Garneau-Tsodikova Publications

Articles, Reviews, and Book Chapters (1998 - 2009) | Editorial Material (2008 - 2009)

Articles, Reviews, and Book Chapters (1998 - 2009)

30. Green, K.D., Chen, W., Houghton, J.L., Fridman, M., & Garneau-Tsodikova, S. (2009). Exploring the Substrate Promiscuity of Drug-modifying Enzymes for the Chemoenzymatic Generation of N-Acylated Aminoglycosides. ChemBioChem, (In Press). PubMed Link

29. Green, K.D., Fridman, M., & Garneau-Tsodikova, S. (2009). hChAT: a tool for the chemoenzymatic generation of potential acetyl/butyrylcholinesterase inhibitors. ChemBioChem, 10(13), 2191-2194. PubMed Link

28. Li, H.T., Ung, P.M.U., Zajkowski, J., Garneau-Tsodikova, S., & Sherman, D.H. (2009). Automated Genome Mining for Natural Products. BMC Bioinformatics, 10(1), 185-202. PubMed Link

27. Green, K.D., & Garneau-Tsodikova, S. (2009). Post-translational Modification of Proteins. (Book Chapter) Comprehensive Natural Products Chemistry II, (In Press).

26. Garneau-Tsodikova, S., Shkel, I.A., & Tsodikov, O.V. (2009). Exact and user-friendly kinetic analysis of the two-step rapid equilibrium Michaelis-Menten mechanism. Anal. Biochem., 387(2), 276-279. PubMed Link

25. McQuade, T.J., Shallop, A.D., Sheoran, A., DelProposto, J.E., Tsodikov, O.V., & Garneau-Tsodikova, S. (2009). A non-radioactive high-throughput assay for screening and characterization of adenylation domains for nonribosomal peptide combinatorial biosynthesis. Anal. Biochem., 386, 244-250. PubMed Link

24. Garneau-Tsodikova, S. (2008). Asymmetric Organic Synthesis with Enzymes (Book Review). J. Am. Chem. Soc., 130(32), 10829-10830. PubMed Link

23. Garneau-Tsodikova, S., & Thannickal, V.J. (2008). Protein Kinase Inhibitors in the Treatment of Pulmonary Fibrosis. Curr. Med. Chem., 15(25), 2632-2640. PubMed Link

22. Martin-Visscher, L.A., van Belkum, M.J., Garneau-Tsodikova, S., Whittal, R.M., Zhang, J., McMullen, L.M., & Vederas, J.C. (2008). Isolation and characterization of carnocyclin A, a novel circular bacteriocin produced by Carnobacterium maltaromaticum 307. Appl. Environ. Microbiol., 74(15), 4756-4763. PubMed Link

21. Sheoran, A., King, A., Velasco, A., Pero, J.M., & Garneau-Tsodikova, S. (2008). Characterization of TioF, a tryptophan 2,3-dioxygenase involved in 3-hydroxyquinaldic acid formation during thiocoraline biosynthesis. Molecular Biosystems, 4(6), 622-628. PubMed Link

20. Fridman, M., Balibar, C.J., Lupoli, T., Kahne, D., Walsh, C.T., & Garneau-Tsodikova, S. (2007). Chemoenzymatic Formation of Novel Aminocoumarin Antibiotics by the Enzymes CouN1 and CouN7. Biochemistry, 46, 8462-8471. PubMed Link

19. Balibar, C.J., Garneau-Tsodikova, S. , & Walsh, C.T. (2007). Covalent CouN7 Enzyme Intermediate for Acyl Group Shuttling in Aminocoumarin Biosynthesis. Chemistry & Biology, 14, 679-690. PubMed Link

18. Garneau-Tsodikova, S. , Dorrestein, P.C., Kelleher, N.L., & Walsh, C.T. (2006). Protein assembly line components in prodigiosin biosynthesis: Characterization of PigA,G,H,I,J. Journal of the American Chemical Society, 128, 12600-12601. PubMed Link

17. Vaillancourt, F.H., Yeh, E., Vosburg, D.A., Garneau-Tsodikova, S. , & Walsh, C.T. (2006). Nature's Inventory of Halogenation Catalysts: Oxidative Strategies Predominate. Chemical Reviews, 106, 3364-3378. PubMed Link

16. Ueki, M., Galonic, D.P., Vaillancourt, F.H., Garneau-Tsodikova, S. , Yeh, E., Vosburg, D.A., Schroeder, F.C., Osada, H., & Walsh, C.T. (2006). Enzymatic Generation of the Antimetabolite γ,γ-Dichloroaminobutyrate by NRPS and Mononuclear Iron Halogenase Action in a Streptomycete. Chemistry & Biology, 13, 1183-1191. PubMed Link

15. Dorrestein, P.C., Bumpus, S.B., Calderone, C.C., Garneau-Tsodikova. S., Aron, Z.D., Straight, P.D., Kolter, R., Walsh, C.T., & Kelleher, N.L. (2006). Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry, 45, 12756-12766. PubMed Link

14. Walsh, C.T., Garneau-Tsodikova, S., and Howard-Jones, A.R. (2006). Biological Formation of Pyrroles: Nature's Logic and Enzymatic Machinery. Natural Products Reports. 23, 517-531. PubMed Link

13. Dorrestein, P.C., Blackhall, J., Straight, P.D., Fischbach, M.A., Garneau-Tsodikova, S., Edwards, D.J., McLaughlin, S., Lin, M., Gerwick, W.H., Kolter, R., Walsh, C.T., & Kelleher, N.L. (2006). Activity screening of carrier domains within nonribosomal peptide synthetases using complex substrate mixtures and large molecule mass spectrometry. Biochemistry, 45, 1537-1546. PubMed Link

12. Garneau-Tsodikova, S., Stapon, A., Kahne, D., & Walsh, C.T. (2006). Installation of the Pyrrolyl-2-carboxyl pharmacophore by CouN1 and CouN7 in the late biosynthetic steps of the aminocoumarin antibiotics clorobiocin and coumermycin A1. Biochemistry, 45, 8568-8578. PubMed Link

11. Garneau, S., Dorrestein, P.C., Kelleher, N.L., & Walsh, C.T. (2005). Characterization of the formation of the pyrrole moiety during clorobiocin and coumermycin A(1) biosynthesis. Biochemistry, 44, 2770-2780. PubMed Link

10. Walsh, C.T., Garneau-Tsodikova, S., & Gatto, G.J. (2005). Protein posttranslational modifications: The chemistry of proteome diversifications. Angewandte Chemie - International Edition, 44, 7342-7372. PubMed Link

9. Yeh, E., Garneau, S., & Walsh, C.T. (2005). Robust in vitroactivity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotrypthophan during rebeccamycin biosynthesis. Proceedings of the National Academy of Sciences of the USA, 102, 3960-3965. PubMed Link

8. Dorrestein, P.C., Yeh, E., Garneau-Tsodikova, S., Kelleher, N.L., & Walsh, C.T. (2005). Dichlorination of a pyrrolyl-S-carrier protein by FADH(2)-dependent halogenase PltA during pyoluteorin biosynthesis. Proceedings of the National Academy of Sciences of the USA, 102, 13843-13848. PubMed Link

7. Garneau, S., Qiao, L., Chen, L., Walker, S., & Vederas, J.C. (2004). Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. Bioorganic & Medicinal Chemistry, 12, 6473-6494. PubMed Link

6. Liu, F., Garneau, S., & Walsh, C.T. (2004). Hybrid nonribosomal peptide-polyketide interfaces in epothilone biosynthesis: Minimal requirements at N and C termini of EpoB for elongation. Chemistry & Biology, 11, 1533-1542. PubMed Link

5. Garneau, S., Ference, C.A., van Belkum, M.J., Stiles, M.E., & Vederas, J.C. (2003). Purification and characterization of brochocin A and brochochin B(10-43), a functional fragment generated by heterologous expression in Carnobacterium piscicola. Applied and Environmental Microbiology, 69, 1352-1358. PubMed Link

4. Mau, C.J.D., Garneau, S., Scholte, A.A., van Fleet, J.E., Vederas, J.C., & Cornish, K. (2003). Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase. European Journal of Biochemistry, 270, 3939-3945. PubMed Link

3. Garneau, S., Martin, N.I., & Vederas, J.C. (2002). Two-peptide bacteriocins produced by lactic acid bacteria. Biochimie, 84, 577-592. PubMed Link

2. Garneau, S., Rondeau, P., Bazuin, C.G., & Ritcey, A.M. (2000). Stabilisation of spread monolayers of an amine-functionalised biphenyl mesogen by association with a carboxymethyl cellulose salt. Macromolecular Chemistry and Physics, 201, 2535-2541.

1. Desjardins, M., Garneau, S., Desgagnes, J., Lacoste, L., Yang, F., Lapointe, J., & Chenevert, R. (1998). Glutamyl adenylate analogues are inhibitors of glutamyl-tRNA synthetase. Bioorganic Chemistry, 26, 1-13.

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Editorial Material (2008 - 2009)

1. Garneau-Tsodikova, S. (2008). Asymmetric Organic Synthesis with Enzymes (Book Review). J. Am. Chem. Soc., 130(32), 10829-10830. PubMed Link

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