Press Releases

  1. November 1, 2016
    There’s a transcription factor known as NF-kappaB, which is part of a cellular signaling pathway that goes awry in many diseases from autoimmune disorders to cancer. “NF-kappaB is an important one,” says Anna Mapp, Ph.D., a faculty member at the University of Michigan Life Sciences Institute. “It’s master transcription factor that controls many different cellular decisions.”
  2. October 17, 2016
    Two U-Michigan faculty elected to prestigious National Academy of Medicine, including LSI Director Roger D. Cone, Ph.D.
  3. October 17, 2016
    A transcription factor known as Snail1 can act as a “molecular bypass” that diminishes the natural tumor suppressing action of a gene called p53 in breast cancer patients, a group of scientists led by the University of Michigan and China Pharmaceutical University have found.
  4. September 22, 2016
    by Julie Halpert   David Sherman, Ph.D., does much of his field work underwater, diving as deep as 130 feet to collect microbial samples that can become the basis for new drugs to treat infectious diseases and cancers.
  5. September 15, 2016
    Researchers at the University of Michigan Life Sciences Institute are breaking new ground in scientists’ quest to develop drugs that can target DNA transcription, which is dysregulated in a variety of diseases from cancer to diabetes.
  6. July 19, 2016
    Researchers have revealed the molecular structure of a protein produced by the Zika virus that is thought to be involved in the virus’s reproduction and its interaction with a host’s immune system. The results provide scientists around the globe with new information about the NS1 protein’s role in Zika virus infections, and expands scientists’ understanding of the flavivirus family, which also includes dengue, West Nile and yellow fever.
  7. June 30, 2016
    A related group of single-celled parasites are responsible for an array of debilitating and deadly tropical diseases including African sleeping sickness, leishmaniasis and Chagas’ disease. A lack of effective medicines and vaccines, as well as growing resistance to current therapies have spurred researchers to search for new ways to fight the pathogens.
  8. June 16, 2016
    Roger D. Cone, Ph.D., will serve as the new Mary Sue Coleman Director of the University of Michigan Life Sciences Institute, effective Sept. 1. His appointment was approved June 16 by the Board of Regents.
  9. June 16, 2016
    For simple organisms, it is vital to be able to recognize dangerous pH levels in the environment. Both highly acidic and highly basic substances can be toxic if ingested, and they can injure sensitive skin. While the molecular mechanisms for acid sensation have been well documented, far less is known about alkali sensing. A new study by researchers at the University of Michigan Life Sciences Institute and collaborators in China identified a new type of alkaline sensor in nematodes.
  10. June 2, 2016
    Last week, health officials announced the first case in the U.S. of E. coli resistant to colistin, a “last resort” antibiotic.

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