Selected Publications

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Kiel, M., He, S., Ashkenazi, R., Gentry, S.N., Teta, M., Kushner, J.A., Jackson, T.L., & Morrison, S.J. (2007). Hematopoietic stem cells do not asymmetrically segregate chromosomes or retain bromodeoxyuridine. Nature 449, 238-242 PubMed Link

Kim, I., Saunders, T.L., Morrison, S.J. Sox17 Dependence Distinguishes the Transcriptional Regulation of Fetal from Adult Hematopoietic Stem Cells. Cell (in press) PubMed Link

Molofsky, A.V., Slutsky, S.G., Joseph, N.M., He, S., Pardal, R., Krishnamurthy, J., Sharpless, N., & Morrison, S.J. (2006). Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443, 448-452 PubMed Link

Yilmaz, O. H., Valdez, R., Theisen, B. K., Guo, W., Ferguson, D. O., Wu, H., & Morrison, S. J. (2006). Pten dependence distinguishes hematopoietic stem cells from leukemia-initiating cells. Nature, 441, 475-482. PubMed Link

Morrison, S. J., & Kimble, J. (2006). Asymmetric and symmetric stem-cell divisions in development and cancer. Nature, 441, 1068-1074. PubMed Link

Joseph, N. M., & Morrison, S. J. (2005). Toward an understanding of the physiological function of mammalian stem cells. Developmental Cell, 9, 173-183. PubMed Link

Kiel, M. J., Yilmaz, O. H., Iwashita, T., Yilmaz, O. H., Terhorst, C., & Morrison, S. J. (2005). SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell, 121, 1109-1121. PubMed Link

Molofsky, A. V., He, S. H., Bydon, M., Morrison, S. J., & Pardal, R. (2005). Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16(Ink4a) and P19(Arf) senescence pathways. Genes & Development, 19, 1432-1437. PubMed Link

Pardal, R., Clarke, M. F., & Morrison, S. J. (2003). Applying the principles of stem-cell biology to cancer. Nature Reviews Cancer, 3, 895-902. PubMed Link

Molofsky, A. V., Pardal, R., Iwashita, T., Park, I. K., Clarke, M. F., & Morrison, S. J. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature, 425, 962-967. PubMed Link

Alvarez-Dolado, M., Pardal, R., Garcia-Vardugo, J. M., Fike, J. R., Lee, H. O., Pfeffer, K., Lois, C., Morrison, S. J., & Alvarez-Buylla, A. (2003). Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature, 425, 968-973. PubMed Link

Iwashita, T., Kruger, G. M., Pardal, R., Kiel, M. J., & Morrison, S. J. (2003). Hirschsprung disease is linked to defects in neural crest stem cell function. Science, 301, 972-976. PubMed Link

Park, I. K., Qian, D. L., Kiel, M., Becker, M. W., Pihalja, M., Weissman, I. L., Morrison, S. J., & Clarke, M. F. (2003). Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature, 423, 302-305. PubMed Link

Al-Hajj, M., Wicha, M. S., Benito-Hernandez, A., Morrison, S. J., & Clarke, M. F. (2003). Prospective identification of tumorigenic breast cancer cells. Proceedings of the National Academy of Sciences of the USA, 100, 3983-3988. [Correction: 100, 6890.] PubMed Link

Kruger, G. M., & Morrison, S. J. (2002). Brain repair by endogenous progenitors. Cell, 110, 399-402. PubMed Link

Bixby, S., Kruger, G. M., Mosher, J. T., Joseph, N. M., & Morrison, S. J. (2002). Cell-intrinsic differences between stem cells from different regions of the peripheral nervous system regulate the generation of neural diversity. Neuron, 35, 643-656. PubMed Link

Kruger, G. M., Mosher, J. T., Bixby, S., Joseph, N., Iwashita, T., & Morrison, S. J. (2002). Neural crest stem cells persist in the adult gut but undergo changes in self-renewal, neuronal subtype potential, and factor responsiveness. Neuron, 35, 657-669. PubMed Link

Reya, T., Morrison, S. J., Clarke, M. F., & Weissman, I. L. (2001). Stem cells, cancer, and cancer stem cells. Nature, 414, 105-111. PubMed Link

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