Georgios Skiniotis

Our Research

Our scientific presence evolves around the 3D visualization of protein nanomachines and the deconvolution of mechanistic aspects of their operation. This has been primarily accomplished through the application of molecular electron microscopy (cryo-EM and negative stain EM), currently the only technique that allows direct visualization of biological complexes at the molecular level.

Meet our team: www.lsi.umich.edu/skiniotis-lab/lab-members

Our technology platform: www.lsi.umich.edu/cryo-em

About Georgios Skiniotis

Specialties:
  • structural biology
  • cryo-EM
  • cell surface receptors

Georgios (a.k.a. Yiorgo) Skiniotis is a Pew Scholar of Biomedical Sciences and an Associate Professor of Biological Chemistry at the University of Michigan Medical School.

Recent Publications

Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G. (2014). Structure of a modular polyketide synthase. Nature.

Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis, G. (2014). Structural rearrangements of a polyketide synthase module during its catalytic cycle. Nature.

Shukla AK, Westfield GH, Xiao K, ... Kobilka BK✚, Skiniotis G✚ & Lefkowitz RJ✚. (2014). Visualization of arrestin recruitment by a G Protein-Coupled Receptor. Nature.