Funding

HTS Grant Opportunities

• Assay Development for High Throughput Molecular Screening (R21) (PAR-08-024) NIH Roadmap Initiatives Application Receipt/Submission Date(s): November 20, 2008; March 20, 2009; November 20, 2009; March 20, 2010
• Development of Assays for High-Throughput Drug Screening (R01)
  standard R01 dates apply, expires May 2010
• Solicitation of HTS Assays for MLSCNs (R03)
  application due Jun. 26, 2007, expires Oct. 2007
• Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders (R21)
  next due date Jun. 16, 2007, expires Jul. 2, 2009

Liquid Handling Robotics:

• Beckman Biomek FX
• 96-well liquid transfer head
• Multidrop 96-384 well plate fillers
• Bio-Tek ELx405 Plate Washer
• Detection equipment
• Pherastar high-speed, multifunction plate reader
• Detection capabilities including 96-, 384-, and 1536-well: absorbance, fluorescence, fluorescence polarization, time-resolved fluorescence, time-resolved FRET, and luminescence

Informatics:

• Web database using Oracle
  
  Functionality:
  Relational database of compounds, plate inventory, results
  Results browsing or searching
  Comparison of results among different screens
  Structure similarity searches for hits
• Tripos Benchware HTS Dataminer with HTS module
  Chemical spreadsheet, Chemical structure clustering, SAR Analysis