MC3R, AgRP and VGAT mRNA expression in the arcuate nucleus of a mouse brain
April 21, 2021

Scientists have identified a protein called the melanocortin 3 receptor as a potential drug target for treating obesity and eating disorders such as anorexia nervosa.

Artistic representation of a neural network
March 29, 2021

A new study from the University of Michigan offers insights into how neural circuitry in the brain operates and responds to feeding and hunger in real-time.

April 23, 2020

An international team of researchers has unveiled the precise shape of a key player in human metabolism, which could open the door to better treatments for obesity and other metabolic disorders.

Isin Cakir, Ph.D.
October 31, 2019

Research investigator Isin Cakir, Ph.D., has been awarded the the 2019 Klatskin-Sutker Discovery Fund award to develop a suite of new molecules targeting obesity.

Jonathan Nelson
February 15, 2019

LSI Outreach Awards recognize the value of our community members' efforts to connect research, teaching and service to the public

January 24, 2019

Four teams of graduate students and postdoctoral fellows will soon launch their own cross-lab, interdisciplinary projects, with funding from the LSI Cubed program.

August 21, 2018

Scientists revealed that a receptor protein in the brain acts as the body’s “energy rheostat,” ensuring that the balance of energy and fat does not drift too far above or below its homeostatic set point. The findings open new doors for developing anti-obesity drugs.

March 26, 2018

Roger Cone is not only the director of the LSI — he is also a distinguished researcher with an active research program that thrives on diverse viewpoints and areas of expertise.

LSI building
December 31, 2017

A round-up of media stories about LSI research and researchers from 2017.

August 22, 2017

A mutation underlying the most common genetic cause of early-onset obesity was  thought to potentially protect patients from heart disease. New research shows otherwise.

July 18, 2017

International research team reveals why some species of cetaceans evolved sleek, muscular bodies while others grow to massive sizes

Roger Cone
May 18, 2017

LSI Director Roger Cone named to an additional role as the university's first vice provost and director of the biosciences initiative.

Roger Cone
October 17, 2016

LSI Director Roger Cone is among the new members of the National Academy of Medicine of the National Academies, one of the highest honors in the fields of health and medicine.