October 5, 2009 - Chemical & Engineering News - New chemical tools are poised to help scientists explore the roles oxidized cysteine residues might play in biology.
Sept 7, 2009 - LSI faculty member Kate S. Carroll and research partners have developed a new method to monitor early signs of oxidative stress in cancer that depends on detecting sulfenic acid in proteins. Being able to monitor a marker of oxidative stress that is associated with the activation of tumor cell growth pathways, particularly at an early stage, and then tailor treatments accordingly would allow for more targeted studies and might improve the odds of success with antioxidants and pro-oxidants. The method and the research behind it are described in a paper scheduled for online publication in the Proceedings of the National Academy of Sciences during the week of Sept. 7.
September 3, 2009 - LSI faculty member Kate S. Carroll and research partners are reporting the development of a powerful new probe for identifying proteins affected by a chemical chemical process important in aging and disease. The probe works like a GPS or navigation system for finding these proteins in cells. It could lead to new insights into disease processes and identify new targets for disease treatments. Their study is scheduled for the Sept. 18. issue of ACS Chemical Biology.
March 26, 2009 - LSI faculty member Kate Carroll was recently interviewed for a Cell Press podcast about her study that was recently published in Chemistry & Biology. In this interview, she discusses an intricate molecular interaction that underpins the oxidative stress response in yeast. Cell Press publishes monthly podcasts featuring interviews with leading scientists from around the world. For more information:
March 17, 2008 - LSI faculty member Kate S. Carroll and research partners have published a new paper titled "A chemical approach for detecting sulfenic acid-modified proteins in living cells" in the Emerging Investigator's Issue of Molecular Biosystems. Carroll's group has developed a probe that could help researchers study oxidative stress in living cells. Oxidative stress has been implicated in phenomena as diverse as aging, cancer, neurodegeneration, and diabetes.
October 2006 - Kate Carroll and colleagues have founded a research website entitled Cells and Sulfur: Strategies for Using a Versatile Element" as part of the New York Academy of Sciences.
