Publications

Recent Articles | Articles (1994-2004) | Review Articles | Editorial Material | Letters

Articles

Kiel M.J., S. He, R. Ashkenazi, S.N. Gentry, M. Teta, J.A. Kushner, T. L. Jackson and S.J. Morrison. 2007. Hematopoietic stem cells do not asymmetrically segregate chromosomes or retain bromodeoxyuridine. Nature (In press). PubMed Link

Kiel M.J., G.L. Radice and S.J. Morrison. 2007. Lack of evidence that hematopoietic stem cells depend on N-cadherin-mediated adhesion to osteoblasts for their maintenance. Cell Stem Cells 1: 204-217. Cell Stem Cells Summary

Kim, I., T.L. Saunders and S.J. Morrison. 2007. Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells. Cell 130: 470-483. PubMed Link

Kim, I., He, S. H., Yilmaz, O. H., Kiel, M. J., & Morrison, S. J. (2006). Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors. Blood, 108, 737-744. PubMed Link

Molofsky, A.V., Slutsky, S.G., Joseph, N.M., He, S., Pardal, R., Krishnamurthy, J., Sharpless, N., & Morrison, S.J. (2006). Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443, 448-452 PubMed Link

Yilmaz, O. H., Kiel, M. J., & Morrison, S. J. (2006). SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity. Blood, 107, 924-930. PubMed Link

Yilmaz, O. H., Valdez, R., Theisen, B. K., Guo, W., Ferguson, D. O., Wu, H., & Morrison, S. J. (2006). Pten dependence distinguishes hematopoietic stem cells from leukemia-initiating cells. Nature, 441, 475-482. PubMed Link

Morrison, S. J., & Kimble, J. (2006). Asymmetric and symmetric stem-cell divisions in development and cancer. Nature, 441, 1068-1074. Nature, 441, 1068-1074. PubMed Link

Kim, I., Yilmaz, O. H., & Morrison, S. J. (2005). CD144 (VE-cadherin) is transiently expressed by fetal liver hematopoietic stem cells. Blood, 106, 903-905. PubMed Link

Kiel, M. J., Yilmaz, O. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005). SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell, 121, 1109-1121. PubMed Link

Kiel, M. J., Iwashita, T., Yilmaz, O. H., & Morrison, S. J. (2005). Spatial differences in hematopoiesis but not in stem cells indicate a lack of regional patterning in definitive hematopoietic stem cells. Developmental Biology, 283, 29-39. PubMed

Molofsky, A. V., He, S. H., Bydon, M., Morrison, S. J., & Pardal, R. (2005). Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16(Ink4a) and P19(Arf) senescence pathways. Genes & Development, 19, 1432-1437. PubMed Link

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Articles (1994-2004)

Joseph, N. M., Mukouyama, Y. S., Mosher, J. T., Jaegle, M., Crone, S. A., Dormand, E. L., Lee, K. F., Meijer, D., Anderson, D. J., & Morrison, S. J. (2004). Neural crest stem cells undergo multilineage differentiation in developing peripheral nerves to generate endoneurial fibroblasts in addition to Schwann cells. Development, 131, 5599-5612. PubMed Link

Oravecz-Wilson, K. I., Kiel, M. J., Li, L., Rao, D. S., Saint-Dic, D., Kumar, P. D., Provot, M. M., Hankenson, K. D., Reddy, V. N., Lieberman, A. P., Morrison, S. J., & Ross, T. S. (2004). Huntingtin Interacting Protein 1 mutations lead to abnormal hematopoiesis, spinal defects, and cataracts. Human Molecular Genetics, 13, 851-867. PubMed Link

Park, I. K., Morrison, S. J., & Clarke, M. F. (2004). Bmi1, stem cells, and senescence regulation. Journal of Clinical Investigation, 113, 175-179. PubMed Link

Park, I. K., Qian, D. L., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., & Clarke, M. F. (2003). Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature, 423, 302-305. PubMed Link

Molofsky, A. V., Pardal, R., Iwashita, T., Park, I. K., Clarke, M. F., & Morrison, S. J. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature, 425, 962-967. PubMed Link

Alvarez-Dolado, M., Pardal, R., Garcia-Vardugo, J. M., Fike, J. R., Lee, H. O., Pfeffer, K., Lois, C., Morrison, S. J., & Alvarez-Buylla, A. (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature, 425, 968-973. PubMed Link

Kruger, G. M., Mosher, J. T., Tsai, T. H., Yeager, K. J., Iwashita, T., Gariepy, C. E., & Morrison, S. J. (2003). Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells. Neuron, 40, 917-929. PubMed Link

Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J., & Clarke, M. F. (2003). Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences of the USA, 100, 3983-3988. [Correction: 100, 6890.] PubMed Link

Iwashita, T., Kruger, G. M., Pardal, R., Kiel, M. J., & Morrison, S. J. (2003). Hirschsprung disease is linked to defects in neural crest stem cell function. Science, 301, 972-976. PubMed Link

Kubu, C. J., Orimoto, K., Morrison, S. J., Weinmaster, G., Anderson, D. J., & Verdi, J. M. (2002). Developmental changes in Notch1 and Numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells. Developmental Biology, 244, 199-214. PubMed Link

Morrison, S. J., Qian, D., Jerabek, L., Thiel, B. A., Park, I. K., Ford, P. S., Kiel, M. J., Schork, N. J., Weissman, I. L., & Clarke, M. F. (2002). A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. Journal of Immunology, 168, 635-642. PubMed Link

Bixby, S., Kruger, G. M., Mosher, J. T., Joseph, N. M., & Morrison, S. J. (2002). Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity. Neuron, 35, 643-656. PubMed Link

Kruger, G. M., Mosher, J. T., Bixby, S., Joseph, N., Iwashita, T., & Morrison, S. J. (2002). Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness. Neuron, 35, 657-669. PubMed Link

Morrison, S. J. (2001). Stem cell potential: Can anything make anything? Current Biology, 11, R7-R9. PubMed Link

Morrison, S. J. (2001). Neuronal differentiation: Proneural genes inhibit gliogenesis. Current Biology, 11, R349-R351. PubMed Link

Morrison, S. J. (2001). Neuronal potential and lineage determination by neural stem cells. Current Opinion in Cell Biology, 13, 666-672. PubMed Link

White, P. M., Morrison, S. J., Orimoto, K., Kubu, C. J., Verdi, J. M., & Anderson, D. J. (2001). Neural crest stem cells undergo cell-intrinsic developmental changes in sensitivity to instructive differentiation signals. Neuron, 29, 57-71. PubMed Link

Morrison, S. J., Perez, S. E., Qiao, Z., Verdi, J. M., Hicks, C., Weinmaster, G., & Anderson, D. J. (2000). Transient notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell, 101, 499-510. PubMed Link

Morrison, S. J., Csete, M., Groves, A. K., Melega, W., Wold, B., & Anderson, D. J. (2000). Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells. Journal of Neuroscience, 20, 7370-7376. PubMed Link

Morrison, S. J., White, P. M., Zock, C., & Anderson, D. J. (1999). Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells. Cell, 96, 737-749. PubMed Link

Cheshier, S. P., Morrison, S. J., Liao, X. S., & Weissman, I. L. (1999). In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proceedings of the National Academy of Sciences of the USA, 96, 3120-3125. PubMed Link

Klug, C. A., Morrison, S. J., Masek, M., Hahm, K., Smale, S. T., & Weissman, I. L. (1998). Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes. Proceedings of the National Academy of Sciences of the USA, 95, 657-662. PubMed Link

Morrison, S. J., Wandycz, A. M., Hemmati, H. D., Wright, D. E., & Weissman, I. L. (1997). Identification of a lineage of multipotent hematopoietic progenitors. Development, 124, 1929-1939. PubMed Link

Morrison, S. J., Wright, D. E., & Weissman, I. L. (1997). Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proceedings of the National Academy of Sciences of the USA, 94, 1908-1913. PubMed Link

Morrison, S. J., Prowse, K. R., Ho, P., & Weissman, I. L. (1996). Telomerase activity in hematopoietic cells is associated with self-renewal potential. Immunity, 5, 207-216. PubMed Link

Morrison, S. J., Wandycz, A. M., Akashi, K., Globerson, A., & Weissman, I. L. (1996). The aging of hematopoietic stem cells. Nature Medicine, 2, 1011-1016. PubMed Link

Morrison, S. J., & Weissman, I. L. (1995). Heterogeneity of hematopoietic stem cells - Implications for clinical applications. Proceedings of the Association of American Physicians, 107, 187-194. PubMed Link

Morrison, S. J., Hemmati, H. D., Wandycz, A. M., & Weissman, I. L. (1995). The purification and characterization of fetal liver hematopoietic stem cells. Proceedings of the National Academy of Sciences of the USA, 92, 10302-10306. PubMed Link

Morrison, S. J., & Weissman, I. L. (1994). The long-term repopulating subset of hematopoietic stem cells is deterministic and isolatable by phenotype. Immunity, 1, 661-673. PubMed Link

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Review Articles

Joseph, N. M., & Morrison, S. J. (2005). Toward an understanding of the physiological function of mammalian stem cells. Developmental Cell, 9, 173-183. PubMed Link

Molofsky, A. V., Pardal, R., & Morrison, S. J. (2004). Diverse mechanisms regulate stem cell self-renewal. Current Opinion in Cell Biology, 16, 700-707.

Pardal, R., Clarke, M. F., & Morrison, S. J. (2003). Applying the principles of stem-cell biology to cancer. Nature Reviews Cancer, 3, 895-902. PubMed Link

Kruger, G. M., & Morrison, S. J. (2002). Brain repair by endogenous progenitors. Cell, 110, 399-402. PubMed Link

Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001). Stem cells, cancer, and cancer stem cells. Nature, 414, 105-111. PubMed Link

Morrison, S. J., Shah, N. M., & Anderson, D. J. (1997). Regulatory mechanisms in stem cell biology. Cell, 88, 287-298.

Morrison, S. J., Wright, D. E., Cheshier, S. H., & Weissman, I. L. (1997). Hematopoietic stem cells: Challenges to expectations. Current Opinion in Immunology, 9, 216-221.

Aguila, H. L., Akashi, K., Domen, J., Gandy, K. L., Lagasse, E., Mebius, R. E., Morrison, S. J., Shizuru, J., Strober, S., Uchida, N., Wright, D. E., & Weissman, I. L. (1997). From stem cells to lymphocytes: Biology and transplantation. Immunological Reviews, 157, 13-40.

Morrison, S. J., Uchida, N., & Weissman, I. L. (1995). The biology of hematopoietic stem cells. Annual Review of Cell and Developmental Biology, 11, 35-71.

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Editorial Material

Mosher, J. T., & Morrison, S. J. (2004). Crossing the boundaries of sensory neurogenesis. Nature Neuroscience, 7, 900-902.

Orkin, S. H., & Morrison, S. J. (2002). Stem-cell competition. Nature, 418, 25-27.

Morrison, S. J. (2002). Pten-uating neural growth. Nature Medicine, 8, 16-18.

Morrison, S. J. (2000). The last shall not be first: The ordered generation of progeny from stem cells. Neuron, 28, 1-3.

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Letters

Morrison, S. J., & Weissman, I. L. (1996). More or less hematopoietic stem cells - Reply. Nature Medicine, 2, 1282-1283.

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