News Archive

Schofield receives NSF Graduate Research Fellowship

April 13, 2012 - Schofield receives NSF Graduate Research Fellowship Michael Marie Schofield, a second-year PhD student whose research focuses on marine microbial natural products, received a Graduate Research Fellowship Program from the National Science Foundat... Learn more...

Piggott receives Weintraub Graduate Student Award

February 28, 2012 -  Piggott receives Weintraub Graduate Student Award Beverly Piggott, Life Sciences Institute (LSI) graduate student, has received the Weintraub Graduate Student Award. Working in the lab of LSI faculty member Shawn Xu, Piggott’s research f... Learn more...

Lim receives Sloan Research Fellowship

February 16, 2012 - Lim receives Sloan Research Fellowship Mi Hee Lim, Life Sciences Institute faculty member and an assistant professor in U-M’s chemistry department, was a recipient of the prestigious Sloan Research Fellowship for 2012. Her lab is examining how... Learn more...

U-M human embryonic stem cell line placed on national registry

February 14, 2012 - The University of Michigan’s first human embryonic stem cell line will be placed on the U.S. National Institutes of Health’s registry, making the cells available for federally funded research. It is the first of the stem cell lines derive... Learn more...

Lois Weisman named AAAS Fellow

January 13, 2012 - Lois Weisman named AAAS Fellow Life Sciences Institute faculty member Lois Weisman has been elected as one of the 2012 American Association for the Advancement of Science Fellows. Election as a Fellow, a tradition that began in 1874, is an honor ... Learn more...

So You Think You Can Do Research? Steve Weiss leads annual course on research for MDs-in-training

December 12, 2011 - So You Think You Can Do Research?  LSI faculty member Steve Weiss leads annual course on research for MDs-in-training. It was a beautiful summer day in Ann Arbor -- 80 degrees, high puffy clouds and a warm breeze wafting up from Palmer Field a... Learn more...

Life Sciences Institute names Jason Gestwicki as new Director of the Center for Chemical Genomics

October 11, 2011 - Life Sciences Institute names Jason Gestwicki as new Director of the Center for Chemical Genomics October 11, 2011—U-M Life Sciences Institute (LSI) has named Jason Gestwicki as the new Director of its Center for Chemical Genomics (CCG), a cam... Learn more...

U-M President Coleman lectures to LSI’s Business of Biology course

October 4, 2011 - Coleman speaks to Business of Biology class By Kaitlin Williams, Daily Staff Reporter University President Mary Sue Coleman addresses The Business of Biology class on Monday, Oct. 3 in the Michigan League. Students in The Business of Biology p... Learn more...

David Ginsburg discusses genomics in a Cell point/counterpoint editorial

October 3, 2011 - LSI professor and U-M clinician David Ginsburg argues the finer points of whether genomics has been successful from a clinical perspective in the latest issue of the journal Cell. Read the article   Visit the Ginsburg lab   ... Learn more...

Sherman lab receives award to start work on sustainable energy project

September 29, 2011 - LSI professor David Sherman and his lab are working on a project exploring the production of E. coli bacteria strains that can convert renewable biomass sources into next generation biofuels that have properties closer to gasoline and diesel than tod... Learn more...

Mi Hee Lim receives the Paul Saltman Award for outstanding research in biological inorganic chemistry

September 27, 2011 - Mi Hee Lim receives the Paul Saltman Award for outstanding research in the field of biological inorganic chemistry LSI professor Mi Hee Lim has been named the Paul Saltman lecturer at the 2012 Metals in Biology Gordon Research Conference, which will... Learn more...

Yukiko Yamashita receives MacArthur Foundation Fellowship

September 19, 2011 - LSI scientist Yukiko Yamashita receives MacArthur Foundation award Sept. 20, 2011--Life Sciences Institute stem cell biologist Yukiko Yamashita is one of three University of Michigan and 22 overall new MacArthur Fellows announced today by the John D... Learn more...

Shawn Xu receives the U-M Medical School Basic Science Research Award

September 13, 2011 - Shawn Xu receives the U-M Medical School Basic Science Research Award Shawn Xu, Life Sciences Institute (LSI) Associate Professor and Associate Professor, Department of Molecular and Integrative Physiology, has been selected to receive the 2011 Basi... Learn more...

Video about the U-M Biological Sciences Scholars Program features the LSI's Jason Gestwicki

August 31, 2011 - Video about the U-M Biological Sciences Scholars Program features the LSI's Jason Gestwicki Watch the video Started in 1998, the Biological Sciences Scholars Program was created as a vehicle for recruiting the most promising junior scientists in th... Learn more...

Stem cell scientist Jack Mosher recently appeared on Due Process to discuss the field

June 15, 2011 - LSI stem cell scientist Jack Mosher recently appeared along with LSI Leadership Council member Joe Schwarz and others on the show Due Process to discuss the scientific and legal issues surrounding the field in Michigan and beyond.   ... Learn more...

Georgios Skiniotis named to esteemed Pew Scholars Program

June 14, 2011 - Skiniotis named to the esteemed Pew Scholars Program   June 14, 2011. Georgios Skiniotis, Life Sciences Institute (LSI) research assistant professor and assistant professor of Biological Chemistry at the Medical School has been named a 2011 Pe... Learn more...

LSI co-sponsors a review series on obesity in the Journal of Clinical Investigation

June 1, 2011 - LSI co-sponsors a review series on obesity in the Journal of Clinical Investigation Check out the series... Learn more...

PHOTOS: Mi Hee Lim's lab receives gift and visit from local donor

June 1, 2011 - The Ties That Bind: Local Organization Makes a Difference at the LSI Ami Simms founded the Alzheimer's Art Quilt Initiative (AAQI) in 2006 to use her talents as a quilt maker (along with quilters across the country) in order to raise awareness abo... Learn more...

David Sherman's lab work is highlighted on the U-M Gateway

May 25, 2011 - Check out this highlight of David Sherman's lab work currently on the U-M gateway.... Learn more...

David Ginsburg receives Taubman scholar award

April 13, 2011 - David Ginsburg receives Taubman Scholar award April, 2011—Life Sciences Institute Research Professor David Ginsburg has received a Taubman Scholar award by the A. Alfred Taubman Institute here at U-M.   Ginsburg is among seven clinician... Learn more...

10th Annual LSI Symposium, May 5, 2011, Save the Date!

April 12, 2011 -   The 10th Annual Life Sciences Institute Symposium: Autophagy in Health and Disease, will take place from 8:45 am – 4:15 pm, Thursday, May 5, 2011 in the Biomedical Science Research Building, Auditorium.   This all-day event bring... Learn more...

Mike Finney, LSI Leadership Council member and President of the Michigan Economic Development Corp. discusses the state's future

March 22, 2011 - Mike Finney, Life Sciences Institute Leadership Council member and President of the Michigan Economic Development Council met with the three University Research Corridor Presidents on March 21, 2011 to discuss research-based economic development proj... Learn more...

Tesmer lab recently published a review on G protein-coupled receptors in the Journal of Biological Chemistry

March 16, 2011 - John Tesmer recently published a minireview on G protein-coupled receptors in the Journal of Biological Chemistry G protein-coupled receptors (GPCRs) represent the largest family of receptors in the human genome, and govern physiological responses t... Learn more...

Mi Hee Lim lab's latest work in neurodegenerative disease is highlighted on the cover of the journal Metallomics

March 16, 2011 - Metals in Neurodegenerative Disease Featured on the latest cover of the journal, Metallomics, Mi Hee Lim and her lab present a new class of small bifunctional molecules to target metal-associated amyloid-beta species and modulate metal-induced ... Learn more...

VIDEO: The LSI is the latest Out of the Blue video feature

March 15, 2011 - The Life Sciences Institute is the latest focus of the U-M show, Out of the Blue, which highlights departments and units across the U-M campus.   The eight-minute video describes our incredible science, our unique and effective “col... Learn more...

Dan Klionsky discusses autophagy in an article in Science News

March 15, 2011 - LSI scientist and the leading expert on the topic, Dan Klionsky discusses autophagy in an article in Science News. Read the full article  ... Learn more...

Noah Rosenberg receives the U-M Medical School Basic Science Research Award

December 10, 2010 - Noah Rosenberg receives the U-M Medical School Basic Science Research Award LSI Research Associate Professor Noah Rosenberg recently received the Basic Science Research Award at the U-M Medical School’s annual Dean’s Award Dinner.... Learn more...

Dan Klionsky designs cover of the journal Science

December 3, 2010 - Dan Klionsky designs cover of the journal Science The December 3, 2010 issue of the international journal Science features a cover showing autophagy designed by LSI professor Dan Klionsky in collaboration with one of his students, Zhou Du, and Dr. D... Learn more...

Jason Gestwicki discusses neurodegenerative disease in Medicine at Michigan story

November 23, 2010 -  Jason Gestwicki discusses neurodegenerative disease in Medicine at Michigan story   Read the eye-opening story about when good proteins go bad in the latest issue of Medicine at Michigan. ... Learn more...

The Center for Chemical Genomics collaborates to combat bioterror threats

November 3, 2010 - The Center for Chemical Genomics Collaborates with College of Pharmacy, Medical School to Find Therapies to Combat Bioterror Threats A group of scientists at the University of Michigan are in the midst of developing new therapeutics for Western Eq... Learn more...

A New York Times magazine article about cancer stem cells mentions the work in Sean Morrison’s lab on melanoma

November 1, 2010 - A New York Times article on October 29, 2010 about cancer stem cells mentioned the work in the area of melanoma of U-M Center for Stem Cell Biology Director Sean Morrison’s lab. Morrison was also quoted in the article.   Read the full ar... Learn more...

David Ginsburg wins award for Distinguished Research in Biomedical Sciences

October 29, 2010 - David Ginsburg wins award for Distinguished Research in Biomedical Sciences The Association of American Medical Colleges has recognized LSI research professor David Ginsburg, MD, with the Distinguished Research in the Biomedical Sciences Award. Rea... Learn more...

Alan Saltiel’s lab work and spinoff company featured on Xconomy website

October 4, 2010 - LSI Director Alan Saltiel’s lab work on Type 2 diabetes and the spinoff company based on his science, Vega Therapeutics, is featured in a story by Xconomy. Read the full Xconomy story.  Read more about Dr. Saltiel’s project Visit ... Learn more...

LSI's Innovation Partnership accelerates progress of four drug discovery projects in first year: read the full report

September 22, 2010 - LSI's Innovation Partnership accelerates progress of four drug discovery projects in first year  The Innovation Partnership at the Life Sciences Institute marked its first year with one project spinning off into a new company focusing on obesit... Learn more...

Recent Xu paper named one of the Top 7 in neuroscience by The Scientist

August 31, 2010 - The Scientist named Shawn Xu's recently published paper on mechanotransduction channels in Neuron as one of the top 7 neuroscience papers in the past 30 days. Read the full article in The Scientist. Read about Xu's paper.... Learn more...

Mi Hee Lim receives the 2010 Alzheimer’s Association New Investigator Research Grant

August 11, 2010 - Mi Hee Lim receives the 2010 Alzheimer’s Association New Investigator Research Grant     Research Assistant Professor Mi Hee Lim has been chosen to receive the 2010 Alzheimer’s Association New Investigator Research Grant. ... Learn more...

ABC News: Reprogrammed adult cells not an alternative to embryonic stem cells

July 27, 2010 - Two studies recently published in Nature and Nature Biotechnology show that reprogrammed adult stem cells “remember” what kind of cell they originally were. This further calls into question reprogrammed adult cells’ viability as an ... Learn more...

Sean Morrison featured in The Journal of Cell Biology

June 28, 2010 - In the current issue of The Journal of Cell Biology, LSI research professor Sean Morrison discusses his path to academia, science, and educating the public about stem cell research. Read the full interview. ... Learn more...

Bing Ye named to the prestigious Pew Scholars Program

June 17, 2010 - Bing Ye named to the prestigious Pew Scholars Program Bing Ye, Life Sciences Institute (LSI) research assistant professor and assistant professor of cell and developmental biology at the Medical School has been named a Pew Scholar. The Pew Charitab... Learn more...

LSI assistant research professor Shawn Xu wins the CBIS Young Investigator Award

February 4, 2010 - LSI assistant research professor Shawn Xu wins the CBIS Young Investigator Award   Dr. Shawn Xu, assistant research professor at the Life Sciences Institute and assistant professor of molecular and integrative physiology at the University of M... Learn more...

Sean Morrison to deliver the science keynote at the World Stem Cell Summit

June 3, 2010 - Sean Morrison to deliver the science keynote at the World Stem Cell Summit Sean Morrison, Director of the Center for Stem Cell Biology at the LSI,  was named by the Genetics Policy Institute to deliver the science keynote at the World Stem Cell... Learn more...

Rudenko Lab and the Center for Chemical Genomics ongoing collaboration yields results in understanding, treating depression

May 18, 2010 - In a news release from the National Mental Health Institute (NIMH), Director Thomas Insel mentions ongoing efforts to find small molecule activators of DFosB as a potential new class of resilience-boosting treatments for depression. The work is be... Learn more...

David Walt shares his thoughts on how Michigan can become a life sciences powerhouse

May 14, 2010 - LSI Board and Leadership Council member (and Xconomist), David Walt, answers the question, “What are the five things that entrepreneurs and innovators in Michigan can do to reinvigorate their regional economy?” on the Xconomy website. ... Learn more...

David Ginsburg receives the Pasarow Foundation Annual Medical Research Award in Cardiovascular Disease

May 10, 2010 - David Ginsburg, LSI Research Professor and Professor of Molecular Medicine and Genetics, Internal Medicine, is the recipient of the Robert J. and Claire Pasarow Foundation 22nd Annual Medical Research Award in Cardiovascular Disease.   At Mich... Learn more...

Sean Morrison, director of the U-M Center for Stem Cell Biology, interviewed by 60 Minutes

April 19, 2010 - Apr. 19, 2010 U-M researcher stresses hazards of unregulated stem cell clinics outside the U.S. in '60 Minutes' interview ANN ARBOR, Mich. — Patients should be wary of claims made by the operators of stem cell clinics outside the United S... Learn more...

Research assistant professor Mi Hee Lim named The Gray Family Fund Young Investigator

April 1, 2010 - LSI research assistant professor Mi Hee Lim has been named The Gray Family Fund Young investigator. She will present the talk, "Development of Small Molecules as Chemical Tools and Potential Therapeutic Agents for Alzheimer's Disease" at t... Learn more...

Sean Morrison testifies at U.S. Senate subcommittee hearing on stem cells

September 14, 2010 - Sean Morrison testifies at U.S. Senate subcommittee hearing on stem cells Sean Morrison, director of the University of Michigan's Center for Stem Cell Biology at the Life Sciences Institute, testified at a U.S. Senate subcommittee hearing titled &qu... Learn more...

LSI Leadership Council member David Canter named executive director of the North Campus Research Complex

June 11, 2010 - LSI Leadership Council member David Canter named executive director of the North Campus Research Complex Serving on the LSI’s Leadership Council since 2005, physician and scientist David Canter will take on the role of executive director for... Learn more...

Research assistant professor Ivan Maillard receives a two-year grant from the Sidney Kimmel Foundation for Cancer Research

April 9, 2010 - Good Surprises Meet a Prepared Mind LSI research assistant professor Ivan Maillard has been selected to receive a two-year grant from the Sidney Kimmel Foundation for Cancer Research. Maillard is among only 15 from across the country who will receiv... Learn more...

LSI's chief of research business development Janene Centurione featured in The Chronicle of Philanthropy

April 6, 2010 - LSI's chief of research business development, Janene Centurione, is featured in the current issue of The Chronicle of Philanthropy in an article discussing the rapidly changing world of fund raising.   Read the full article here.... Learn more...

Research professor Dan Klionsky featured in The Journal of Cell Biology

April 6, 2010 -   In the current issue of The Journal of Cell Biology, LSI research professor Dan Klionsky discusses his work, his teaching, and how he came to be a scientist in the first place.   Read the full interview here.  ... Learn more...

Slideshow & Story: Local donor teams up with LSI faculty Mi Hee LIm to fight Alzheimer's

March 24, 2010 -  Local Donor Teams Up with LSI Scientist Against Alzheimer’s Alzheimer's Art Quilt Initiative Visits the LSI To view a slideshow, click on the photo. image 2 | image 3 | image 4 | image 5| image 6| image 7| image 8| image 9| image... Learn more...

Video: Professor and researcher Dan Klionsky develops new ways to help students learn

March 11, 2010 - Professor and Researcher Dan Klionsky develops new ways to help students learn   LSI Research Professor and Professor of Molecular, Cellular, and Developmental Biology, Dan Klionsky discusses his method of “active learning” with U-... Learn more...

Where nature and design meet: LSI sponsors talk on biomimicry

March 9, 2010 - Where nature and design meet: LSI sponsors talk on biomimicry   The Life Sciences Institute is pleased to be a sponsor of the lecture, “Nature’s Industry: The Role of Biomimicry in the New Green Economy,” by Dr. Dayna Baumeis... Learn more...

LSI research assistant professor Sylvie Garneau-Tsodikova presents talk on antibiotics at Keystone Symposia

February 15, 2010 - Life Sciences Institute research assistant professor and John G. Searle assistant professor of medicinal chemistry Sylvie Garneau-Tsodikova presents a talk, "New Approaches to Combinatorial Biosynthesis of Antibiotics," at the Keystone... Learn more...

LSI Director Alan R. Saltiel receives the Goodman and Gilman Award in Receptor Pharmacology

February 4, 2010 - LSI Director Alan R. Saltiel Receives the Goodman and Gilman Award in Receptor Pharmacology   Dr. Alan Saltiel, Director of the Life Sciences Institute and John Jacob Abel Professor of Internal Medicine and Molecular and Integrative Physiology... Learn more...

U-M to begin accepting donated embryos for stem cell research

December 9, 2009 -  By Jim Erickson News Service   ANN ARBOR, Mich.—University of Michigan researchers have received approval to begin accepting donated embryos that will be used to derive the university's first human embryonic stem cell lines. The cell ... Learn more...

LSI scientists collaborate with corporate partners on metabolic disease research

November 19, 2009 -  LSI scientists collaborate with corporate partners on metabolic disease research LSI scientists working on metabolic disease projects with corporate partners at Johnson & Johnson Pharmaceutical Research and Development are highli... Learn more...

LSI research associate professor John Tesmer wins the 2010 ASBMB Schering-Plough Research Institute Award

November 6, 2009 - LSI research associate professor John Tesmer wins the 2010 ASBMB Schering-Plough Research Institute Award Dr. John J. G. Tesmer, a research associate professor at the Life Sciences Institute and associate professor of pharmacology at the Medica... Learn more...

U-M scientists win $6.8 million in federal stimulus-fund grants for stem cell research

October 22, 2009 - U-M scientists win $6.8 million in federal stimulus-fund grants for stem cell research By Jim Erickson News Service ANN ARBOR, Mich. --- University of Michigan researchers have been awarded 13 federal stimulus-fund grants, totaling $6.8 million,... Learn more...

2010 World Stem Cell Summit to be held in Detroit, co-hosted by Michigan's University Research Corridor

October 15, 2009 - 2010 World Stem Cell Summit to be held in Detroit, co-hosted by Michigan's University Research Corridor By Jim Erickson News Service DETROIT --- Gov. Jennifer M. Granholm announced today that the 2010 World Stem Cell Summit will be held in Detro... Learn more...

LSI’s Innovation Partnership nominated for “Deals of the Year” award by AnnArbor.com Business Review

October 23, 2009 - LSI’s Innovation Partnership, a program that provides funds and business mentorship to faculty projects on their way to commercialization, is proud of the nomination by Ann Arbor.com Business Review for “Deal of the Year” in the Hea... Learn more...

Statement by Sean Morrison, Director of UM's Center for Stem Cell Biology, on bills to restrict stem cell research in Michigan

October 29, 2009 - Statement from Sean J. Morrison, director of the University of Michigan's Center for Stem Cell Biology, regarding the Senate Health Policy Committee hearing on bills to restrict stem cell research in Michigan:   ANN ARBOR, Mich.—Last Nov... Learn more...

New LSI lab provides super-sharp 3-D views of protein complexes

October 1, 2009 - New LSI lab provides super-sharp 3-D views of protein complexes By Jim Erickson News Service   At a new state-of-the art electron microscopy lab within the Life Sciences Institute, Georgios Skiniotis “quick-freezes” protein com... Learn more...

LSI Faculty Member Rowena Matthews describes her “Love Affair with Vitamins” in the Journal of Biological Chemistry

September 24, 2009 - LSI Faculty Member Rowena Matthews describes her “Love Affair with Vitamins” in the Journal of Biological Chemistry Research Professor Emeritus Rowena Matthews tells the story of her pioneering scientific career and her fascination with ... Learn more...

LSI Director Reports on Successes in University Regents Meeting

September 18, 2009 -  LSI Director Reports on Successes in University Regents Meeting LSI Director Alan Saltiel made a presentation to the University’s Regents at their public meeting on September 17, 2009. The presentation highlighted the successes of LSI in ... Learn more...

Research Fellow gets award from the Children’s Tumor Foundation

August 27, 2009 - Johanna Buchstaller, Life Sciences Institute Research Fellow, gets award from Children’s Tumor Foundation for work on neurofibromatosis. By Kevin Brown In her lab on the fifth floor of the Life Sciences Institute, Johanna Buchstaller studie... Learn more...

Perrigo Fellowship at LSI Trains – and Helps to Keep – Top Talent in Michigan

August 4, 2009 - Perrigo Fellowship at LSI Trains – and Helps to Keep – Top Talent in Michigan By: Jim Reisch, Office of University Development Michigan powered the engine of America’s twentieth-century manufacturing economy. Now the Perrigo Under... Learn more...

LSI Faculty member Sean Morrison comments on revised NIH guidelines on human embryonic stem cell research

July 6, 2009 - LSI Faculty member Sean Morrison comments on revised NIH guidelines on human embryonic stem cell research Statement from Sean J. Morrison, director of the University of Michigan's Center for Stem Cell Biology, in response to the National Institutes ... Learn more...

LSI Faculty Member John Kim named 2009 Pew Scholar

September 16, 2009 - LSI Faculty Member John Kim named 2009 Pew Scholar June 16, 2009 - John Kim, LSI faculty member and assistant professor in the U-M Medical School's Department of Human Genetics, was named as one of seventeen Pew Scholars in the Biomedical Sciences f... Learn more...

LSI Faculty member Yukiko Yamashita receives WICB Career Recognition Award from the American Society for Cell Biology

May 7, 2009 - LSI Faculty member Yukiko Yamashita receives WICB Career Recognition Award from the American Society for Cell Biology LSI Research Assistant Professor Yukiko Yamashita is the recipient of the 2009 Women in Cell Biology's (WICB) Career Recognition A... Learn more...

LSI faculty member Sean Morrison awarded $50,000 Grant from Liddy Shriver Sarcoma Initiative

April 5, 2009 - LSI faculty member Sean Morrison awarded $50,000 Grant from Liddy Shriver Sarcoma Initiative LSI faculty member and Director of the U-M Center for Stem Cell Biology, Dr. Sean Morrison, received a $50,000 grant from The Liddy Shriver Sarcoma Initiati... Learn more...

LSI’s Innovation Partnership targets deadly diseases through novel initiative

March 30, 2009 - LSI’s Innovation Partnership targets deadly diseases through novel initiative Cancer, diabetes, strep infections and neurodegenerative diseases such as Alzheimer’s are the first targets of a novel University of Michigan program to shephe... Learn more...

LSI announces April 2009 Symposium - Evolutionary Biology: 150 Years after the Origin

March 10, 2009 - LSI announces April 2009 Symposium - Evolutionary Biology: 150 Years after the Origin Top researchers specializing in evolutionary biology will discuss their latest findings at the Life Sciences Institute’s eighth annual symposium “Evolu... Learn more...

New embryonic stem cell lab launched with support from UM Center for Stem Cell Biology and the LSI

March 9, 2009 - New embryonic stem cell lab launched with support from UM Center for Stem Cell Biology and the LSI The University of Michigan today announced the formation of a consortium to create new embryonic stem cell lines that will aid the search for disease ... Learn more...

LSI's Innovation Partnership cited by Ann Arbor Business Review as potential solution to languishing pharmaceutical pipeline

February 11, 2009 - LSI's Innovation Partnership cited by Ann Arbor Business Review as potential solution to languishing pharmaceutical pipeline In this week's edition of the Ann Arbor Business Review, LSI Director Alan Saltiel was interviewed on his perspective on Mic... Learn more...

Two U-M cancer researchers share Damon Runyon Foundation award

January 22, 2009 - Two U-M cancer researchers share Damon Runyon Foundation award ANN ARBOR, Mich.--- Life Sciences Institute researcher Dr. Ivan Maillard and Dr. Yi Zhang of the U-M Medical School will share a $450,000 Innovation Award from the Damon Runyon Cancer R... Learn more...

LSI and MICHR Announce Funding Opportunity for Translastional Research in the Life Sciences

January 20, 2009 - LSI and MICHR Announce Funding Opportunity for Translastional Research in the Life Sciences Sponsored by U-M Life Sciences Institute (LSI) and the Michigan Institute for Clinical and Health Research (MICHR) MICHR and the LSI seek to support transla... Learn more...

2009 Perrigo Fellowship Applications Now Available

January 9, 2009 - 2009 Perrigo Fellowship Applications Now Available The Perrigo Undergraduate Research Fellowship at LSI is accepting applications for the Summer 2009 program. This summer research opportunity is open to all undergraduate students attending a colleg... Learn more...

LSI faculty member John Tesmer to receive 2009 John J. Abel Award

January 5, 2009 - LSI faculty member John Tesmer to receive 2009 John J. Abel Award John J. G. Tesmer, LSI faculty member and Professor of Pharmacology, will receive ASPET’s John J. Abel Award in Pharmacology for 2009. The Abel Award, named after the founder... Learn more...

U-M scientists plan stem cell research as new state law goes into effect

December 20, 2008 - U-M scientists plan stem cell research as new state law goes into effect A new state law loosening restrictions on embryonic stem cell research goes into effect today, and University of Michigan scientists are busy planning projects that could lead ... Learn more...

Four LSI faculty named AAAS Fellows; Seven U-M scientists receive honor

December 19, 2008 - Four LSI scientists named AAAS Fellows; Seven U-M scientists receive honor Seven University of Michigan faculty members, four of whom from the LSI, are among 486 newly elected Fellows of the American Association for the Advancement of Science. Elec... Learn more...

Michigan voters expand stem cell research with passage of Proposition 2

November 5, 2008 - Michigan voters expand stem cell research with passage of Proposition 2 Proposal 2, approved by voters in the Nov.4, 2008 general election, overturns a 1978 Michigan law that prohibited creation of new stem cell lines from discarded embryos. The ame... Learn more...

LSI Faculty member Patrick Hu featured in Ann Arbor News

October 20, 2008 - LSI Faculty member Patrick Hu featured in Ann Arbor News LSI Faculty member Patrick Hu and his work on C. elegans was profiled on October 21, 2008 in the Ann Arbor News. Dr. Hu, an Assistant Professor of Internal Medicine, uses the worms to learn ... Learn more...

State Stem Cell Policy Deserves National Attention

October 15, 2008 - State Stem Cell Policy Deserves National Attention LSI Faculty member and Director of the U-M Center for Stem Cell Biology Sean Morrison and LSI Managing Director Liz Barry discuss Michigan's restrictive stem cell laws in this week's online version... Learn more...

LSI Faculty member David Sherman recipient of the Arthur C. Cope Scholar Award

September 25, 2008 - LSI Faculty member David Sherman recipient of the Arthur C. Cope Scholar Award David Sherman was chosen as on of ten recipients of the Arthur C. Cope Scholar Award. The Arthur C. Cope Scholar Awards were established in 1984 by the ACS Board of Dire... Learn more...

LSI directorship named for President Mary Sue Coleman

September 15, 2008 - LSI directorship named for President Mary Sue Coleman ANN ARBOR, Mich.--- The directorship of the Life Sciences Institute will be named for President Mary Sue Coleman to recognize the key role she has played in the development of the interdisciplina... Learn more...

John Tesmer receives Basic Science Research Award

September 2, 2008 - John Tesmer receives Basic Science Research Award John Tesmer, Research Associate Professor in the LSI and Associate Professor in the Department of Pharmacology was honored with the U-M Medical School Basic Science Research Award. This award is to ... Learn more...

LSI Faculty member Gabby Rudenko receives NARSAD's Prestigious 2008 Young Investigator Award

August 27, 2008 - LSI Faculty member Gabby Rudenko receives NARSAD's Prestigious 2008 Young Investigator Award Gabby Rudenko, LSI Research Assistant Professor and Assistant Professor in the Department of Pharmacology is one of three University of Michigan scientists ... Learn more...

LSI announces funding opportunity for collaborative research with Israeli universities

July 29, 2008 - Request for Proposals: The U-M/Israeli Universities Partnership for Research The U-M/Israeli Universities Partnership for Research, administered by the Life Sciences Institute, seeks proposals for innovative and collaborative research projects in th... Learn more...

Bridging the "valley of death": LSI launches innovative research fund

June 9, 2008 - U-M Life Sciences Institute bridges "Valley of Death" with new fund The University of Michigan's Life Sciences Institute is launching a novel program to shepherd promising biomedical discoveries from the lab bench to the marketplace. Call... Learn more...

Yamashita named Searle Scholar

June 9, 2008 - Yukiko Yamashita named a Searle Scholar Yukiko Yamashita, Life Sciences Institute Reseach Assistant Professor, member of the University of Michigan Center for Stem Cell Biology, and Assistant Professor of Cell and Developmental Biology at the Univ... Learn more...

LSI announces May 2008 Symposium: Focus on Chemical Biology

April 21, 2008 - LSI announces May 2008 Symposium: Focus on Chemical Biology Symposium schedule Top researchers specializing in chemical biology will discuss their latest findings at the Life Sciences Institute’s seventh annual symposium: Focus on Chemical ... Learn more...

Patrick Hu granted a Kimmel Scholar Award for cancer research

April 11, 2008 - Patrick Hu granted a Kimmel Scholar Award for cancer research Dr. Patrick Hu, LSI Research Assistant Professor and Assistant Professor of Hematology/Oncology in the Department of Internal Medicine at the University of Michigan Medical School, was ... Learn more...

CCG and collaborators awarded grant to study rare diseases

March 28, 2008 - CCG and collaborators awarded grant to study rare diseases The Center for Chemical Genomics is awarded a one-time pilot grant in the amount of $75,000. The project, entitled "Small Molecule Mediated Protein Folding in Rare Disease Targets,&quo... Learn more...

Center for Stem Cell Biology sponsors documentary film screening March 12 at Michigan Theatre

February 29, 2008 - Center for Stem Cell Biology sponsors documentary film screening March 12 at Michigan Theatre February 29, 2008 - Life is for the Living, a documentary film with an introduction by University of Michigan alumnus and CBS 60 Minutes' Mike Wallac... Learn more...

Center for Stem Cell Biology sponsors documentary film screening March 12 at Michigan Theatre

February 29, 2008 - Center for Stem Cell Biology sponsors documentary film screening March 12 at Michigan Theatre February 29, 2008 - Life is for the Living, a documentary film with an introducti... Learn more...

Rosenberg lab's research into genetics reaches national press

February 24, 2008 - Rosenberg lab's research into genetics reaches national press Strides made by Noah Rosenberg and his colleagues have garnered attention from mainstream news outlets. Learn more about the study Read articles published in: Los Angeles Times Philad... Learn more...

Kondrashov discusses population genetics data in Nature

February 21, 2008 - Kondrashov discusses population genetics data in Nature LSI faculty member Alexey Kondrashov is featured in a Nature article on the interpretation of data in population-genetics studies, titled "On the origin of deleterious mutations." Fr... Learn more...

Gift launches fund to support stem cell research at University of Michigan

February 18, 2008 - Gift launches fund to support stem cell research at University of Michigan Gift from Robert and Marge Alpern will aid U-M scientists' efforts in all types of stem cell research The University of Michigan Medical School and the Center for Stem Cell ... Learn more...

"Let U-M compete in science," writes LSI Leadership Council member

February 12, 2008 - "Let U-M compete in science," writes LSI Leadership Council member Michael B. Staebler has written an op-ed piece for the Detroit News regarding Michigan legislative issues that impact stem cell research. From the article: While "li... Learn more...

Sean Morrison quoted in Wired article on California stem cell labs

January 17, 2008 - Sean Morrison quoted in Wired article on California stem cell labs LSI faculty and Center for Stem Cell Biology head Sean Morrison is quoted in a Wired article about state funding for researchers in California. Read the article on Wired.com... Learn more...

LSI's Sean Morrison receives the American Association of Anatomists 2008 Harland Winfield Mossman Award

December 31, 2007 - LSI's Sean Morrison receives the American Association of Anatomists 2008 Harland Winfield Mossman Award Sean Morrison, Director of the University of Michigan Center for Stem Cell Biology won the 2008 Harland Winfield Mossman Award in recognition of ... Learn more...

Kumar named "Top" rising PI by Genome Technology Magazine

December 13, 2007 - Kumar named "Top" rising PI by Genome Technology Magazine LSI Faculty Anuj Kumar's is featured in the December/January issue of Genome Technology. Read the article online at genome-technology.com (requires free login) Download the articl... Learn more...

U-M President Mary Sue Coleman praises LSI faculty in address

November 15, 2007 - U-M President Mary Sue Coleman praises LSI faculty in address LSI faculty Janet Smith and David Sherman are mentioned in today's address titled "Five Years Forward: An Address to the University of Michigan Community." Read or watch the sp... Learn more...

Sean Morrison interviewed on Detroit Today about stem cell research

November 5, 2007 - Sean Morrison interviewed on Detroit Today about stem cell research Sean Morrison was interviewed for a segment on stem cell research on the November 5, 2007, edition of Detroit Today on WDET 101.9 FM, Detroit Public Radio. An audio clip is forthco... Learn more...

Sean Morrison receives the McCullough and Till Award

October 31, 2007 - LSI's Sean Morrison receives the McCullough and Till Award Sean Morrison, Director of the Center for Stem Cell Biology and Research Associate Professor at the Life Sciences Institute of the University of Michigan won the McCullough and Till Award, a... Learn more...

Janet Smith named AAAS Fellow

October 25, 2007 - Janet Smith named AAAS Fellow Janet L. Smith, research professor at the Life Sciences Institute at the University of Michigan, has been awarded the distinction of AAAS Fellow. Election as a Fellow is an honor bestowed upon AAAS members by their peer... Learn more...

Fall 2007 exploreLSI newsletter released

October 18, 2007 - Fall 2007 exploreLSI newsletter released The newest issue of LSI's newsletter has been released. Volume 3, issue 2 of exploreLSI features stem cell research at the Center for Stem Cell Biology, with faculty interviews and current events in the life ... Learn more...

'U' scientists welcome stem cell ban repeal

October 17, 2007 - 'U' scientists welcome stem cell ban repeal The Center for Stem Cell Biology is featured in a discussion of stem cell legislation in today's Michigan Daily. From the article: A ballot proposal committee formed at the beginning of October is aiming ... Learn more...

LSI Director Alan Saltiel and diabetes research featured in New York Times

October 16, 2007 -  Click on any of the images from the article above to see a larger version. LSI Director Alan Saltiel and diabetes research featured in New York Times LSI Director Alan Saltiel is featured in a New York Times article on current findings in resear... Learn more...

Stem cell center has 4th faculty member

October 10, 2007 - Stem cell center has 4th faculty member With the arrival of researcher Ivan Maillard, the center for stem cell biology at the University of Michigan has four faculty members... Read the full article at MLive.com... Learn more...

Stem cell dispute U-M researchers bring long-held hypothesis on how cells protect themselves into debate

September 24, 2007 - Stem cell dispute U-M researchers bring long-held hypothesis on how cells protect themselves into debate An article in today's Ann Arbor News features the Center for Stem Cell Biology's research that "has dealt a blow to a long-held hypothesis ... Learn more...

Daniel Klionsky featured in Washington Post article on teaching

September 23, 2007 - Daniel Klionsky featured in Washington Post article on teaching LSI faculty member Daniel Klionsky is among the professors profiled in a piece on teaching science in higher education. Read the full article at washingtonpost.com.... Learn more...

Autophagy: from phenomenology to molecular understanding in less than a decade by Dan Klionsky in Nature Reviews Molecular Cell

September 21, 2007 - Autophagy: from phenomenology to molecular understanding in less than a decade "Autophagy: from phenomenology to molecular understanding in less than a decade" by Dan Klionsky is appearing in Nature Reviews Molecular Cell Biology. Downloa... Learn more...

Noah Rosenberg featured in New York Times and Science Magazine

June 26, 2007 - Noah Rosenberg featured in New York Times and Science Magazine LSI faculty Noah Rosenberg has been featured in both the June 22 Science cover story and a June 26 New York Times article, both on population genetics. Read the article on the New York ... Learn more...

LSI's Shawn Xu Named One of Twenty of America's Most Promising Scholars, Named To Highly Selective Pew Scholars Program

June 20, 2007 - LSI's Shawn Xu Named One of Twenty of America's Most Promising Scholars, Named To Highly Selective Pew Scholars Program Xian-Zhong Shawn Xu, Life Sciences Institute Research Assistant Professor and Assistant Professor of Molecular and Integrative Ph... Learn more...

Klionsky featured in article on cell research at Penn

June 14, 2007 - Klionsky featured in article on cell research at Penn Daniel Klionsky is quoted in a Philadephia Inquirer article about cell research taking place at the University of Pennsylvania. Read the article at Philly.com... Learn more...

U-M, Perrigo name 2007 undergraduate research fellows

June 12, 2007 - U-M, Perrigo name 2007 undergraduate research fellows ANN ARBOR, Mich.---The Life Sciences Institute (LSI) of the University of Michigan and the Perrigo Company, a pharmaceutical and nutritional products manufacturer based in Allegan, Michigan, have... Learn more...

Genome Technology features LSI

May 30, 2007 - Genome Technology features LSI Genome Technology Magazine features LSI's unique approach to collaborative science. Read the article (PDF)... Learn more...

Stem cell research could boost Michigan economy

May 18, 2007 - Stem cell research could boost Michigan economy May 18, 2007 - Liz Barry, LSI's managing director, provided an editorial advocating the use of embryonic stem cells in research in today's Detroit Free Press. Read the article on the Free Press we... Learn more...

Stem Cell Research and LSI Featured in WWJ Newsradio Podcast

May 4, 2007 - Stem Cell Research and LSI Featured in WWJ Newsradio Podcast May 2, 2007 - WWJ Newsradio 950 from Detroit interviewed U-M President Mary Sue Coleman and Center for Stem Cell Research head Sean Morrison in a story about life science jobs in Michiga... Learn more...

David Ginsburg elected to National Academy of Sciences

May 1, 2007 - David Ginsburg Elected Member of National Academy of Sciences May 1, 2007 --- The National Academy of Sciences today announced the election of Life Sciences Institute Research Professor, David Ginsburg, M.D. to its ranks. Election to the Academy ... Learn more...

LSI announces May symposium: Frontiers in Stem Cell Biology

April 11, 2007 - LSI announces May symposium: Frontiers in Stem Cell Biology ANN ARBOR -- Top researchers specializing in stem cell biology will discuss their latest findings at the Life Sciences Institute's sixth annual symposium: Frontiers in stem Cell Biology o... Learn more...

First 2007 Edition of the exploreLSI Newsletter Released

April 11, 2007 - First 2007 Edition of the exploreLSI Newsletter Released March 2007 - Interviews with faculty and columns by leaders in the U-M and national scientific community, round out information about the latest cutting-edge research at the LSI. Download... Learn more...

New Frontiers: The Changing Face of Life Sciences at the University of Michigan

March 16, 2007 - New Frontiers: The Changing Face of Life Sciences at the University of Michigan Wednesday, March 21, 2007, 11:30am - 1:00pm Billie S. Farnum Building, Room 810 Join the Wolverine Caucus for a discussion with LSI director Dr. Alan Saltiel about... Learn more...

The Seduction of Scale: Artists engaging nature in a micro/macro world

March 16, 2007 - The Seduction of Scale: Artists engaging nature in a micro/macro world 11 a.m.-5 p.m. weekdays from April 2 – 30, 2007. Event The growing connections between art and science are the focus of The Seduction of Scale, a group exhibition at th... Learn more...

Center for Stem Cell Biology Featured in Local and Statewide Discussion of Bio Research

March 7, 2007 - Center for Stem Cell Biology Featured in Local and Statewide Discussion of Bio Research Sean Morrison and the Center for Stem Cell Biology are featured in several recent Ann Arbor News articles: Stem cell research limits hurt Michigan Legislat... Learn more...

LSI's "House Air" System Receives Mention by Industry Journal

April 10, 2007 - LSI's "House Air" System Receives Mention by Industry Journal March 2007 - The journal of the American Society of Heating, Refrigerating and Air-Conditional Engineers (ASHRAE) mentions LSI in its March issue. ASHRAE member Ronald Henning implemen... Learn more...

U-M scientists hope to turn blue-green algae's cancer-fighting compound into a useful drug

February 20, 2007 - U-M scientists hope to turn blue-green algae's cancer-fighting compound into a useful drug February 19, 2007 LSI faculty member David Sherman and his lab have been featured in an Ann Arbor News story about their research into alternative cancer... Learn more...

ThermoFisher Scientific/CCG Pilot Project awards announced

January 11, 2007 - ThermoFisher Scientific/CCG Pilot Project awards announced January 10, 2007 ThermoFisher Scientific in conjunction with the University of Michigan Life Sciences Institute is pleased to announce the awards for its second annual Center for Chemi... Learn more...

2007 Perrigo Fellowship Applications now available

December 5, 2006 - Perrigo Undergraduate Fellowship Program The Perrigo Company and the University of Michigan Life Sciences Institute are offering summer fellowships to highly qualified undergraduate students currently enrolled at any university of college in Michi... Learn more...

U-M Center receives funds for embryonic stem cell research

November 14, 2006 - U-M Center receives funds for embryonic stem cell research October 23, 2006 The University of Michigan has raised over a quarter of a million dollars in private funds to support a project on human embryonic stem cell research currently not el... Learn more...

Fifth Edition of the exploreLSI Newsletter Released

December 4, 2006 - Fifth Edition of the exploreLSI Newsletter Released October 2006 - This month's newsletter focuses on the importance of basic scientific research to answer problems leading to new treatments for human diseases. Interviews with faculty and columns by... Learn more...

Graduate Student Awards in Chemistry and Chemical Biology

October 9, 2006 - Graduate Student Awards in Chemistry and Chemical Biology October 10, 2006, ANN ARBOR, Michigan – The first awards under a collaboration between Pfizer Inc. and the Departments of Chemistry, Medicinal Chemistry and the Center for Chemical Genomi... Learn more...

Kumar Featured in Science Magazine

December 4, 2006 - Kumar Featured in Science Magazine Sept. 29, 2006 - Anuj Kumar's development of Organelle DB, a searchable database of cellular locales. Read the story (PDF) ... Learn more...

Life Sciences Institute Announces Five New Faculty

September 24, 2006 - Life Sciences Institute Announces Five New Faculty September 25, 2006, ANN ARBOR, Mich.---The Life Sciences Institute (LSI) at the University of Michigan has hired five new faculty members, bringing the total faculty in the multidisciplinary resea... Learn more...

U-M, Perrigo Name 2006 Undergraduate Research Fellows

November 6, 2006 - U-M, Perrigo Name 2006 Undergraduate Research Fellows June 13, 2006 ANN ARBOR, Mich.---The Life Sciences Institute (LSI) of the University of Michigan and the Perrigo Company, a pharmaceutical and nutritional products manufacturer based in Allegan,... Learn more...

U-M Biologist Wins Howard Hughes Medical Institute Teaching Grant

May 31, 2006 - U-M Biologist Wins Howard Hughes Medical Institute Teaching Grant June 1, 2006, CHEVY CHASE, Maryland --- The University of Michigan has been awarded a $1.5 million grant by the Howard Hughes Medical Institute (HHMI) to further develop some innova... Learn more...

LSI announces May symposium: Molecular Insights into Metabolic Disease

November 8, 2006 - LSI announces May symposium: Molecular Insights into Metabolic Disease April 5, 2006 ANN ARBOR, Mich--- Top researchers specializing in the development of new therapies for diabetes, obesity, and muscular diseases will discuss their latest findings... Learn more...

Moving in the Sixth Sense

November 6, 2006 - Moving in the "Sixth Sense" March 29, 2006 ANN ARBOR, Mich---One of our first science lessons included learning the five senses: touch, sight, smell, hearing and taste. The "sixth sense," not the E.S.P. kind, but the kind that r... Learn more...

Dr. Sean Morrison Brings Promise and Enthusiasm to U-M Stem Cell Research

March 18, 2006 - Dr. Sean Morrison Brings Promise and Enthusiasm to U-M Stem Cell Research March 18, 2006, ANN ARBOR, Michigan – “A scientist is like a storyteller,” says Sean Morrison, director of the University of Michigan’s Center for Stem Cell Biolog... Learn more...

Klionsky Named National Academies Biology Mentor

November 6, 2006 - Klionsky Named National Academies Biology Mentor February 23, 2006 ANN ARBOR, Mich---LSI Research Professor Daniel J. Klionsky has been named an Education Mentor in the Life Sciences by The National Academies February 21, 2006 along with 20 other s... Learn more...

UM Life Sciences Institute and Fisher Biosciences Announce UM Grant Winners

November 6, 2006 - UM Life Sciences Institute and Fisher Biosciences Announce UM Grant Winners February 2, 2006 ANN ARBOR, Mich---The Center for Chemical Genomics Pilot Project Initiative, a collaboration between the University of Michigan Life Sciences Institute and... Learn more...

Modeling Cell's Messengers

November 6, 2006 - Modeling Cell's Messengers December 9, 2005 Humans have millions of cells to conduct the business of the body. By exchanging chemical signals, cells "talk" to each other to perform functions like regulating blood pressure, converting food... Learn more...

LSI Director Alan Saltiel elected to Institute of Medicine

November 6, 2006 - LSI Director Alan Saltiel elected to Institute of Medicine October 24, 2005 ANN ARBOR, Mich.---Life Sciences Institute Director Alan R. Saltiel was elected to The Institute of Medicine of the National Academy of Sciences October 24, 2005 along with... Learn more...

Fisher Biosciences and the University of Michigan Collaborate to Develop New Life-Sciences Technologies

November 7, 2006 - Fisher Biosciences and the University of Michigan Collaborate to Develop New Life-Sciences Technologies October 12, 2005 HAMPTON, New Hampshire---On behalf of its Biosciences group, Fisher Scientific International Inc. has launched a five-year coll... Learn more...

U-M Launches Center for Stem Cell Biology

November 6, 2006 - U-M Launches Center for Stem Cell Biology September 19, 2005 ANN ARBOR, Mich. -- President Mary Sue Coleman today announced a significant expansion of the University of Michigan 's efforts in stem cell science with the creation of a new interdiscip... Learn more...

The Origin of Fat Cells

November 6, 2006 - The Origin of Fat Cells September 13, 2005 ANN ARBOR, Mich.---A new study in the journal Cell Metabolism explains some crucial steps in how fat cells are formed. The findings may help in understanding chronic diseases, such as obesity and diabetes.... Learn more...

LSI/Weizmann Launch Partnership

November 7, 2006 - LSI/Weizmann Launch Partnership August 16, 2005 ANN ARBOR, Mich.---The Life Sciences Institute (LSI) at the University of Michigan and the Weizmann Institute of Science (WIS) in Israel launched a partnership for scientific collaboration and exchang... Learn more...

Alan Saltiel Reappointed as Director of the Life Sciences Institute

November 6, 2006 - Alan Saltiel Reappointed as Director of the Life Sciences Institute July 22, 2005 ANN ARBOR, Mich--- At their monthly meeting July 21, 2005, the Regents of the University of Michigan approved the reappointment of Alan R. Saltiel as director of the ... Learn more...

Two LSI Research Professors to be Inducted into the American Academy of Arts and Sciences

November 6, 2006 - Two LSI Research Professors to be Inducted into the American Academy of Arts and Sciences Monday, May 2, 2005 CAMBRIDGE, Mass. -- The American Academy of Arts and Sciences today announced the election of 196 new Fellows and 17 new Foreign Honorary... Learn more...

LSI announces May symposium: Cancer Insights: Molecules to Medicine

November 8, 2006 - LSI announces May symposium: Cancer Insights: Molecules to Medicine April 20, 2005 ANN ARBOR, Mich.---Top cancer researchers from across the country will discuss their latest findings at the Life Sciences Institute's fourth annual symposium: Cancer... Learn more...

LSI adds top scientists to interdisciplinary faculty

November 7, 2006 - LSI adds top scientists to interdisciplinary faculty April 18, 2005 ANN ARBOR, Mich.---The Life Sciences Institute (LSI) today announced the hiring of six additional faculty members. The new LSI cohort, recruited from across the country, adds to th... Learn more...

2005 Life Sciences Institute/Perrigo Fellows Announced

April 8, 2005 - 2005 Life Sciences Institute/Perrigo Fellows Announced ANN ARBOR, Mich.---The Life Sciences Institute (LSI) of the University of Michigan and the Perrigo Company, a pharmaceutical and nutritional products manufacturer based in Allegan, MI, have awar... Learn more...

An abiding affection for UM branches into science

February 28, 2005 - An abiding affection for UM branches into science Joseph Goldstein met his wife Ellen while they were both studying at the UM law library. "That adds to our affection for UM," said Joe. "I was studying law, and Ellen was studying for... Learn more...

Performance Artist Stelarc Explores Our Prosthetically-Enhanced Future

November 8, 2004 - Performance Artist Stelarc Explores Our Prosthetically-Enhanced Future ANN ARBOR, Mich---Cutting-edge Australian artist Stelarc discussed his ongoing investigations into the obsolescence of the human body in a performance entitled Augmented and Av... Learn more...

Rowena Matthews elected to Institute of Medicine

October 18, 2004 - Rowena Matthews elected to Institute of Medicine Life Sciences Institute faculty member Rowena G. Matthews was elected to The Institute of Medicine of the National Academies October 18, 2004 along with 64 other new members, raising the Institute's t... Learn more...

Life Sciences Institute Research Professor Kun-Liang Guan Receives Faculty Recognition Award

October 5, 2004 - Life Sciences Institute Research Professor Kun-Liang Guan Receives Faculty Recognition Award ANN ARBOR, Mich.---Noted for his brilliant science, Professor Kun-Liang Guan will receive a Faculty Recognition Award from the University of Michigan on Oct... Learn more...

U-M Life Sciences Institute unveils two centers

May 14, 2004 - U-M Life Sciences Institute unveils two centers ANN ARBOR, Mich. -- Director Alan R. Saltiel announced the establishment of two new centers of collaboration within the multidisciplinary Life Sciences Institute this morning during the LSI's Grand Ope... Learn more...

Targeting anthrax: potential drug target identified by Sherman lab

May 8, 2012 -   Targeting anthrax: potential drug target identified by Sherman lab ANN ARBOR, Mich.—Researchers at the University of Michigan have identified new targets for drugs that could potentially treat anthrax, the deadly infection caused by ... Learn more...

One enzyme, two roles: Study of immune cells leads to promising questions related to cancer, obesity and beyond

March 29, 2012 - One enzyme, two roles: Study of immune cells leads to promising questions related to cancer, obesity and beyond Scientists at the Life Sciences Institute (LSI) have illuminated a previously unexplored phase in the complicated life of immune cells, e... Learn more...

Ginsburg lab identifies potential antibiotic alternative with support from the Innovation Partnership

February 17, 2012 - Ginsburg lab identifies potential antibiotic alternative with support from the Innovation Partnership Researchers at the University of Michigan have found a potential alternative to conventional antibiotics that could fight infection with a reduce... Learn more...

Weisman lab uncovers an unexpected link between vesicle membranes and molecular motors

December 13, 2011 - Weisman lab uncovers an unexpected link between vesicle membranes and molecular motors December 14, 2011 -- Drs. Yui Jin, a postdoctoral associate, and Lois Weisman, LSI faculty member and professor of Cell and Developmental Biology in UM’s Me... Learn more...

Yamashita lab identifies two new genes implicated in the regulation of stem cell proliferation

November 11, 2011 - Yamashita lab identifies two new genes implicated in the regulation of stem cell proliferation Yukiko Yamashita, research assistant professor at the Life Sciences Institute and assistant professor of Cell and Development Biology in U-M's Medical Sch... Learn more...

Lim lab collaborates with Korean and U.S. researchers to discover new properties of an important iron complex

November 10, 2011 - Lim lab collaborates with Korean and U.S. researchers to discover new properties of an important iron complex Mi Hee Lim, LSI research assistant professor and assistant professor in the Department of Chemistry of the College of Literature, Science a... Learn more...

Shawn Xu’s lab maps the neural circuits involved in worm movement revealing a surprising complexity and human-like parallels

November 10, 2011 - Shawn Xu’s lab maps the neural circuits involved in worm movement revealing a surprising complexity and human-like parallels Nov. 10, 2011—ANN ARBOR, Mich.—A University of Michigan biologist and his colleagues have found that the s... Learn more...

Skiniotis lab teams up with other top researchers to show never-before-seen detail of major molecular drug target

September 28, 2011 - Vital Protein Complex and Therapeutic Possibilities Revealed Trio of papers describe in unprecedented detail a major molecular target for drugs   September 28, 2011--Three international teams of scientists, led by researchers at the Universit... Learn more...

Skiniotis lab harnesses the power of electron cryo-microscopy to visualize assembling cellular machines

August 26, 2011 - Skiniotis lab harnesses the power of electron cryo-microscopy to visualize assembling cellular machines August, 2011 – Life Sciences Institute professor Georgios Skiniotis and colleagues have obtained for the first time detailed snapshots of... Learn more...

Lim lab publishes on misfolded proteins in Chemical Society Reviews

August 8, 2011 -   Lim lab publishes on misfolded proteins in Chemical Society Reviews August 8, 2011. LSI professor Mi Hee Lim and lab member Alaina S. DeToma published a Tutorial Review in the current issue of Chemical Society Reviews called, “Misfolde... Learn more...

Sherman lab reports on latest work in the area of tirandamycin antibiotics

August 1, 2011 - Sherman lab reports on latest work on tirandamycin antibiotics August, 2011 – Life Sciences Institute professor David Sherman andcolleagues report on their latest work in the area of tirandamycin antibiotics; published in Nature Chemistry. &n... Learn more...

Klionsky lab identifies new proteins required for autophagy

July 28, 2011 - Klionsky lab identifies new proteins required for autophagy July, 2011 – Life Sciences Institute professor Dan Klionsky and colleagues have found that SNARE proteins, a class of proteins previously known for assisting with other vesicle fusion... Learn more...

Rudenko lab solves structure of a synaptic protein implicated in neuropsychiatric disorders

July 5, 2011 - Structure of a complex synaptic protein implicated in neuropsychiatric disorders solved  June, 2011. LSI faculty member Gabrielle Rudenko and her lab have solved the structure of a large complex protein that is central to how synapses ar... Learn more...

Garneau-Tsodikova lab publishes in PNAS on tuberculosis drug resistance

May 31, 2011 - Understanding tuberculosis drug resistance: super drug inactivator revealed   May 31, 2011, ANN ARBOR, Mich. – Researchers at the University of Michigan’s Life Sciences Institute and College of Pharmacy have uncovered how tuberculo... Learn more...

Garneau-Tsodikova lab publishes latest work in Organic & Biomolecular Chemistry on building better antibiotics

May 25, 2011 - Garneau-Tsodikova lab publishes work that reports on building better antibiotics, faster, while also addressing the antibiotic resistance problem   May, 2011 - LSI researcher Sylvie Garneau-Tsodikovaand her colleagues report a complement to th... Learn more...

Xu lab describes how C. elegans senses different kinds of touch, report findings online in Nature Communications

May 18, 2011 - Xu lab describes how C. elegans senses different kinds of touch, report findings online in Nature Communications May 18, 2011--The Caenorhabditis elegans (C. elegans) is the very long name of a very small creature, and one of the most commonly used ... Learn more...

Garneau-Tsodikova lab reports on new findings related to Alzheimer's disease in MedChemComm

May 4, 2011 - Garneau-Tsodikova lab publishes work in MedChemComm reporting on a new class of compounds that inhibit the enzyme implicated in the development of Alzheimer’s disease   May 4, 2011 - LSI research assistant professor Sylvie Garneau-Tsodik... Learn more...

Joint discovery on diabetes highlights how great science moves forward through teamwork

April 25, 2011 -  Joint discovery on diabetes highlights how great science moves forward through teamwork April, 2011. In a study published recently in Nature Cell Biology, LSI director Alan Saltiel and colleagues in the labs of LSI professors David Ginsburg, and... Learn more...

Ye lab reports latest findings in the Journal of Neuroscience on how neurons develop

March 15, 2011 - Ye lab reports latest findings in the Journal of Neuroscience on how neurons develop March, 2011. Neurons are the building blocks of the brain. Our senses, thoughts, and memories all depend on properly developed neurons and the connections among the... Learn more...

Lim lab reports new findings on Alzheimer’s in PNAS

December 6, 2010 - Unraveling Alzheimer's: Simple small molecules could untangle complex disease New molecular tools developed in the lab of assistant professor Mi Hee Lim show promise for "cleansing" the brain of amyloid plaques, implicated in A... Learn more...

Morrison lab identifies protein essential for cell division in blood-forming stem cells; work published in Nature

December 2, 2010 - Morrison lab identifies protein essential for cell division in blood-forming stem cells University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-formi... Learn more...

Smith lab reveals structure of protein related to heart and nervous system health; paper published in PNAS

November 16, 2010 -  Structure of a protein related to heart and nervous system health revealed. May lead to smarter drug design, better understanding of a genetic disorder of the cardiovascular system   ANN ARBOR, Mich. -- University of Michigan researchers ha... Learn more...

Morrison lab finds that melanoma does not conform to cancer stem cell model; work published in Cancer Cell

November 16, 2010 - More evidence that melanoma does not conform to the cancer stem cell model   ANN ARBOR, Mich. --- University of Michigan researchers have determined that most types of melanoma cells can form malignant tumors, providing new evidence that the d... Learn more...

Maillard lab develops a new method to reduce graft-versus-host-disease after bone marrow transplantation

October 7, 2010 - Maillard lab develops a new method to reduce graft-versus-host-disease after bone marrow transplantation, research recently published Bone marrow transplantation can cure patients with leukemia and other cancers even when the disease is resistant to... Learn more...

Lin lab gets to the heart of how niacin works and points to a new pathway

October 6, 2010 - Lin lab gets to the heart of how niacin works and points to a new pathway High blood lipids are a leading risk factor for developing heart disease, which is the leading cause of death in the United States. Approximately one of every six adult Amer... Learn more...

Ginsburg lab publishes findings in PNAS on mutation during gene targeting

September 24, 2010 -  Findings show that spontaneous mutations arising during gene targeting may be a frequent, underappreciated, occurrence  The use of genetically altered mice by gene targeting is widespread in biomedical research. Gene targeting common... Learn more...

Tesmer lab reveals first complete crystal structure of a G protein-coupled receptor kinase

August 26, 2010 - Tesmer lab reveals first complete crystal structure of a G protein-coupled receptor kinase G protein-coupled receptors (GPCRs) constitute a large protein family of receptors that are able to sense molecules outside of the cell, such as light, odor... Learn more...

Kim lab shows the diversity of how genes are transcribed during development, work published in Science

August 18, 2010 - Kim lab shows the diversity of how genes are transcribed during development, work published in Science Although the full genome of C. elegans has been available for more than 10 years, only a portion of the full-length messenger RNAs (mRNAs) and the... Learn more...

Decoding an encoded gene: Xu lab sheds light on the mechanotransduction channels responsible for hearing, touch

August 12, 2010 - Decoding an encoded gene: Xu lab sheds light on the mechanotransduction channels responsible for hearing, touch Mechanotransduction channels mediate a number of our senses, such as hearing, touch and proprioception (a sense of one’s own body m... Learn more...

Outfoxing FoxO: Hu lab discovers a new protein and how it acts upon FoxO

July 7, 2010 - Outfoxing FoxO: Hu lab discovers a new protein and how it acts upon FoxO     LSI Research Assistant Professor Patrick Hu and colleagues have discovered and characterized EAK-7, a novel conserved protein that acts in parallel to insulin-li... Learn more...

Smith lab reveals first crystal structure of any protein in the Bunyaviridae virus family

June 16, 2010 - First crystal structure of any protein in the Bunyaviridae virus family revealed LSI research professor Janet Smith and colleagues have solved the structure of the nucleocapsid protein from Rift Valley fever virus (RVFV), so named for the region of ... Learn more...

A Tale of Two Molecules: Gestwicki Lab makes progress in understanding how Hsp-70 protein works

June 10, 2010 -  A Tale of Two Molecules: Two Small Molecules Lead the Way to Understanding Hsp-70 Protein Complex LSI Research Assistant Professor Jason Gestwicki and colleagues have made significant progress in beginning to understand how bacterial heat-shock p... Learn more...

Xu lab discovers something new about C. elegans, paper in Nature Neuroscience

May 3, 2010 - A taste of light: new findings reveal a pathway that allows eyeless worms to "see"  Though it might seem counterintuitive, the eyeless C. elegans roundworm just might hold important clues to understanding human vision and the causes o... Learn more...

Sherman lab aims to develop something completely new in the field of natural products (View Slideshow)

March 29, 2010 -  The Elegance of a Tunicate David Sherman and his lab aim to develop something completely new in the field of natural products Photos from Dr. Sherman’s Dives To view a slideshow, click on the photo. image 2 | image 3 | image 4 |... Learn more...

Kondrashov and Kondrashov study shows the complexities of evolution at the mitochondrial tRNA level

February 24, 2010 - Kondrashov and Kondrashov study shows the elegant complexities of evolution   Collaborating with his son Fyodor Kondrashov, Centre for Genomic Regulation, Barcelona, Spain, and other colleagues, LSI Research Professor Alexey Kondrashov pu... Learn more...

Inoki lab sheds light on how ROS inhibits mTOR function

February 17, 2010 - Inoki lab sheds light on how ROS inhibits mTOR function In a paper published online and in the February 23, 2010 issue of PNAS, LSI faculty member Ken Inoki and colleagues demonstrate that reactive oxygen species (ROS) inhibits (mammalian target of ... Learn more...

Smith lab reveals crystal structures of small molecules, expands understanding of potential therapeutics

January 25, 2010 - Examining the Crystal Structures of Dehydratase Domains from the Curacin A polyketide synthase   In a paper published in the January, 2010 edition of Structure, Janet Smith and colleagues present an examination of crystal structures of the... Learn more...

Garneau-Tsodikova lab develops a new, faster method for generating novel, more effective antibiotics

January 7, 2010 - Outsmarting bacteria: Garneau-Tsodikova Lab develops a new, faster method for generating novel, more effective antibiotics   It’s in the news on a regular basis: antibiotics are losing their efficacy against bacteria that have built up re... Learn more...

U-M study reveals lack of genetic diversity in the most widely used human embryonic stem cell lines

December 16, 2009 - U-M study reveals surprising lack of genetic diversity in the most widely used human embryonic stem cell lines   By Jim Erickson News Service   ANN ARBOR, Mich.---The most widely used human embryonic stem cell lines lack genetic divers... Learn more...

LSI investigator Noah Rosenberg and team use bioinformatics to shed light on the genetics and history of Jewish sub-populations

December 9, 2009 -  LSI investigator Noah Rosenberg and team use bioinformatics to shed light on the genetics and history of Jewish sub-populations   LSI faculty Noah Rosenberg and his team published the results of a paper in the online journal, BMC Genetic... Learn more...

Carroll lab pinpoints a new antioxidant system that protects single cysteines, which could lead to new antioxidant therapies

November 20, 2009 - Saving the single cysteine: new antioxidant system found By Nancy Ross-Flanagan Watch the video width="425" height="344">   ANN ARBOR, Mich.---We've all read studies about the health benefits of having a li... Learn more...

Lim lab develops hybrid molecular tools to understand, treat Alzheimer's

November 3, 2009 -  Hybrid molecules show promise for exploring, treating Alzheimer's   By Nancy Ross-Flanigan News Service     ANN ARBOR, Mich.---One of the many mysteries of Alzheimer's disease is how protein-like snippets called amyloid-beta pe... Learn more...

Sherman lab in LSI collaborates with Montgomery lab in LSA to engineer a new biological catalyst

October 12, 2009 - Sherman lab in LSI collaborates with Montgomery lab in LSA to engineer a new biological catalyst and new class of antibiotic molecules The laboratories of  LSI faculty member David Sherman and LSA Chemistry faculty member John Montgomery publis... Learn more...

LSI Klionsky links cell behavior and the key to longer life

October 6, 2009 - Self-Destructive Behavior in Cells May Hold Key to a Longer Life Daniel Klionsky of the U-M Life Sciences Institute was highlighted in a New York Times Science article on Tuesday, Oct 7, 2009.   Klionsky’s work highlights how self-dest... Learn more...

U-M researchers find gene that protects high-fat-diet mice from obesity

September 2, 2009 - U-M researchers find gene that protects high-fat-diet mice from obesity ANN ARBOR, Mich. --- University of Michigan researchers have identified a gene that acts as a master switch to control obesity in mice. When the switch is turned “off,&quo... Learn more...

New genomic study supports out-of-Africa theory of modern human origins

October 1, 2009 - New genomic study supports out-of-Africa theory of modern human origins http://www.pnas.org/content/106/38/16057.full... Learn more...

New chemical tools are poised to help LSI scientists explore the roles oxidized cysteine residues might play in biology

October 6, 2009 - New chemical tools are poised to help LSI scientists explore the roles oxidized cysteine residues might play in biology Chemical and Engineering News: [link]  ... Learn more...

LSI Faculty member Noah Rosenberg and Colleagues Determine Native Americans Descended From A Single Ancestral Group

May 1, 2009 - LSI Faculty member Noah Rosenberg and Colleagues Determine Native Americans Descended From A Single Ancestral Group LSI Faculty Member Noah Rosenberg and an international team of scientists have uncovered DNA evidence that provides new insight into ... Learn more...

LSI faculty member Kate Carroll featured in Cell's monthly podcast series

March 26, 2009 - LSI faculty member Kate Carroll featured in Cell's monthly podcast series LSI faculty member Kate Carroll was recently interviewed for a Cell Press podcast about her study that was recently published in the Chemistry and Biology Journal. In this int... Learn more...

Extending the lifetime of AIDS drugs: LSI lab synthesizes modified compound that may increase effectiveness

January 21, 2009 - Extending the lifetime of AIDS drugs: LSI lab synthesizes modified compound that may increase effectiveness One of the challenges of modern anti-HIV therapy is the susceptibility of the drugs to degradation by the liver. To protect one of these co... Learn more...

Morrison team reports that melanoma spawns tumors with deadly efficiency.

December 3, 2008 - Morrison team reports that melanoma spawns tumors with deadly efficiency. ANN ARBOR, Mich.--- One of the most promising new ideas about the causes of cancer, known as the cancer stem-cell model, must be reassessed because it is based largely on evid... Learn more...

LSI faculty member David Sherman and multidisciplinary team announces identification of new drug target in fight against anthrax

October 20, 2008 - LSI facutly member David Sherman and multidisciplinary team announces identification of new drug target in fight against anthrax A multidisciplinary research effort based at the University of Michigan Life Sciences Institute, U.S. Department of Ener... Learn more...

New study led by LSI faculty member Sean Morrison uncovers new links between stem cells, aging and cancer

October 17, 2008 - New study led by LSI faculty member Sean Morrison uncovers new links between stem cells, aging and cancer ANN ARBOR, Mich.--- Four genes previously implicated in the control of cancer have been shown by University of Michigan scientists to play key ... Learn more...

Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find

October 15, 2008 - Stem-cell sentry sounds the alarm to maintain balance between cancer and aging, U-M researchers find Like a sentry guarding the castle walls, a molecular messenger inside adult stem cells sounds the alarm when it senses problems that could allow the... Learn more...

Light-sensing worms provide a new tool for the study of vision and eye disease

July 7, 2008 - Light-sensing worms provide a new tool for the study of vision and eye disease The tiny eyeless C. elegans roundworm, one of the most widely used animals in biological research, can detect flashes of light and responds to them by quickly wriggling a... Learn more...

Secrets of cellular signaling shed light on new cancer stem cell therapies

April 9, 2008 - Secrets of cellular signaling shed light on new cancer stem cell therapies By revealing the inner workings of a common cell-to-cell signaling system, University of Michigan biologists have uncovered new clues about mysterious and contentious creatur... Learn more...

Carroll and colleagues develop new chemical probe to profile redox-regulated proteins

March 17, 2008 - Carroll and colleagues develop new chemical probe to profile redox-regulated proteins LSI faculty member Kate S. Carroll and research partners have published a new paper titled "A chemical approach for detecting sulfenic acid-modified proteins ... Learn more...

Klionsky and colleagues publish new autophagy findings in Nature

February 28, 2008 - Klionsky and colleagues publish new autophagy findings in Nature LSI faculty member Daniel J. Klionsky and research partners have published a new paper titled "Autophagy fights disease through cellular self-digestion" in the most recent ed... Learn more...

U-M researchers release most detailed global study of genetic variation

February 20, 2008 - U-M researchers release most detailed global study of genetic variation University of Michigan scientists and their colleagues at the National Institute on Aging have produced the largest and most detailed worldwide study of human genetic variation,... Learn more...

U-M Researchers Identify Cells That Cause Nervous System Disease

February 4, 2008 - U-M Researchers Identify Cells That Cause Nervous System Disease Two teams of University of Michigan researchers have tracked down the cells responsible for neurofibromatosis type 1, a disfiguring, incurable condition and one of the most common here... Learn more...

LSI researchers reveal missing link in a heart disease pathway

December 20, 2007 - LSI researchers reveal missing link in a heart disease pathway University of Michigan scientists and their colleagues have helped characterize a previously unknown link in the chain of biochemical reactions implicated in some forms of heart disease.... Learn more...

LSI faculty Noah Rosenberg featured in Science News for Siberia-Americas genetic link

December 5, 2007 - LSI faculty Noah Rosenberg featured in Science News for Siberia-Americas genetic link LSI faculty member Noah Rosenberg was featured in Science News for his recent joint publication in PLoS Genetics on the genetic link between Siberia and the Americ... Learn more...

Noah Rosenberg interviewed about new genetic link found between Siberia and native peoples of North America

November 30, 2007 - Noah Rosenberg interviewed about new genetic link found between Siberia and native peoples of North America From the Alaska Public Radio Network website: A new study finds a genetic link for many Native people in North America with certain popu... Learn more...

Sean Morrison interviewed on WJR about new stem cell discoveries

November 21, 2007 - Sean Morrison interviewed on WJR about new stem cell discoveries LSI faculty and director of the Center for Stem Cell Biology is interviewed on News/Talk 760 WJR about stem cell discoveries published earlier this week. Listen to the interview on wj... Learn more...

Comment on breaking research in Cell and Science

November 20, 2007 - Comment on breaking research in Cell and Science November 20, 2007 - This research seems to be very well done and follows on the heels of similar work by the Yamanaka laboratory in mouse cells that was independently confirmed by other laboratories... Learn more...

U-M biochemists add new molecular weapon to their arsenal

November 8, 2007 - U-M biochemists add new molecular weapon to their arsenal November 8, 2007 - University of Michigan researchers have acquired a new molecular tool that could help them transform a toxin from coral-reef bacteria into a next-generation cancer drug. ... Learn more...

U-M scientists find new causes for neurodegeneration

October 24, 2007 -  U-M scientists find new causes for neurodegeneration October 23, 2007 - Diseases that cause neurons to break-down, such as Alzheimer's, Multiple Sclerosis and Creutzfeldt-Jakob disease (Mad Cow Disease), continue to be elusive to scientists an... Learn more...

U-M researchers dispute widely held ideas about stem cells

August 29, 2007 - U-M researchers dispute widely held ideas about stem cells How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? For more than three decades, many scientists have argued that the "immortal stran... Learn more...

LSI team identifies gene that regulates blood-forming fetal stem cells

July 26, 2007 - LSI team identifies gene that regulates blood-forming fetal stem cells In the rancorous public debate over federal research funding, stem cells are generally assigned to one of two categories: embryonic or adult. But that's a false dichotomy and a... Learn more...

Gene discovery aids understanding of common inherited neurological disorder

June 29, 2007 - Gene discovery aids understanding of common inherited neurological disorder Clues from mice and yeast identify a new form of Charcot-Marie-Tooth disorder in people and point the way to genetic testing Scientists have identified the gene respons... Learn more...

LSI faculty Jiandie Lin featured in Nature

May 23, 2007 - LSI faculty Jiandie Lin featured Nature May 24, 2007 - Jiandie Lin is featured twice in this month's issue of Nature for his discoveries related to the PGC-1α protein and its impact on circadian rhythms. Download the profile of Lin and hi... Learn more...

LSI faculty Patrick Hu mentioned in ScienceNOW Daily News

May 3, 2007 - LSI faculty Patrick Hu mentioned in ScienceNOW Daily News May 2, 2007 - Patrick Hu is cited in a recent ScienceNOW Daily News article on the discovery of a longevity gene in the roundworm C. elegans.Read the article... Learn more...

New research from Lin Lab - A rhythm runs through it

May 2, 2007 - A rhythm runs through it Most life on earth, whether simple or complex, flows with the universal hum of circadian rhythms. Our sleeping, eating, and the way we burn energy are all governed by the ticking of our body clocks in relation to light ... Learn more...

Potential therapeutic applications of autophagy

April 10, 2007 - Potential therapeutic applications of autophagy April 2007 - LSI faculty Jason E. Gestwicki and Daniel J. Klionsky discuss their research in the recent issue of Nature Reviews Drug Discoveries.Read the abstractLink to article forthcoming... Learn more...

Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division

February 8, 2007 - Asymmetric Inheritance of Mother Versus Daughter Centrosome in Stem Cell Division January 26, 2007 LSI faculty member Yukiko Yamashita and colleagues recently published a report on adult stem cells in Science. Read the abstract or login to r... Learn more...

When good cells go bad by the fat company they keep

January 3, 2007 - When good cells go bad by the fat company they keep January 2, 2007 ANN ARBOR, Mich.---Macrophages are normally good cells and key players in the immune system to fight off foreign invaders. But when a macrophage is presented with a high-fat ... Learn more...

Turning Green Gunk to Gold, Anti-Cancer Gold

January 2, 2007 - Turning Green Gunk to Gold, Anti-Cancer Gold December 21, 2006 ANN ARBOR, Mich.---Combining synthetic chemistry techniques with a knowledge of the properties and actions of enzymes, scientists have been able to produce an exciting class of anti... Learn more...

Constructing a new cell structure featured on the cover of the Dec. 18 Journal of Cell Biology

December 19, 2006 - How to make a cell that takes out your trash December 20, 2006 ANN ARBOR, Mich.--- If only we could coax our cells into being better housekeepers, vigilant about throwing out damaged or unneeded parts, our bodies would probably run a lot m... Learn more...

Tiny Worm Provides Model for the Genetics of Nicotine Dependence

November 6, 2006 - Tiny Worm Provides Model for the Genetics of Nicotine Dependence November 6, 2006, ANN ARBOR, Mich. - The unassuming C. elegans nematode worm, a 1-millimeter workhorse of the genetics lab, has the same genetic susceptibility to nicotine dependence... Learn more...

Mapping Genetic Diseases

October 22, 2006 - Mapping Genetic Diseases One small snip from man; one giant leap for the genome October 23, 2006, ANN ARBOR, Mich.---Snips from the DNA of only 270 people from just four world locations provide a reliable map of genetic disease variations in the ... Learn more...

How Cancers Metastasize

September 27, 2006 -  How Cancers Metastasize September 28, 2006, ANN ARBOR, Mich--- A new finding from the laboratory of Stephen Weiss at the University of Michigan provides important insights into cancer cells’ most deadly characteristic -- their ability to invade... Learn more...

Turning Off A Tumor Signal

September 7, 2006 - Turning Off A Tumor Signal ANN ARBOR, Mich.— The discovery of new cellular machinery leading to tumor cell growth in colorectal cancers points to a possible treatment. Researchers at the Life Sciences Institute at the University of Michigan r... Learn more...

Ringing in New Antibiotic Drugs

September 6, 2006 - Ringing in New Antibiotic Drugs Ann Arbor, Mich. and Minneapolis, Minn. -- When infections like Strep and tuberculosis become resistant to antibiotics, patients are in trouble. Infections become more difficult to treat as disease-causing bugs muta... Learn more...

Older Stem Cells Actively Shut Themselves Down

August 31, 2006 - Older Stem Cells Don't Just Wear Out, They Actively Shut Themselves Down Sept. 1, 2006, ANN ARBOR, Mich.---The natural consequences of growing old include slower wound-healing and a brain that makes fewer new neurons because old tissues have less ... Learn more...

Michigan Team Singles Out Cancer Stem Cells for Attack

May 25, 2006 - Michigan team singles out cancer stem cells for attack May 25, 2006, ANN ARBOR, Mich--- Close on the heels of the discovery that cancer has its own rejuvenating stem cells, a University of Michigan research team has found a way to distinguish thes... Learn more...

Expanding waistlines triggered by your genes

November 6, 2006 - Expanding waistlines triggered by your genes May 5, 2006 ANN ARBOR, Mich---A gene that degrades the body's collagen infrastructure has been shown to make fat cells fatter and expand girth. Excess fat is stored in white adipose tissue, the primary ... Learn more...

Rosenberg and Xu Receive Prestigious Fellowship

February 22, 2006 - Rosenberg and Xu Receive Prestigious Fellowship February 22, 2006, ANN ARBOR, Mich--- LSI Research Assistant Professors Noah Rosenberg and Shawn Xu were among five recipients at UM honored with Sloan Research Fellowships. These awards from the Al... Learn more...

Modeling Cells' Messengers

December 2, 2006 - Modeling Cells' Messengers December 9, 2005 Humans have millions of cells to conduct the business of the body. By exchanging chemical signals, cells "talk" to each other to perform functions like regulating blood pressure, converting food into ... Learn more...

Human Genetic Diversity Supports "Out of Africa" Model

October 15, 2005 - Human Genetic Diversity Supports "Out of Africa" Model Monday, October 17, 2005 ANN ARBOR, Mich. -- Small groups of settlers expanding outward from Africa over time are the most likely progenitors of the modern human population worldwide, accordi... Learn more...

Janet Smith Uncovers Structure of Protein Involved in Vitamin B6 Biosynthesis

November 6, 2006 - Janet Smith Uncovers Structure of Protein Involved in Vitamin B6 Biosynthesis July 29, 2005 ANN ARBOR, Mich---LSI research professor Janet Smith has elucidated the structure of an enzyme involved in the biosynthesis of vitamin B6, one of the many v... Learn more...

Anuj Kumar Featured in Genomic Technology Magazine

November 6, 2006 - Anuj Kumar Featured in Genomic Technology Magazine March 15, 2005 Model Organism Marathon If you've been in this field long enough, you've probably heard -- or perhaps contributed to -- the grumbling by now. Researchers who traffic in plant and an... Learn more...

Life Sciences Institute Research Professor Daniel J. Klionsky Examines the Cell's Housekeeping Habits

November 6, 2006 - Life Sciences Institute Research Professor Daniel J. Klionsky Examines the Cell's Housekeeping Habits November 4, 2004 ANN ARBOR, Mich---The cells of higher organisms have an internal mechanism for chewing up and recycling parts of themselves, part... Learn more...

Strep disrupts blood clotting to infect humans

November 6, 2006 - Strep disrupts blood clotting to infect humans August 26, 2004 ANN ARBOR, Mich.---University of Michigan researchers have captured a glimpse of the endless arms race between infectious agents and the human immune system in a bacterium that uses a m... Learn more...