Wenjing Wang Lab

Our Research

Our lab studies optogentic technologies for protein detection and manipulation in living cells.

We will applying cutting-edge protein engineering methods, such as directed evolution, to improve the dynamic range and overall performance of light-sensitive proteins, and to harness them for detection and manipulation of important biochemical events. Our goal is to expand the optogenitics toolbox with widespread utility across multiple subfields of cell biology and neuroscience.

The lab will be joing the LSI June 1, 2018.

About Wenjing Wang

Assistant Research Professor

 

 

I am trained as a chemical biologist and am deeply interested in developing novel molecular technologies for cell biology.

Recent Publications

Kim M.W.*, Wang, W.*,Sanchez, M. I, Coukos, R., von Zastrow, M., Ting, A. Y. “ Time-Gated Detection of Protein-Protein Interactions with Transcriptional Readout.” eLife 6, e30233 (2017)

Wang, W., Wildes, C. P., Pattarabanjird, T., Sanchez, M. I.; Glober, G.F., Matthews, G. A., Tye, K. M., Ting, A. Y. “ A Light- and Calcium-Gated Transcription Factor for Imaging and Manipulation of Activated Neurons.” Nat Biotech 35, 864-871 (2017)

Assar, Z., Nossoni, Z., Wang, W., Santos, E. M., Kramer, K., McCornack, C., Vasileiou, C., Borhan, B., and Geiger, J. H. Domain-Swapped Dimers of Intracellular Lipid-Binding Proteins: Evidence for Ordered Folding Intermediates. Structure 24, 1590-1598(2016)