Publications
2011
Takahashi YH, Westfield GH, Oleskie AN, Trievel RC, Shilatifard A, and Skiniotis G. Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human. PNAS 2011 Dec 7. [Epub ahead of print]
Thompson AD, Bernard SM, Skiniotis G, Gestwicki JE. Visualization and functional analysis of the oligomeric states of Escherichia coli heat shock protein 70 (Hsp70/DnaK). Cell Stress Chaperones 2011 Nov 11. [Epub ahead of print]
Westfield G, Rasmussen SGF, Su M, Dutta S, DeVree BT, Chung KY, Calinski D, Velez-Ruiz G, Oleskie AN, Pardon E, Chae PS, Liu T, Li S, Woods Jr. VL, Steyaert J, Kobilka BK, Sunahara RK, Skiniotis G. Structural flexibility of the Gαs a-helical domain in the b2-adrenoceptor Gs complex. PNAS 2011 Sept 13 [Epub ahead of print].
Strunk BS, Loucks CR, Su M, Vashisth H, Cheng S, Schilling J, Brooks CL 3rd, Karbstein K, Skiniotis G. Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. Science 2011 Aug 11 [Epub ahead of print]. PubMed Link; Read it.
Rasmussen SGF, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah STA, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK & Kobilka BK. Crystal structure of the b2 adrenergic receptor–Gs protein complex. Nature 2011 (published online July 19; doi:10.1038/nature10361) PubMed Link
Gu L, Eisman EB, Dutta S, Franzmann TM, Walter S, Gerwick WH, Skiniotis G & Sherman DH. Tandem Acyl Carrier Proteins in the Curacin Biosynthetic Pathway: Promotion of Consecutive Multienzyme Reactions with a Synergistic Effect. Angewandte Chemie 2011 Mar 14;50(12):2795-8. PubMed Link
Lupardus PJ*, Skiniotis G*, Rice AJ, Thomas C, Fischer S, Walz T, and Garcia KC. Structural snapshots of full-length Jak1, a transmembrane gp130/IL-6/IL-6Ra cytokine receptor complex, and the receptor-Jak1 holocomplex. (*: equal contribution) Structure 2011 Jan 12;19(1):45-55. PubMed Link
1999-2008
Skiniotis G*, Lupardus P*, Martick M, Walz T & Garcia KC. Molecular architecture of a full-length cytokine receptor transmembrane signaling complex: the quaternary assembly of CNTF, CNTF-Ra, LIF-R and gp130. (*: equal contribution) Molecular Cell 2008 Sep 5;31(5):737-48. PubMed Link
Meijers R, Puettmann-Holgado R, Skiniotis G, Liu J-H, Walz T, Schmucker D & Wang J-H. Structural basis of Dscam isoform specificity. Nature 2007 Sep 27; 449 (7161):487-91. PubMed Link
Skiniotis G, Moazed D and Walz T. Acetylated histone-tail peptides induce structural rearrangements in the RSC chromatin remodeling complex. J Biol Chem. 2007 July 20;282(29):20804-8. PubMed Link
Ruch C*, Skiniotis G*, Steinmetz M, Walt T & Ballmer-Hofer K. Structure of a VEGF / VEGF receptor complex as determined by EM. (*: equal contribution) Nature Struct Mol Biol. 2007 Mar; 14(3):249-250. PubMed Link
Skiniotis G, Boulanger MJ, Garcia KC, and Walz T. Signaling conformations of the tall cytokine receptor gp130 when in complex with IL-6 and IL-6 receptor. Nature Struct Mol Biol. 2005 Jun;12(6):545-51. PubMed Link
Santarella RA, Skiniotis G, Goldie KN, Tittmann P, Gross H, Mandelkow EM, Mandelkow E, and Hoenger A. Surface-decoration of microtubules by human tau. J Mol Biol. 2004 Jun 4;339(3):539-53. PubMed Link
Skiniotis G, Cochran JC, Muller J, Gilbert SP, and Hoenger A. Modulation of kinesin binding by the C-termini of tubulin. EMBO J. 2004 Mar 10;23(5):989-99. PubMed Link
Bringmann H, Skiniotis G, Spilker A, Kandels-Lewis S, Vernos I, Surrey T. A kinesin-like motor inhibits microtubule dynamic instability. Science 2004 Mar 5;303(5663):1519-22. PubMed Link
Skiniotis G, Surrey T, Altmann S, Gross H, Song YH, Mandelkow E, Hoenger A. Nucleotide-induced conformations in the neck region of dimeric kinesin. EMBO J. 2003 Apr 1;22(7):1518-28. PubMed Link
Wendt TG, Volkmann N, Skiniotis G, Goldie KN, Muller J, Mandelkow E, Hoenger A. Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd. EMBO J. 2002 Nov 15;21(22):5969-78. PubMed Link
Velegraki A, Kambouris ME, Skiniotis G, Savala M, Mitroussia-Ziouva A, Legakis NJ. Identification of medically significant fungal genera by polymerase chain reaction followed by restriction enzyme analysis. FEMS Immunol Med Microbiol. 1999 Apr;23(4):303-12. PubMed Link