Center for Chemical Genomics

We provide high-throughput screening of extensive small molecule, natural product and siRNA libraries for basic biology and drug discovery projects.

About Us

The Center for Chemical Genomics provides high-throughput screening of extensive small molecule, natural product and siRNA libraries — along with assay development and optimization — for basic biology and drug discovery projects.

Our dedicated staff has years of experience in academic drug discovery and within the pharmaceutical industry, allowing us to provide expert guidance to researchers through every stage of a project.

Our services are available to U-M researchers and to outside academic and industry partners.

If you're a new user, please visit our getting started guide.

Announcements

March 1, 2024

The cardiac ion channel hERG (KV11.1) represents one of the most common safety liabilities that can plague early-phase drug discovery projects. Various drugs can inhibit hERG, leading to long QT syndrome, a potentially fatal disorder. Therefore, testing for compound activity at hERG is a critical step in characterizing and prioritizing potential lead molecules.

The Center for Chemical Genomics is now offering hERG channel testing using SyncroPatch, a highly innovative high-throughput technology for measuring ion channel activity. Do not overlook this crucial step in your drug discovery project! Contact [email protected] for more information.

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Infographic depicting the hERG project workflow

Our Services

High-Throughput Screening

We offer high-throughput screening of extensive small molecule, natural product and siRNA libraries — along with assay development and optimization — for basic biology and drug discovery projects.

Sample Libraries

We have more than 250,000 diverse small molecule compounds, a unique library of more than 45,000 natural product extracts, an extensive siRNA library and a growing library of 7,000-plus FDA-approved drugs and clinical compounds for drug repurposing projects.