Ciria Hernandez working in the Center for Chemical Genomics
July 29, 2021

Two new research projects are moving forward at the U-M Life Sciences Institute, with support from philanthropic funds established specifically to high-risk, high-reward research.

Voices of the LSI
July 7, 2021

A quarterly column on the LSI’s work to cultivate a diverse, equitable and inclusive climate

June 30, 2021

Researchers have demonstrated that a natural compound produced by lichens can block the activity of a protein that is central to the gene-activation process. The research, conducted in human-derived breast cancer cells, points to this protein as potential therapeutic target.

MC3R, AgRP and VGAT mRNA expression in the arcuate nucleus of a mouse brain
April 21, 2021

Scientists have identified a protein called the melanocortin 3 receptor as a potential drug target for treating obesity and eating disorders such as anorexia nervosa.

Artistic representation of a neural network
March 29, 2021

A new study from the University of Michigan offers insights into how neural circuitry in the brain operates and responds to feeding and hunger in real-time.

Mary Sue Coleman attends and LSI celebration in 2008
March 25, 2021

The building that houses the LSI will be named Mary Sue Coleman Hall. This naming recognizes her enduring commitment to the sciences and her role in spearheading the Life Sciences Institute, as well as her highly successful tenure as president of U-M.

Bing Ye discusses labwork with postdoctoral researcher Elizabeth Cebul
March 19, 2021

As we marked our first “Panniversary,” LSI professor and research associate dean Bing Ye reflected on how the institute has navigated a year of reduced research efforts, and the potential long-term impacts — both good and bad — on the scientific enterprise.

Cells fluorescing green in the presence of opioids
March 17, 2021

Researchers in the lab of Wenjing Wang, Ph.D., have designed a new chemical tool that can detect the presence of opioids at a cellular level.

Antibody blocks dengue virus's NS1 protein from interacting with host cells
January 7, 2021

A team of researchers has discovered an antibody that blocks the dengue virus’s ability to cause disease in mice. The findings open the potential for developing effective treatments and designing a vaccine for dengue and similar diseases.