Cheung publications

Present-2011

Gregory BL, Cheung VG. Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth. Genome Res. 2014 Jan;24(1):52-63. PubMed Link

Wang IX, So E, Devlin JL, Zhao Y, Wu M, Cheung VG. ADAR regulates RNA editing, transcript stability, and gene expression. Cell Rep. 2013 Nov 14;5(3):849-60.  PubMed Link

Nayak RR, Bernal WE, Lee JW, Kearns MJ, Cheung VG. Stress-induced changes in gene interactions in human cells. Nucleic Acids Res. 2014 Feb 1;42(3):1757-71. PubMed Link

Wilson Sayres MA, Brookes AJ, Chanock SJ, Cheung VG, Goldstein DB, Jin L, Kwok PY. HGV2011: personalized genomic medicine meets the incidentalome. Hum Mutat. 2012 Mar;33(3):582-5. PubMed Link

Smirnov DA., Brady L., Halasa K., Morley M., Solomon S., Cheung VG. Genetic Variation in Radiation-Induced Cell Death. Genome Research 22: 332-339, 2012. PubMed Link

Li M, Wang IX, Li Y, Bruzel A, Richards AL, Toung JM & Cheung VG. Widespread RNA and DNA Sequence Differences in the Human Transcriptome. Science 333: 53-58, 2011. PubMed Link

Toung JM, Morley M, Li M & Cheung VG. RNA-Sequence Analysis of Human B-Cells. Genome Res 21(6):991-8, 2011. PubMed Link

 

2010-2005

Cheung VG, Nayak RR, Wang IX, Elwyn S, Cousins SM, Morley M, Spielman RS. Polymorphic cis- and trans-regulation of human gene expression. PLoS Biol 14;8(9) 2010. PubMed Link

Dombroski BA, Nayak RR, Ewens KG, Ankener W, Cheung VG & Spielman RS. Gene expression and genetic variation in response to endoplasmic reticulum stress in human cells. Amer J Hum Genet 86: 719-729, 2010. PubMed Link

Cheung VG., Sherman SL., Feingold E.: Genetic Control of Hotspots. Science 327(5967):791-2, 2010. PubMed Link

Nayak RR., Kearns M., Spielman RS. & Cheung VG.: Coexpression network based on natural variation in human gene expression reveals gene interactions and functions. Genome Res 19(11):1953-62, 2009. PubMed Link

Chowdhury R., Bois PR., Feingold E., Sherman SL. & Cheung VG.: Genetic analysis of variation in human meiotic recombination. PLoS Genet 5(9):e1000648, Epub 2009. PubMed Link

Cheung VG. & Spielman RS.: Genetics of human gene expression: mapping DNA variants that influence gene expression. Nat Rev Genet 10(9):595-604, 2009. PubMed Link

Smirnov DA., Morley M., Shin E., Spielman RS. & Cheung VG.: Genetic analysis of radiation-induced changes in human gene expression. Nature 459(7246):587-91, 2009. PubMed Link

Price AL., Patterson N., Hancks DC., Myers S., Reich D., Cheung VG., Spielman RS.: Effects of cis and trans genetic ancestry on gene expression in African Americans. PLoS Genet 4: e1000294, Epub 2008. PubMed Link

Smirnov DA., Cheung VG.: ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs. Am J Hum Genet 83: 243-53, 2008. PubMed Link

Cheung VG., Bruzel A., Morley M., Devlin JL., Spielman RS.: Monozygotic twins reveal germline contribution to allelic expression differences. Am J Hum Genet 82: 1357-60, 2008. PubMed Link

Wang X., Tomoso DJ., Chorley BN., Cho HY., Cheung VG., Kleeberger SR. & Bell DA.: Identification of polymorphic antioxident response elements in the human genome. Human Molecular Genetics 16: 1188-1200, 2007. PubMed Link

Spielman RS., Bastone LA., Burdick JT., Morley M., Ewens WJ. & Cheung VG.: Common genetic variants account for differences in gene expression among ethnic groups. Nature Genetics 39: 226-231, 2007. PubMed Link

Cheung VG., Burdick JT., Hirschmann D. & Morley M.: Polymorphic variation in human meiotic recombination. Amer. J. Hum. Genet 80: 526-530, 2007. PubMed Link 

Bruzel A., Cheung VG.: DNA Reassociation using oscillating phenol emulsions. Genomics 87(2): 286-289, 2006. PubMed Link

Burdick JT., Chen WM., Abecasis GR., Cheung VG.: In silico method for inferring genotypes in pedigrees. Nature Genetics 38(9): 1002-1004, 2006. PubMed Link

Cheung VG., Ewens WJ.: Heterozygous carriers of Nijmegen Breakage Syndrome have a distinct gene expression phenotype. Genome Research, 16(8): 973-979, 2006. PubMed Link

Jen KY., Cheung VG.: Identification of p53 target genes involved in ionizing radiation stress response. Cancer Research 65:7666-7673, 2005. PubMed Link

Cheung VG., Spielman RS., Ewens KG., Weber TM., Morley M. & Burdick JT.: Mapping determinants of human gene expression by regional and whole genome association. Nature 437: 1365-1369, 2005. PubMed Link

2004-2000

Smirnov D., Bruzel A., Morley M., Cheung VG.: Direct IBD Mapping: An Identical-by-Descent Mapping Method Without Genotyping. Genomics 83: 335-345, 2004. PubMed Link

Smirnov D., Burdick JT., Morley M., Cheung VG.: Method for manufacturing whole genome microarrays by rolling circle amplification. Genes, Chromosomes & Cancer, 40: 72-77, 2004. PubMed Link

Morley M., Molony CM., Weber T., Devlin JL., Ewens KG., Spielman RS., Cheung VG.: Genetic analysis of genome-wide variation in human gene expression. Nature 430: 743-747, 2004. PubMed Link

Correa CR., Cheung VG.: Genetic variation in radiation induced expression phenotypes. Amer J Hum Genet 75: 885-890, 2004. PubMed Link

Cheung VG., Conlin LK., Weber TM., Arcaro M., Jen KY., Morley M., Spielman RS.: Natural variation in human gene expression assessed in lymphoblastoid cells. Nature Genetics 33: 422-425, 2003. PubMed Link

Jen KY., Cheung VG.: Transcriptional response of lymphoblastoid cells to ionizing radiation. Genome Research 13:2092-2100, 2003. PubMed Link

Cheung VG., Jen KY., Weber TM., Morley M., Devlin JL., Ewens KG., Spielman RS.: Genetics of quantitative variation in human gene expression. Cold Spring Harbor Symposia on Quantitative Biology Vol 68 th: 403-407, 2003. Link to article

Watts JA., Morley M., Burdick JT., Fiori JL., Ewens WJ., Spielman RS., Cheung VG.: Gene expression phenotype in heterozygous carriers of ataxia telangiectasia. Amer J Hum Genet 71: 791-800, 2002. Link to article

Cheung VG. , & Spielman RS.: The genetics of variation in gene expression. Nature Genetics 32: 522-525, 2002. PubMed Link

Morley M., Arcaro M., Burdick J., Yonescu R., Reid T., Kirsch IR., Cheung VG.: GenMapDB: a database of mapped human BAC clones. Nucleic Acids Research 29(1): 144-147, 2001. PubMed Link

The International Human Genome Mapping Consortium.: A physical map of the human genome. Nature 409: 934-941, 2001. Link to article

Cheung VG., Nowak N., Jan W., et al.: Integration of cytogenetic landmarks into the draft sequence of the human genome. Nature: 953-958, 2001. PubMed Link

 

 1999-1998

Cheung VG., Morley M., Aguilar F., Massimi A., Kucherlapati R., Childs G.: Making and reading microarrays. Nature Genetics 21: 15-19, 1999.

Grant GR., Manduchi E., Cheung VG., Ewens WJ.: Significance testing for direct identity-by-descent mapping. Annals of Human Genetics 63(Pt 5): 441-454, 1999.

Cheung VG., Dalrymple HL., Narasimhan S., Watts J., Schuler G., Raap AK., Morley M., Bruzel A.: A resource of mapped human bacterial artificial chromosome clones. Genome Research 9(10): 989-993, 1999.

Cheung VG., Nelson SF.: Genomic mismatch scanning identifies human genomic DNA shared identical by descent. Genomics 47(1): 1-6, 1998.

Cheung VG., Gregg JP., Gogolin-Ewens KJ., Bandong J., Stanley CA., Baker L., Higgins MJ., Nowak NJ., Shows TB., Ewens WJ., Nelson SF., Spielman RS.: Linkage-disequilibrium mapping without genotyping. Nature Genetics 18(3): 225-230, 1998.