Wang, Y., Cesena, T., Ohnishi, Y., Burger-Caplan, R., Lam, V., Kirchhoff, P., Larsen, S., Larsen, M., Nestler, E., Rudenko, G. (2012).
Small molecule screening identifies regulators of the transcription factor DeltaFosB.
ACS Chemical Neuroscience, in press.
Chen, F., Venugopal, V., Murray, B, Rudenko, G. (2011).
The structure of neurexin 1alpha reveals features promoting a role as synaptic organizer.
Structure 19(6):779-89.
PubMed Link
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Commentary: Structure (2011) 19(6):749-50.
Ren, G., Rudenko, G., Ludtke, S.J., Deisenhofer, J., Chiu, W., Pownall, H.J. (2010).
Model of Human Low Density Lipoprotein and Bound Receptor Based on Cryo-EM.
Proc. Natl. Acad. Sci. USA 107(3):1059-64.
PubMed Link
Huang, S., Henry, L., Ho, Y.K., Pownall, H.J., Rudenko G. (2010).
Mechanism of LDL Binding and Release Probed by Structure-Based Mutagenesis of the LDL receptor.
J. Lipid Res. 51(2): 297-308.
PubMed Link
Shen, K. C., Kuczynska, D.A., Wu, I.J., Murray, B.H., Sheckler, L.R., & Rudenko, G. (2008).
Regulation of neurexin 1beta tertiary structure and ligand binding through alternative splicing.
Structure, 16, 422-431.
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Jorissen, H. J., Ulery, P.G., Henry, L., Gourneni, S., Nestler, E.J., & Rudenko, G. (2007).
Dimerization and DNA-binding properties of the transcription factor DeltaFosB.
Biochemistry, 46(28), 8360-72.
PubMed Link
Sheckler, L. R., Henry, L., Sugita S., Südhof, T.C., & Rudenko, G. (2006).
Crystal structure of the second LNS/LG domain from neurexin 1alpha: Ca2+-binding and the effects of alternative splicing.
Journal of Biological Chemistry, 281, 22896-905.
PubMed Link
Ulery, P. G., Rudenko, G., & Nestler, E. J.(2006).
Regulation of Delta FosB stability by phosphorylation.
Journal of Neuroscience, 26, 5131-5142.
PubMed Link
Rudenko, G., Henry, L., Vonrhein, C., Bricogne, G., & Deisenhofer, J. (2003).
'MAD'ly phasing the extracellular domain of the LDL receptor: A medium-sized protein, large tungsten clusters and multiple non-isomorphous crystals.
Acta Crystallographica Section D - Biological Crystallography, 59, 1978-1986.
PubMed Link
Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M. S., Goldstein, J. L., & Deisenhofer, J. (2002).
Structure of the LDL receptor extracellular domain at endosomal pH.
Science, 298, 2353-2358.
PubMed Link
Commentary: Science (2002) 298:2337-9
Rudenko, G., Hohenester, E., & Muller, Y. A. (2001).
LG/LNS domains: Multiple functions - One business end?
Trends in Biochemical Sciences, 26, 363-368.
PubMed Link
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The structure of the ligand-binding domain of neurexin I beta: Regulation of LNS domain function by alternative splicing.
Cell, 99, 93-101.
PubMed Link
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The atomic model of the human protective protein cathepsin A suggests a structural basis for galactosialidosis.
Proceedings of the National Academy of Sciences of the USA, 95, 621-625.
PubMed Link
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Structure determination of the human protective protein: Twofold averaging reveals the three-dimensional structure of a domain which was entirely absent in the initial model.
Acta Crystallographica Section D - Biological Crystallography, 52, 923-936.
PubMed Link
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Three-dimensional structure of the human protective protein - Structure of the precursor form suggests a complex activation mechanism.
Structure, 3, 1249-1259.
PubMed Link
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N-glycosylation and deletion mutants of the human MDR1 p-glycoprotein.
Journal of Biological Chemistry, 268, 7474-7481.
PubMed Link
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In search of new lead compounds for trypanosomiasis drug design - A protein structure-based linked fragment approach.
Journal of Computer-Aided Molecular Design, 6 131-147.
PubMed Link
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Rudenko, G., & Deisenhofer, J. (2003).
The low-density lipoprotein receptor: Ligands, debates and lore.
Current Opinion in Structural Biology, 13, 683-689.
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