May 13, 2020

Researchers have discovered how a protein that is overproduced by fat cells in an obese state may be contributing to the demise of two immune cell types — and driving further metabolic disorders in the process

Liver cells, illustration
August 8, 2019

Researchers have  created a high-resolution picture of the cells at work inside a key hub of metabolism — the liver — and how individual cell types are reprogrammed in disease.

January 14, 2019

Researchers have identified a hormone produced by the liver that tells the body to downshift its metabolism when it’s expending a lot of energy, revealing a potential target for treating metabolic disorders.

Jiandie Lin and Carole Parent
November 27, 2018

Fifteen researchers at the University of Michigan — including two from the Life Sciences Institute — have been named fellows of the American Association for the Advancement of Science, an honor bestowed upon AAAS members by their peers.

July 30, 2018

Scientists uncover a potential new role for long noncoding RNA in obesity and non-alcoholic fatty liver disease.

February 2, 2018

A team of researchers has developed a new system to measure how fat cells can be activated to burn energy. 

LSI building
December 31, 2017

A round-up of media stories about LSI research and researchers from 2017.

Colorful liver cells
November 6, 2017

Scientists identify a key driver of the progression to the most harmful form of fatty liver disease.

colorful fat cells
August 7, 2017

How a network of proteins and long noncoding RNA work together to push fat cells into fat-burning mode

May 4, 2017

An unexpected mechanism of glucose sensing in skeletal muscles contributes to the body’s overall regulation of blood sugar levels.

Junk food (cookelma / iStock / ThinkStock)
November 10, 2015

Identified: a pathway in the liver, controlled by a protein known as BAF60a, that contributes to the negative effects of a high-fat diet by stimulating the production of bile — which helps the body to absorb more cholesterol and other fats from the foods we eat.

colorful fat cells
November 17, 2014

LSI scientists have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders.