Weiss publications

Recent Articles

Tang, Y., Feinberg, T., Keller, E.T., Li, X-Y., and S.J. Weiss. Snail1/Slug-YAP/TAZ Complexes Control Skeletal Stem Cell Self-Renewal and Differentiation. Nature Cell Biology, 18:917-29, 2016, PMC5007193. PubMed Link

Ni, T., Li, X-Y, An, T., Fu, R., Rowe, R.G., Lin, Y., Scherer, A., Feinberg, T., Zheng, X., Lu, N., Guo, Q-L, Liu, X.S., Wu, Z-Q and S.J. Weiss. Snail1-Dependent p53 Repression Regulates Expansion and Activity of Tumor-Initiating Cells in Breast Cancer.  Nature Cell Biology, 2016, DOI: 10.1038/ncb3425.  PMID: 27749822. PubMed Link

Feinberg, T.Y., Rowe, R.G., Saunders, T.L and S.J.Weiss. Functional Roles of MT1-MMP and MT2-MMP in Early Postnatal Mammary Gland Development.  Development, 2016, 143:3956-3968. PMID: 27633994. PubMed Link

Jiang, L., Liu, Y., Shen, H., Weiss, S.J., Zhou, Y., and L. Rui. Adipose Snail1 Regulates Lipolysis and Lipid Partitioning by Epigenetically Suppressing Adipose Triacylglycerol Lipase (ATGL) Expression.  Cell Reports, In Press, 2016. PubMed Link

Fu, J., Li, S., Feng, R., Ma, H., Sabeh, F., Roodman, G. D., Wang, J., Robinson, S., Guo, X. E., Normolle, D., Mapara, M.Y., Weiss, S.J. and S. Lentzsch. Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease.  J. Clin Invest, 126:1759-72, 2016, PMC4855918. PubMed Link

Grande, M.T., Sanchez-Laorden, B., Lopez-Blau, C., De Frutos, D.A., Boutet, A., Arevalo, M., Rowe, R.G., Weiss, S.J., Lopez-Novoa, J. and M.A. Nieto.  Snail1-induced partial EMT drives renal fibrosis and supports targeted therapies.  Nature Medicine, 2015, 21:989-97, PMID: 26236989. PubMed Link

Turner, P.A., Tang, Y., Weiss, S.J. and A.V. Janorkar, 3-D spheroid cell model of in vitro adipocyte inflammation. Tissue Engineering, Part A, 2015, 21:1837-47, PMID: 25781458. PubMed Link

Dudley, D.T., Li, X.Y., Hu, C.Y., Kleer, C., Willis, A.L. and S.J. Weiss.  A 3-D matrix platform for the rapid generation of therapeutic anti-human carcinoma monoclonal antibodies. Proceedings of the National Academy of Sciences, USA, 2014, 111:14882-7, PMC4205646 PubMed Link

Kim, N. H., Y. H. Cha, H. S. Kim, S. E. Lee, J. K. Huh, J. K. Kim, J. M. Kim, J. K. Ryu, H. J. Kim, Y. Lee, S. Y. Lee, I. Noh, X. Y. Li, Weiss, S. J., Jahng, T. A.  and J. I. Yook. A platform technique for growth factor delivery with novel mode of action.  Biomaterials,2014 35:9888-96, PMID: 25218859. PubMed Link

Deng, L., Shang, L., Bai, S., Chen, J., He, X., Trevino, R.M., Chen, S., Li, X., Meng, X., Yu, B., Wang, X., Liu, Y., McDermott, S.P., Ariazi, A.E., Ginestier, C., Ibarra, I., Ke, J., Luther, T.K., Clouthier, S.G., Xu, L., Shan, G., Song, E., Yao, H., Hannon, G.J., Weiss, S.J., Wicha, M.S. and S. Liu.  microRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development. Cancer Research, 2014, 74:6648-60, PMID 25217527. PubMed Link

Wu, Z.-Q., Rowe, R.G., Lim, K.-C., Lin, Y., Willis, A.L., Tang, Y., Li, X.-Y., Nor, J.E., Maillard, I. and S.J. Weiss. A Snail1/Notch1 Signaling Axis Controls Embryonic Vascular Development.  Nature Communications, 2014, In Press. PubMed Link

Lin, Y., Li, X-Y., Willis, A.L., Liu, C., Chen, G. and S.J. Weiss.  Snail-dependent control of embryonic stem cell pluripotency and lineage commitment.  Nature Communications, 2014, 5:3070.  PubMed link

Tang, Y., Rowe, R.G., Botvinick, E.L., Kurup, A., Putnam, A.J., Seiki, M., Weaver, V.M.,Keller, E.T., Goldstein, S.A., Begun, D., Dai, J., Saunders, T.L. and S.J. Weiss.  Control of Mesenchymal Stem Cell Commitment by an MT1-MMP/YAP/TAZ Mechanotransduction Axis. Developmental Cell, 2013, 25:402–416. PubMed link  

Morell, M., Nguyen Duc, T., Willis, A., Syed, S., Lee, J., Deu, E., Deng, Y., Xiao, J., Turk, B., Jessen, J., Weiss, S.J. and M. Bogyo.  Coupling protein engineering with probe design to inhibit and image matrix metallo proteases with controlled specificity. Journal of the American Chemical Society, 2013, 135:9139-48. PubMed link

Wolf, K., te Lindert, M., Krause, M., Alexander, S., te Riet, J., Willis, A.L., Hoffman, R.M., Figdor, C.G., Weiss, S.J., and P. Friedl. Physical limits of cell migration: control by ECM space and nuclear deformation and tuning by proteolysis and traction force.  Journal of Cell Biology,  2013, 201:1069-84. PubMed link

S.J. Weiss. (2012). Viewpoint on cell migration in 3D systems. Nature Reviews Molecular Cell Biology, September 2012. Article link

Wu, Z.-Q., Brabletz, T., Fearon, E., Hu, C.Y., Li, X.-Y. and S.J. Weiss. The canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity. Proc Natl Acad Sci USA, 2012, 109:11312-7. PubMed link

Wu, Z-Q., Li, X-Y., Hu, C.Y., Ford, M., Kleer, C.G. and S.J. Weiss. Canonical Wnt signaling regulates Slug activity and links epithelial-mesenchymal transition with epigenetic BRCA1 Repression. Proc Natl Acad Sci USA , 2012, 109:16654-9. PubMed link

Shimizu-Hirota, R., Xiong, W., Baxter, B.T., Kunkel, S.L., Maillard, I., Chen, X.-Y., Sabeh, F., Liu, R., Li, X.-Y., and S.J. Weiss.  MT1-MMP-dependent regulation of a PI3Kd-nucleosome remodeling axis controls macrophage immune function. Genes & Development, 2012, 26:395-413. PubMed link

Weiss, S.J. Tying the collagen-sulfilimine knot. Nature Chemical Biology Vol. 9, September 2012. PubMed link

Kim, N.H., Kim, H.S., Li, X.-Y., Lee, I., Choi, H.-S., Kang, S.E., Cha, SY, Ryu, J.K., Yoon, D., Fearon, E.R., Rowe, R.G., Lee, S., Maher, C.A., Weiss, S.J.*, and J.I. Yook*.  A p53/miRNA-34 axis regulates snail1-dependent cancer cell epithelial-mesenchymal transition. Journal of Cell Biology, 2011, 195:417-33. (*co-senior authors). PubMed link

Li, X.-Y., Zhou, X., Rowe, G.R., Hu, Y., Schlaepfer, D.D., Ilic, D., Dressler, G., Park, A., Guan, J.-L. and S.J. Weiss.  Snail1 controls epithelial-mesenchymal lineage commitment in focal adhesion kinase-null embryonic cells. Journal of Cell Biology, 2011, 195:729-38. PubMed link

Kim, N.H., Kim, H.S., Kim, N.-G., Lee, I., Choi, H.S., Li, X.-Y., Kang, S.E., Cha, S.Y., Ryu, J.K., Na, J.M., Park, C., Kim, K., Lee, S., Gumbiner, B.M., Yook, J.I. and S.J. Weiss. (2011). P53 and microRNA-34 are suppressors of canonical Wnt signaling. Science Signaling, 2011, 4:ra71. PubMed link