Bing Ye discusses labwork with postdoctoral researcher Elizabeth Cebul
March 19, 2021

As we marked our first “Panniversary,” LSI professor and research associate dean Bing Ye reflected on how the institute has navigated a year of reduced research efforts, and the potential long-term impacts — both good and bad — on the scientific enterprise.

Regions of the Drosophila central nervous system that are activated in response to noxious stimulation
October 14, 2020

Researchers have uncovered a neural network that enables Drosophila melanogaster to convert external stimuli of varying intensities into a “yes or no” decision about when to act.

July 10, 2018

When scientists discover a new phenomenon, they often get to name it. For researchers who study the model system Drosophila melanogaster, or fruit flies, that means participating in a long tradition that is a hallmark of the field’s culture.

April 23, 2018

Researchers at the LSI are creating a legion of fruit flies to advance our understanding of Down syndrome, thanks to funding from the Klatskin-Sutker Discovery Fund.

July 13, 2017

Research sheds new light on long-lasting changes that painful stimuli can exert at the level of a neural circuit — changes that can have a powerful impact on behavior.

Neuronal overgrowth in Down syndrome model
May 19, 2015

A class of FDA-approved cancer drugs may be able to prevent problems with brain cell development associated with disorders including Down syndrome and Fragile X syndrome.

Bing Ye
April 17, 2014

Researchers at U-M have shown that the specific connection of sensory neurons to the correct targets in the central nervous system in fruit flies is dependent on how active the neurons are.

Axons in development
June 5, 2013

U-M researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic approaches to an aspect of the syndrome.

Drawing of a neuron
June 4, 2013

LSI reseachers have evidence that a single gene controls both halves of nerve cells, and their research demonstrates the need to consider that design in the development of new treatments for regeneration of nerve cells.