 2009 and became medical director of the Heart Transplant Program in 2021. He also serves as the Cath Lab director for the Pulmonary Hypertension Program. His translational research program focuses on the cardiohepatic axis in metabolic disease and in heart failure. Within this framework, he has had an interest in diabetes, Group 2 PH, right heart failure and the liver immune system. He is the author of more than 120 manuscripts published in peer-reviewed journals and has an h-index of 46. He and his wife Denise have 4 boys. His favorite hobby in playing rock music in his band South of Sanity.