Targeting an aspect of Down syndrome
U-M researchers have determined how a gene that is known to be defective in Down syndrome is regulated and how its dysregulation may lead to neurological defects, providing insights into potential therapeutic approaches to an aspect of the syndrome.
Neuronal regeneration and the two-part design of nerve cells
LSI reseachers have evidence that a single gene controls both halves of nerve cells, and their research demonstrates the need to consider that design in the development of new treatments for regeneration of nerve cells.
Trapping PCSK9 to lower cholesterol
Targeting the transport mechanism for a destructive protein lowers blood cholesterol levels in mice.