Center for Structural Biology

Collaboratory for X-ray Crystallography, Crystallization and Protein Engineering

From Clone to Structure

The Center for Structural Biology (CSB) is a comprehensive structural biology resource for researchers at the University of Michigan and surrounding area.

The Center includes:

• High-Throughput Protein Laboratory for protein engineering
• Protein Purification Facilities for small- and large-scale protein production
• Macromolecular Crystallization & Crystallography Laboratories for solving crystal structures of biological molecules
• X-ray Facility with access to high energy synchotron radiation

Staff scientists in the Center collaborate or consult with researchers who use the Center. The Center has a programmatic collaboration with the Center for Chemical Genomics (CCG) in which structures can be determined of target proteins in complex with compounds identified in high-throughput screens in the CCG. Leadership of the Center includes Dr. Janet Smith, Director; Dr. Jeanne Stuckey, Managing Director of Protein Purification, Macromolecular Crystallization & Crystallography and X-ray; and Dr. Clay Brown, Scientific Director of the High-Throughput Protein Lab.

If you would like to receive e-mail announcements about CSB events, please subscribe by sending an e-mail to Vashni Santee.