The parent labs works to understand how cells detect and respond to external chemotactic signals that are detected by GPCRs, and, in particular, how the spatial and temporal relay of chemotactic signals between cells impact single and group cell migration in the context of inflammation and cancer metastasis.
- cancer biology
- chemotactic signaling
Carole Parent's research focuses on understanding how cells detect and respond to external chemotactic signals and, in particular, how the spatial and temporal relay of chemotactic signals between cells impacts single and group cell migration. Her work has implications in a variety of processes, including inflammation, tissue repair and cancer metastasis.
Szatmary AC, Nossal R, Parent CA, Majumdar R. Modeling Neutrophil Migration in Dynamic Chemoattractant Gradients: Assessing the Role of Exosomes During Signal Relay.Mol Biol Cell. 2017 Sep 27. pii: mbc.E17-05-0298. doi: 10.1091/mbc.E17-05-0298. [Epub ahead of print] PubMed PMID: 28954858