Publications
Recent Articles | Articles (2000-2004) | Articles (1996-1999)
Recent Articles
Maillard I., U. Koch, A. Dumortier, O. Shestova, L. Xu, H. Sai, S.E. Pross, J.C. Aster, A. Bhandoola, F. Radtke and W.S. Pear. Canonical Notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. Cell Stem Cell, 2(4), 356-366, 2008. PubMed Link
Guo Y., I. Maillard, S. Chakraborti, E.V. Rothenberg and N.S. Speck. Core binding factors are necessary for natural killer cell development, and cooperate with Notch signaling during T cell specification. Blood, epub ahead of print, 2008. PubMed Link
Santos M.A., L.M. Sarmento, M. Rebelo, A.A. Doce, I. Maillard, A. Dumortier, H. Neves, F. Radtke, W.S. Pear, L. Parreira and J. Demengeot. Notch1 engagement by Delta-like-1 promotes differentiation of B lymphocytes to antibody-secreting cells. Proc. Natl. Acad. Sci. USA, 104(39):15454-15459, 2007. PubMed Link
Wu L.*, I. Maillard*, M. Nakamura, W.S. Pear and J.D. Griffin. The transcriptional co-activator Maml1 is required for Notch2-mediated marginal zone B cell development. Blood, 110(10):3618-23, 2007 (*equal contribution). PubMed Link
I. Maillard and W.S. Pear. Keeping a tight leash on Notch. Science, 316:840-842, 2007. Science Summary
Zediak V.P., I. Maillard, and A. Bhandoola. Multiple pre-thymic defects underlie age-related loss of T progenitor competence. Blood, 110:1161-7, 2007. PubMed Link
Schwarz B.A., A. Sambandam, I. Maillard, B.C. Harman, P.E. Love and A. Bhandoola. Selective thymus settling regulated by cytokine and chemokine receptors. J. Immunol., 178:2008-17, 2007. PubMed Link
Thomas M., M. Calamito, B. Srivastava, I. Maillard, W.S. Pear and D. Allman. Notch activity synergizes with B cell receptor and CD40 signaling to enhance B cell activation. Blood, 109:3342-50, 2006. PubMed Link
K. Keeshan, Y. He, B.J. Wouters, O. Shestova, H. Sai, C.G. Rodriguez, I. Maillard, J.W. Tobias, P. Valk, M. Carroll, J.C. Aster, R. Delwel and W.S. Pear. Tribbles homolog 2 (Trib2) inactivates C/EBP alpha and causes acute myelogenous leukemia. Cancer Cell, 10(5): 401-11, 2006. Pubmed Link
L. Talebian, Z. Li, Y. Guo, J. Gaudet, M.E. Speck, D. Sugiyama, P. Kaur, W.S. Pear, I. Maillard* and N.A. Speck*. T lymphoid, megacaryocyte, and granulocyte development are sensitive to decreases in CBFbeta dosage. Blood, 1;109(1): 11-21, 2006 (*corresponding authors). PubMed Link
Maillard I., L. Tu, A. Sambandam, Y. Yashiro-Ohtani, J. Millholland, K. Keeshan, O. Shestova, L. Xu, A. Bhandoola and W.S. Pear. The requirement for Notch signaling at the beta selection checkpoint in vivo is absolute and independent of the pre-T cell receptor. J. Exp. Med., 203(10): 2239-45, 2006. PubMed Link
Maillard I., B. Schwarz, A. Sambandam, T. Fang, O. Shestova, L. Xu, A. Bhandoola and W.S. Pear. Notch-dependent T lineage commitment occurs at extrathymic sites following bone marrow transplantation. Blood, 107(9): 3511-19, 2006. PubMed Link
Tu L., T.C. Fang, D. Artis, O. Shestova, S.E. Pross, I. Maillard and W.S. Pear. Notch signaling is an important regulator of type 2 immunity. J. Exp. Med., 202(8):1037-42, 2005. PubMed Link
Zediak V.P., I. Maillard and A. Bhandoola. Closer to the source: Notch and the nature of thymus settling cells. Immunity, 23(3): 245-48, 2005. PubMed Link
Sambandam A.*, I. Maillard*, V.P. Zediak, L. Xu, R.M. Gerstein, J.C. Aster, W.S. Pear and A. Bhandoola. Notch signaling controls the generation and differentiation of early T lineage progenitors. Nature Immunology, 6(7):663-70, 2005 (*equal contribution). PubMed Link
Maillard I., T. Fang and W.S. Pear. Regulation of lymphoid development, differentiation and function by the Notch pathway. Annu Rev Immunol, 23:945-974, 2005. PubMed Link
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Articles (2000-2004)
Kumar R., I. Maillard, S.J. Schuster and A. Alavi. Utility of fluorodeoxyglucose-PET imaging in the management of patients with Hodgkin's and non-Hodgkin's lymphomas. Radiol Clin North Am, 42(6):1083-100, 2004. PubMed Link
Maillard I., A.P. Weng, A.C. Carpenter, C.G. Rodriguez, H. Sai, L. Xu, D. Allman, J.C. Aster, and W.S. Pear. Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood, 104(6):1696-702, 2004. PubMed Link
Maillard I., S.H. Adler and W.S. Pear. Notch and the immune system. Immunity, 19(6): 781-91, 2003. PubMed Link
D.E. Tsai, I. Maillard, L. Downs, A. Alavi, S.D. Nasta, E.A. Stadtmauer, D.L. Porter, T.R. Klumpp, S.M. Luger and S.J. Schuster. Use of Iodine 131I Tositumomab Radioimmunotherapy in a Patient with Waldenstrom's Macroglobulinemia. Leuk Lymphoma, 45(3): 591-595, 2004. PubMed Link
Tsai D.E., I. Maillard, S.J. Schuster, S.D. Nasta, D.L. Porter, T.R. Klumpp, D.M. Goldenberg, S.M. Luger, A. Alavi, R.M. Sharkey, K.B. Hartzell and E.A. Stadtmauer. Use of ibritumomab tiuxetan anti-CD20 radioimmunotherapy in a non-Hodgkin's lymphoma patient previously treated with a yttrium-90-labeled anti-CD22 monoclonal antibody. Clin Lymphoma 4(1): 56-9, 2003. PubMed Link
Maillard I., Y. He and W.S. Pear. From the yolk sac to the spleen: new roles for Notch in regulating hematopoiesis. Immunity 18(5): 587-589, 2003. PubMed Link
Maillard I. and W.S. Pear. Notch and cancer: Best to avoid the ups and downs. Cancer Cell 3(3):203-5, 2003. PubMed Link
Allenspach E.J., I. Maillard, J.C. Aster and W.S. Pear. Notch signaling in cancer. Cancer Biol. Ther. 1(5):466-76, 2002. PubMed Link
Stupp R., P.Y. Dietrich, S. Ostermann Kraljevic, A. Pica, I. Maillard, P. Maeder, R. Meuli, R. Janzer, G. Pizzolatto, R. Miralbell, F. Porchet, L. Regli, N. de Tribolet, R.O. Mirimanoff and S. Leyvraz. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J. Clin. Oncol. 20(5):1375-1382, 2002. PubMed Link
Baribaud F., S. Wirth, I. Maillard, S. Valsesia, H. Acha-Orbea and H. Diggelmann. Identification of key amino acids of the mouse mammary tumor virus superantigen involved in the specific interaction with T-cell receptor V beta domains. J. Virol. 75(16):7453-6, 2001. PubMed Link
Maillard I., P. Launois, H. Himmelrich, H. Acha-Orbea, H. Diggelmann, R.M. Locksley and J.A. Louis. Functional plasticity of the LACK-reactive Vbeta4-Valpha8 CD4+ T cells normally producing the early IL-4 instructing Th2 cell development and susceptibility to Leishmania major infection in BALB/c mice. Eur. J. Immunol. 31(4):1288-96, 2001. PubMed Link
Maillard I., V. Schweizer, A. Broccard, A. Duscher, L. Liaudet and M.D. Schaller. Use of botulinum toxin type A to avoid tracheal intubation or tracheostomy in severe paradoxical vocal cord movement. Chest 118(3), 874-7, 2000. PubMed Link
Nishino I., A. Spinazzola, A. Papadimitriou, S. Hammans, I. Steiner, C.D. Hahn, A.M. Connolly, A. Verloes, J. Guimaraes, I. Maillard et al. Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations. Ann. Neurol. 47(6), 792-800, 2000. PubMed Link
Himmelrich H., P. Launois, I. Maillard, T. Biedermann, F. Tacchini-Cottier, R.M. Locksley, M. Rocken and J.A. Louis. In BALB/c mice, IL-4 production during the initial phase of infection with Leishmania major is necessary and sufficient to instruct Th2 cell development resulting in progressive disease. J. Immunol. 164(9), 4819-25, 2000. PubMed Link
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Articles (1996-1999)
Baribaud F., I. Maillard, S. Vacheron, T. Brocker, H. Diggelmann and H. Acha-Orbea. Role of dendritic cells in the immune response induced by mouse mammary tumor virus superantigen. J. Virol. 73(10): 8403-10, 1999. PubMed Link
Maillard I., I. Xenarios, H. Diggelmann, and H. Acha-Orbea. Differential reactivity of TCR Vbeta10 alleles to a mouse mammary tumor virus superantigen. Eur. J. Immunol. 28: 3075-3085, 1998. PubMed Link
Maillard I., F. Luthi, H. Acha-Orbea and H. Diggelmann. Role of the immune response induced by superantigens in the pathogenesis of microbial infections. Parasitology 115: S67-S78, 1997. PubMed Link
Maillard I., P. Launois, I. Xenarios, J. A. Louis, H. Acha-Orbea, and H. Diggelmann. Immune response to mouse mammary tumor virus in mice lacking the alpha/beta interferon or the gamma interferon receptor. J. Virol. 72: 2638-2646, 1998. PubMed Link
P. Launois, I. Maillard, S. Pingel, K.G. Swihart, I. Xenarios, H. Acha-Orbea, H. Diggelmann, R.M. Locksley, H.R. MacDonald, and J.A. Louis. IL-4 rapidly produced by Vbeta4 Valpha8 CD4+ T cells instructs Th2 development and susceptibility to Leishmania major in BALB/c mice. Immunity 6: 541-549, 1997. PubMed Link
Luther, S. A., I. Maillard, F. Luthi, L. Scarpellino, H. Diggelmann, and H. Acha-Orbea. Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells. J. Immunol. 159: 2807-2814, 1997. PubMed Link
Maillard I., K. Erny, H. Acha-Orbea, and H. Diggelmann. A Vbeta4-specific superantigen encoded by a new exogenous mouse mammary tumor virus. Eur. J. Immunol. 26: 1000-1006, 1996. PubMed Link
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