Our Research

When stem cells divide, what determines which daughter cell will remain a stem cell and which will differentiate into another tissue type?

Our lab is probing this important question, and seeking to understand the mechanisms underlying asymmetric stem cell division. 

A balance between differentiated daughter cells and self-renewing stem cells is critical for life. An excess of self-renewal can lead to the development of cancer, while an excess of differentiation can deplete the stem cell pool necessary for long-term health.