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Publications

Recent Articles | Articles (1998-2004) | Articles (1989-1997) | Articles (1982-1988) | Review Articles | Editorial Material | Letters | Notes

Recent Articles
Autophagy

Yorimitsu, T., Zaman, S., Broach, J.R., & Klionsky, D.J.. 2007. Protein kinase A and Sch9 cooperatively regulate induction of autophagy in Saccharomyces cerevisiae. Mol. Bio. Cell, in press.

Huang, J., Reggiori, F., & Klionsky, D.J. 2007. The transmembrane domain of acid trehalase mediates ubiquitin-independent Multivesicular body pathway sorting. Mol. Biol. Cell, in press.

Yorimitsu, T., & Klionsky, D.J. (2007). Eating the endoplasmic reticulum: quality control by autophagy. Trends Cell Biol. 17, 279-85. PubMed Link

Klionsky, D.J., Cuervo, A.M., & Seglen, P.O. (2007). Methods for monitoring autophagy from yeast to human. Autophagy 3, 181-206. PubMed Link

Rubinsztein, D.C., Gestwicki, J.E., Murphy, L.O., and Klionsky, D.J. (2007). Potential therapeutic applications of autophagy. Nat Rev Drug Discov 6, 304-12. PubMed Link

Cao, Y., & Klionsky, D.J. (2007). Atg26 is not involved in autophagy-related pathways in Saccharomyces cerevisiae. Autophagy 3, 17-20. PubMed Link

Yen, W.-L., Legakis, J.E., Nair, U., & Klionsky, D.J. (2007). Atg27 is required for autophagy-dependent cycling of Atg9. Molecular Biology of the Cell 18, 581-593. PubMed Link

He, C., Song, H., Yorimitsu, T., Monastyrska, I., Yen, W.-L., Legakis, J.E., & Klionsky, D.J. (2006). Recruitment of Atg9 to the pre-autophagosomal structure by Atg11 is essential for selective autophagy in budding yeast. Journal of Cell Biology 175, 925-935. [Cover illustration] PubMed Link

Yang, Z., Huang, J., Geng, J., Nair, U., & Klionsky, D.J. (2006). Atg22 recycles amino acids to link the degradative and recycling functions of autophagy. Molecular Biology of the Cell 17, 5094-5104. PubMed Link

Yorimitsu, T., Nair, U., Yang, Z., & Klionsky, D.J. (2006). Endoplasmic reticulum stress triggers autophagy. Journal of Biological Chemistry 281, 30299-30304. PubMed Link

Monastyrska, I., & Klionsky, D.J. (2006). Autophagy in organelle homeostasis: Peroxisome turnover. Molecular Aspects of Medicine 27, 483-494. PubMed Link

Reggiori, F., & Klionsky, D.J. (2006). Atg9 sorting from mitochondria is impaired in early secretion and VFT complex mutants in Saccharomyces cerevisiae. Journal of Cell Science 119, 2903-2911. PubMed Link

Legakis, J.E., & Klionsky, D.J. (2006). Overview of autophagy. In Autophagy in Immunity and Infection. A Novel Immune Effector (Deretic, V. ed). Wiley-VCH, Weinheim, pp. 3-17.

Klionsky, D.J. (2006). Good riddance to bad rubbish. Nature 441, 819-820. PubMed Link

He, C., & Klionsky, D.J. (2006). Autophagy and neurodegeneration. ACS Chemical Biology 1, 211-213. PubMed Link

Monastyrska, I., Shintani, T., Klionsky, D. J., & Reggiori, F. (2006). Atg11 directs autophagosome cargoes to the PAS along actin cables. Autophagy, 2, 119-121. PubMed Link

Reggiori, F., & Klionsky, D. J. (2006). Atg9 sorting from mitochondria is impaired in early secretion and VFT-complex mutants in Saccharomyces cerevisiae. Journal of Cell Science, 119, 2903-2911. PubMed Link

Nazarko, T. Y., Huang, J., Nicaud, J. M., Klionsky, D. J., & Sibirny, A. A. (2005). Trs85 is required for macroautophagy, pexophagy and cytoplasm to vacuole targeting in Yarrowia apolytica and Saccharomyces rereviesioue. Autophagy, 1, 37-45. PubMed Link

Reggiori, F., Shintani, T., Nair, U., & Klionsky, D. J. (2005). Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy, 1, 101-109. PubMed Link

Towns, R., Kabeya, Y., Yoshimori, T., Guo, C. F., Shangguan, Y., Hong, S., Kaplan, M., Klionsky, D. J., & Wiley, J. W. (2005). Sera from patients with type 2 diabetes and neuropathy induce autophagy and colocalization with mitochondria in SY5Y cells. Autophagy, 1, 163-170. PubMed Link

Reggiori, F., & Klionsky, D. J. (2005). Autophagosomes: Biogenesis from scratch? Current Opinion in Cell Biology, 17, 415-422. PubMed Link

Yorimitsu, T., & Klionsky, D. J. (2005). Atg11 links cargo to the vesicle forming machinery in the cytoplasm to vacuole targeting pathway. Molecular Biology of the Cell, 16, 1593-1605. PubMed Link

Cheong, H., Yorimitsu, T., Reggiori, F., Legakis, J. E., Wang, C. W., & Klionsky, D. J. (2005). Atg17 regulates the magnitude of the autophagic response. Molecular Biology of the Cell, 16, 3438-3453. PubMed Link

Reggiori, F., Monastyrska, L., Shintani, T., & Klionsky, D. J. (2005). The actin cytoskeleton is required for selective types of autophagy, but not nonspecific autophagy, in the yeast Saccharomyces cerevisiae. Molecular Biology of the Cell, 16, 5843-5856. PubMed Link

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Recent Articles Teaching/Learning

Klionsky, D.J. (2006). Why don’t we teach the telephone book? The Teaching Professor 20, 7.

Klionsky, D.J., & Kumar, A. (2006). A systems biology approach to learning autophagy. Autophagy 2, 12-23.

Klionsky, D.J. (2007). Malpractice insurance for university professors? The Teaching Professor 21, 6.

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Articles (1998-2004)

Reggiori, F., Tucker, K. A., Stromhaug, P. E., & Klionsky, D. J. (2004). The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Developmental Cell, 6, 79-90. PubMed Link

Budovskaya, Y. V., Stephan, J. S., Reggiori, F., Klionsky, D. J., & Herman, P. K. (2004). The Ras/cAMP-dependent protein kinase signaling pathway regulates an early step of the autophagy process in Saccharomyces cerevisiae. Journal of Biological Chemistry, 279, 20663-20671. PubMed Link

Shintani, T., & Klionsky, D. J. (2004). Cargo proteins facilitate the formation of transport vesicles in the cytoplasm-to-vacuole targeting pathway. Journal of Biological Chemistry, 279, 29889-29894. PubMed Link

Stromhaug, P. E., Reggiori, F., Guan, J., Wang, C. W., Klionsky, D. J. (2004). Atg21 is a phosphoinositide binding protein required for efficient lipidation and localization of Atg8 during uptake of aminopeptidase I by selective autophagy. Molecular Biology of the Cell, 15, 3553-3566. PubMed Link

Reggiori, F., Wang, C. W., Stromhaug, P. E., Shintani, T., & Klionsky, D. J. (2003). Vps51 is part of the yeast Vps53 tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion. Journal of Biological Chemistry, 278, 5009-5020. PubMed Link

Tucker, K. A., Reggiori, F., Dunn, W. A., & Klionsky, D. J. (2003). Atg23 is essential for the cytoplasm-to-vacuole targeting pathway and efficient autophagy but not pexophagy. Journal of Biological Chemistry, 278, 48445-48452. PubMed Link

Wang, C. W., Stromhaug, P. E., Kauffmann, E. J., Weisman, L. S., & Klionsky, D. J. (2003). Yeast homotypic vacuole fusion requires the Ccz1-Mon1 complex during the tethering/docking stage. Journal of Cell Biology, 163, 973-985. PubMed Link

Abeliovich, H., Zhang, C., Dunn, W. A., Shokat, K. M., & Klionsky, D. J. (2003). Chemical genetic analysis of Apg1 reveals a nonkinase role in the induction of autophagy. Molecular Biology of the Cell, 14, 477-490. PubMed Link

Wang, C. W., & Klionsky, D. J. (2003). The molecular mechanism of autophagy. Molecular Medicine, 9, 65-76. PubMed Link

Shintani, T., Huang, W. P., Stromhaug, P. E., & Klionsky, D. J. (2002). Mechanism of cargo selection in the cytoplasm-to-vacuole targeting pathway. Developmental Cell, 3, 825-837. PubMed Link

Kim, J., Huang, W. P., Stromhaug, P. E., & Klionsky, D. J. (2002). Convergence of multiple autophagy and cytoplasm-to-vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation. Journal of Biological Chemistry, 277, 763-773. PubMed Link

Nice, D. C., Sato, T. K., Stromhaug, P. E., Emr, S. D., & Klionsky, D. J. (2002). Cooperative binding of the cytoplasm-to-vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy. Journal of Biological Chemistry, 277, 30198-30207. PubMed Link

Wang, C. W., Stromhaug, P. E., Shima, J., & Klionsky, D. J. (2002). The Ccz1-Mon1 protein complex is required for the late step of multiple vacuole delivery pathways. Journal of Biological Chemistry, 277, 47917-47927. PubMed Link

Teter, S. A., Eggerton, K. P., Scott, S. V., Kim, J., Fischer, A. M., Klionsky, D. J. (2001). Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase. Journal of Biological Chemistry, 276, 2083-2087. PubMed Link

Hutchins, M. U., & Klionsky, D. J. (2001). Vacuolar localization of oligomeric alpha-mannosidase requires the cytoplasm-to-vacuole targeting and autophagy pathway components in Saccharomyces cerevisiae. Journal of Biological Chemistry, 276, 20491-20498. PubMed Link

Wang, C. W., Kim, J., Huang, W. P., Abeliovich, H., Stromhaug, P. E., Dunn, W. A., & Klionsky, D. J. (2001). Apg2 is a novel protein required for the cytoplasm-to-vacuole targeting, autophagy, and pexophagy pathways. Journal of Biological Chemistry, 276, 30442-30451. PubMed Link

Kim, J., Huang, W. P., & Klionsky, D. J. (2001). Membrane recruitment of Aut7p in the autophagy and cytoplasm-to-vacuole targeting pathways requires Aut1p, Aut2p, and the autophagy conjugation complex. Journal of Cell Biology, 152, 51-64. PubMed Link

Kim, J., Kamada, Y., Stromhaug, P. E., Guan, J., Hefner-Gravink, A., Baba, M., Scott, S. V., Ohsumi, Y., Dunn, W. A., & Klionsky, D. J. (2001). Cvt9/Gsa9 functions in sequestering selective cytosolic cargo destined for the vacuole. Journal of Cell Biology, 153, 381-396. PubMed Link

Guan, J., Stromhaug, P. E., George, M. D., Habibzadegah-Tari, P., Bevan, A., Dunn, W. A., & Klionsky, D. J. (2001). Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris. Molecular Biology of the Cell, 12, 3821-3838. PubMed Link

Scott, S. V., Guan, J., Hutchins, M. U., Kim, J., & Klionsky, D. J. (2001). Cvt19 is a receptor for the cytoplasm-to-vacuole targeting pathway. Molecular Cell, 7, 1131-1141. PubMed Link

Huang, W. P., Scott, S. V., Kim J., & Klionsky, D. J. (2000). The itinerary of a vesicle component, Aut7p/Cvt5p, terminates in the yeast vacuole via the autophagy/Cvt pathways. Journal of Biological Chemistry, 275, 5845-5851. PubMed Link

Scott, S. V., Nice, D. C., Nau, J. J., Weisman, L. S., Kamada, Y., Keizer-Gunnink, I., Funakoshi, T., Veenhuis, M., Ohsumi, Y., & Klionsky, D. J. (2000). Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm-to-vacuole targeting. Journal of Biological Chemistry, 275, 25840-25849. PubMed Link

Noda, T., Kim, J., Huang, W. P., Baba, M., Tokunaga, C., Ohsumi, Y., & Klionsky, D. J. (2000). Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways. Journal of Cell Biology, 148, 465-479. PubMed Link

Abeliovich, H., Dunn, W. A., Kim, J., & Klionsky, D. J. (2000). Dissection of autophagosome biogenesis into distinct nucleation and expansion steps. Journal of Cell Biology, 151, 1025-1033. PubMed Link

George, M. D., Baba, M., Scott, S. V., Mizushima, N., Garrison, B. S., Ohsumi, Y., & Klionsky, D. J. (2000). Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways. Molecular Biology of the Cell, 11, 969-982. PubMed Link

Klionsky, D. J., & Tomashek, J. J. (1999). An interactive exercise to learn eukaryotic cell structure & organelle function. American Biology Teacher, 61, 539-542.

Hutchins, M. U., Veenhuis, M., & Klionsky, D. J. (1999). Peroxisome degradation in Saccharomyces cerevisiae is dependent on machinery of macroautophagy and the Cvt pathway. Journal of Cell Science, 112, 4079-4087. PubMed Link

Kim, J., Dalton, V. M., Eggerton, K. P., Scott, S. V., & Klionsky, D. J. (1999). Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways. Molecular Biology of the Cell, 10, 1337-1351. [Correction: 10, U5-U6.] PubMed Link

Teter, S. A., & Klionsky, D. J. (1999). How to get a folded protein across a membrane. Trends in Cell Biology, 9, 428-431. PubMed Link

Scott, S. V., & Klionsky, D. J. (1998). Delivery of proteins and organelles to the vacuole from the cytoplasm. Current Opinion in Cell Biology, 10, 523-529. PubMed Link

Fleckenstein, D., Rohde, M., Klionsky, D. J., & Rudiger, M. (1998). Yel013p (Vac8p), an armadillo repeat protein related to plakoglobin and importin alpha, is associated with the yeast vacuole membrane. Journal of Cell Science, 111, 3109-3118. PubMed Link

Mizushima, N., Noda, T., Yoshimori, T., Tanaka, Y., Ishii, T., George, M. D., Klionsky, D. J., Ohsumi, M., & Ohsumi, Y. (1998). A protein conjugation system essential for autophagy. Nature, 395, 395-398. PubMed Link

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Articles (1989-1997)

Tomashek, J. J., Garrison, B. S., & Klionsky, D. J. (1997). Reconstitution in vitro of the V-1 complex from the yeast vacuolar proton-translocating ATPase - Assembly recapitulates mechanism. Journal of Biological Chemistry, 272, 16618-16623. PubMed Link

Tomashek, J. J., Graham, L. A., Hutchins, M. U., Stevens, T. H., & Klionsky, D. J. (1997). V-1-situated stalk subunits of the yeast vacuolar proton-translocating ATPase. Journal of Biological Chemistry, 272, 26787-26793. PubMed Link

Kim, J., Scott, S. V., Oda, M. N., & Klionsky, D. J. (1997). Transport of a large oligomeric protein by the cytoplasm-to-vacuole protein targeting pathway. Journal of Cell Biology, 137, 609-618. PubMed Link

Scott, S. V., Baba, M., Ohsumi, Y., & Klionsky, D. J. (1997). Aminopeptidase I is targeted to the vacuole by a nonclassical vesicular mechanism. Journal of Cell Biology, 138, 37-44. PubMed Link

Baba, M., Osumi, M., Scott, S. V., Klionsky, D. J., & Ohsumi, Y. (1997). Two distinct pathways for targeting proteins from the cytoplasm to the vacuole/lysosome. Journal of Cell Biology, 139, 1687-1695. PubMed Link

Matoba, S., Morano, K. A., Klionsky, D. J., Kim, K., & Ogrydziak, D. M. (1997). Dipeptidyl aminopeptidase processing and biosynthesis of alkaline extracellular protease from Yarrowia lipolytica. Microbiology (UK), 143, 3263-3272. PubMed Link

Scott, S. V., & Klionsky, D. J. (1997). Nonclassical protein sorting. Trends in Cell Biology, 7, 225-229. PubMed Link

Kim, J., Alizadeh, P., Harding, T., Hefner-Gravink, A., & Klionsky, D. J. (1996). Disruption of the yeast ATH1 gene confers better survival after dehydration, freezing, and ethanol shock: Potential commercial applications. Applied and Environmental Microbiology, 62, 1563-1569. PubMed Link

Nelson, N., & Klionsky, D. J. (1996). Vacuolar H+-ATPase: From mammals to yeast and back. Experientia, 52, 1101-1110. PubMed Link

Alizadeh, P., & Klionsky, D. J. (1996). Purification and biochemical characterization of the ATH1 gene product, vacuolar acid trehalase, from Saccharomyces cerevisiae. FEBS Letters, 391, 273-278. PubMed Link

Tomashek, J. J., Sonnenburg, J. L., Artimovich, J. M., & Klionsky, D. J. (1996). Resolution of subunit interactions and cytoplasmic subcomplexes of the yeast vacuolar proton-translocating ATPase. Journal of Biological Chemistry, 271, 10397-10404. PubMed Link

Harding, T. M., Hefner-Gravink, A., Thumm, M., & Klionsky, D. J. (1996). Genetic and phenotypic overlap between autophagy and the cytoplasm-to-vacuole protein targeting pathway. Journal of Biological Chemistry, 271, 17621-17624. PubMed Link

Oda, M. N., Scott, S. V., Hefner-Gravink, A., Caffarelli, A. D., & Klionsky, D. J. (1996). Identification of a cytoplasm-to-vacuole targeting determinant in aminopeptidase I. Journal of Cell Biology, 132, 999-1010. PubMed Link

Wang, Y. X., Zhao, H. R., Harding, T. M., deMesquita, D. S. G., Woldringh, C. L., Klionsky, D. J., Munn, A. L., & Weisman, L. S. (1996). Multiple classes of yeast mutants are defective in vacuole partitioning yet target vacuole proteins correctly. Molecular Biology of the Cell, 7, 1375-1389. PubMed Link

Scott, S. V., Hefner-Gravink, A., Morano, K. A., Noda, T., Ohsumi, Y., & Klionsky, D. J. (1996). Cytoplasm-to-vacuole targeting and autophagy employ the same machinery to deliver proteins to the yeast vacuole. Proceedings of the National Academy of Sciences of the USA, 93, 12304-12308. PubMed Link

Harding, T. M., Morano, K. A., Scott, S. V., & Klionsky, D. J. (1995). Isolation and characterization of yeast mutants in the cytoplasm-to-vacuole protein targeting pathway. Journal of Cell Biology, 131, 591-602. PubMed Link

Scott, S. V., & Klionsky, D. J. (1995). In vitro reconstitution of cytoplasm-to-vacuole protein targeting in yeast. Journal of Cell Biology, 131, 1727-1735. PubMed Link

Destruelle, M., Holzer, H., & Klionsky, D. J. (1995). Isolation and characterization of a novel yeast gene, Ath1, that is required for vacuolar acid trehalase activity. Yeast, 11, 1015-1025. PubMed Link

Morano, K. A., & Klionsky, D. J. (1994). Differential effects of compartment deacidification on the targeting of membrane and soluble proteins to the vacuole in yeast. Journal of Cell Science, 107, 2813-2824. PubMed Link

Destruelle, M., Holzer, H., & Klionsky, D. J. (1994). Identification and characterization of a novel yeast gene - The Ygp1 gene product is a highly glycosylated secreted protein that is synthesized in response to nutrient limitation. Molecular and Cellular Biology, 14, 2740-2754. PubMed Link

Yaver, D. S., Nelson, H., Nelson, N., & Klionsky, D. J. (1993). Vacuolar ATPase mutants accumulate precursor proteins in a pre-vacuolar compartment. Journal of Biological Chemistry, 268, 10564-10572. PubMed Link

Klionsky, D. J., Nelson, H., & Nelson, N. (1992). Compartment acidification is required for efficient sorting of proteins to the vacuole in Saccharomyces cerevisiae. Journal of Biological Chemistry, 267, 3416-3422. PubMed Link

Klionsky, D. J., Cueva, R., & Yaver, D. S. (1992). Aminopeptidase I of Saccharomyces cerevisiae is localized to the vacuole independent of the secretory pathway. Journal of Cell Biology, 119, 287-299. PubMed Link

Klionsky, D. J., Nelson, H., Nelson, N., & Yaver, D. S. (1992). Mutations in the yeast vacuolar ATPase result in the mislocalization of vacuolar proteins. Journal of Experimental Biology, 172, 83-92. PubMed Link

Klionsky, D. J., & Emr, S. D. (1989). Membrane protein sorting - Biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO Journal, 8, 2241-2250. PubMed Link

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Articles (1982-1988)

Banta, L. M., Robinson, J. S., Klionsky, D. J., & Emr, S. D. (1988). Organelle assembly in yeast - Characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. Journal of Cell Biology, 107, 1369-1383. PubMed Link

Klionsky, D. J., Banta, L. M., & Emr, S. D. (1988). Intracellular sorting and processing of a yeast vacuolar hydrolase - Proteinase A propeptide contains vacuolar targeting information. Molecular and Cellular Biology, 8, 2105-2116. PubMed Link

Robinson, J. S., Klionsky, D. J., Banta, L. M., & Emr, S. D. (1988). Protein sorting in Saccharomyces cerevisiae: Isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Molecular and Cellular Biology, 8, 4936-4948. PubMed Link

Bedwell, D. M., Klionsky, D. J., & Emr, S. D. (1987). The yeast F1 ATPase beta-subunit precursor contains functionally redundant mitochondrial protein import information. Molecular and Cellular Biology, 7, 4038-4047. PubMed Link

Klionsky, D. J., & Simoni, R. D. (1985). Assembly of a functional F1 of the proton-translocating ATPase of Escherichia coli. Journal of Biological Chemistry, 260, 1200-1206. PubMed Link

Aris, J. P., Klionsky, D. J., & Simoni, R. D. (1985). The F0 subunits of the Escherichia coli F1F0-ATP synthase are sufficient to form a functional proton pore. Journal of Biological Chemistry, 260, 1207-1215. PubMed Link

Klionsky, D. J., Brusilow, W. S. A., & Simoni, R. D. (1984). In vivo evidence for the role of the epsilon subunit as an inhibitor of the proton-translocating ATPase of Escherichia coli. Journal of Bacteriology, 160, 1055-1060. PubMed Link

Humbert, R., Brusilow, W. S. A., Gunsalus, R. P., Klionsky, D. J., & Simoni, R. D. (1983). Escherichia coli mutants defective in the UNCH gene. Journal of Bacteriology, 153, 416-422. PubMed Link

Klionsky, D. J., Brusilow, W. S. A., & Simoni, R. D. (1983). Assembly of a functional F0 of the proton-translocating ATPase of Escherichia coli. Journal of Biological Chemistry, 258, 136-143. PubMed Link

Brusilow, W. S. A., Klionsky, D. J., & Simoni, R. D. (1982). Differential polypeptide synthesis of the proton-translocating ATPase of Escherichia coli. Journal of Bacteriology, 151, 1363-1371. PubMed Link

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Review Articles

Klionsky, D. J., & Kumar, A. (2006). A systems biology approach to learning autophagy. Autophagy, 2, 12-23.

Yorimitsu, T., & Klionsky, D. J. (2005). Autophagy: Molecular machinery for self-eating. Cell Death and Differentiation, 12 (Suppl. 2), 1542-1552.

Nair, U., & Klionsky, D. J. (2005). Molecular mechanisms and regulation of specific and nonspecific autophagy pathways in yeast. Journal of Biological Chemistry, 280, 41785-41788.

Klionsky, D. J. (2005). The molecular machinery of autophagy: Unanswered questions. Journal of Cell Science, 118, 7-18.

Levine, B., & Klionsky, D. J. (2004). Development by self-digestion: Molecular mechanisms and biological functions of autophagy. Developmental Cell, 6, 463-477.

Reggiori, F., Wang, C. W., Nair, U., Shintani, T., Abeliovich, H., & Klionsky, D. J. (2004). Early stages of the secretory pathway, but not endosomes, are required for Cvt vesicle and autophagosome assembly in Saccharomyces cerevisiae. Molecular Biology of the Cell, 15, 2189-2204.

Shintani, T., & Klionsky, D. J. (2004). Autophagy in health and disease: A double-edged sword. Science, 306, 990-995.

Huang, W. P., & Klionsky, D. J. (2002). Autophagy in yeast: A review of the molecular machinery. Cell Structure and Function, 27, 409-420.

Khalfan, W. A., & Klionsky, D. J. (2002). Molecular machinery required for autophagy and the cytoplasm to vacuole targeting (Cvt) pathway in S. cerevisiae. Current Opinion in Cell Biology, 14, 468-475.

Reggiori, F., & Klionsky, D. J. (2002). Autophagy in the eukaryotic cell. Eukaryotic cell, 1, 11-21.

Abeliovich, A., & Klionsky, D. J. (2001). Autophagy in yeast: Mechanistic insights and physiological function. Microbiology and Molecular Biology Reviews, 65, 463-479.

Stromhaug, P. E., & Klionsky, D. J. (2001). Approaching the molecular mechanism of autophagy. Traffic, 2, 524-531.

Kim, J., & Klionsky, D. J. (2000). Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells. Annual Review of Biochemistry, 69, 303-342.

Kim, J., Scott, S. V., & Klionsky, D. J. (2000). Alternative protein sorting pathways. International Review of Cytology - A Survey of Cell Biology, 198, 153-201.

Klionsky, D. J., & Emr, S. D. (2000). Cell biology - Autophagy as a regulated pathway of cellular degradation. Science, 290, 1717-1721.

Teter, S. A., & Klionsky, D. J. (2000). Transport of proteins to the yeast vacuole: Autophagy, cytoplasm-to-vacuole targeting, and role of the vacuole in degradation. Seminars in Cell & Developmental Biology, 11, 173-179.

Klionsky, D. J. (1998). Nonclassical protein sorting to the yeast vacuole. Journal of Biological Chemistry, 273, 10807-10810.

Klionsky, D. J. (1997). Protein transport from the cytoplasm into the vacuole. Journal of Membrane Biology, 157, 105-115.

Klionsky, D. J., Herman, P. K., & Emr, S. D. (1990). The fungal vacuole - Composition, function, and biogenesis. Microbiological Reviews, 54, 266-292.

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Editorial Material

Klionsky, D. J. (2006). Learning about autophagy. Autophagy, 2, 1.

Klionsky, D. J. (2006). What can we learn from trypanosomes? Autophagy, 2, 63-64.

Klionsky, D. J. (2006). How selective is autophagy? Autophagy, 2, 151-152.

Klionsky, D. J. (2006). Neurodegeneration - Good riddance to bad rubbish. Nature, 441, 819-820.

Klionsky, D. J., Meijer, A. J., Codogno, P., Neufeld, T. P., & Scott, R. C. (2005). Autophagy and p70S6 kinase. Autophagy, 1, 59-61.

Klionsky, D. J. (2005). The correct way to monitor autophagy in higher eukaryotes. Autophagy, 1, 65.

Klionsky, D. J. (2005). How to keep up in an expanding field: Addenda. Autophagy, 1, 129-130.

Klionsky, D. J. (2005). Autophagy. Current Biology, 15, R282-R283.

Klionsky, D. J. (2004). Cell Biology - Regulated self-cannibalism. Nature, 431, 31-32.

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Letters

Klionsky, D. J., Cregg, J. M., Dunn, W. A., Emr, S. D., Sakai, Y., Sandoval, I. V., Sibirny, A., Subramani, S., Thumm, M., Veenhuis, M., Ohsumi, Y. (2003). A unified nomenclature for yeast autophagy-related genes. Developmental Cell, 5, 539-545.

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Notes

Klionsky, D. J., & Emr, S. D. (1990). A new class of lysosomal vacuolar protein sorting signals. Journal of Biological Chemistry, 265, 5349-5352.

Klionsky, D. J., Skalnik, D. G., & Simoni, R. D. (1986). Differential translation of the genes encoding the proton-translocating ATPase of Escherichia coli. Journal of Biological Chemistry, 261, 8096-8099.

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