Research and Publications
History of small molecule and siRNA screening capatilities | Information on screening materials & technologies | Research Highlights
CCG-Related Publications
Publications Archive 2007-2011
Recent Publications:
Reilly, SM et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nature Medicine (2013) 19, 313-321. doi:10.1038/nm.3082
Larsen, MJ et al. Functional Expression and Characterization of the C. elegans G-protein-coupled FLP-2 Receptor (T19F4.1) in Mammalian Cells and Yeast. Intl J Parasit: Drugs and Drug Resistance (2013) 3, 1-7.
Warner, N et al. A Genome-Wide siRNA Screen Reveals Positive and Negative Regulators of the NOD2 and NF-kB Signaling Pathways. Sci Signal, 2013 Jan 15;6(258):rs3. doi: 10.1126/scisignal.2003305.
PubMed Link
Majmudar CY, et al. Sekikaic acid and lobaric acid target a dynamic interface of the coactivator CBP/p300. Angew Chem Int Ed Engl, 2012 Nov 5;51(45):11258-62. doi: 10.1002/anie.201206815. Epub 2012 Oct 8.
PubMed Link
Jacob RT, et al. MScreen: an integrated compound management and high-throughput screening data storage and analysis system. J Biomol Screen, 2012 Sep;17(8):1080-1087. Epub 2012 June 15
PubMed Link
Seguin SP, et al. A screen for modulators of large T antigen's ATPase activity uncovers novel inhibitors of Simian Virus 40 and BK virus replication. Antiviral Res, 2012 Aug 7;96(1):70-81. [Epub ahead of print]
Sjogren B, et al. Cardiotonic steroids stabilize RGS2 protein levels. Molecular Pharmacology, doi: 10.1124/mol.112.079293, June 13, 2012.
Wang Y, et al. (2012) Small molecule screening identifies regulators of the transcription factor. DeltaFosB. ACS Chem Neurosci, doi: 10.1021/cn3000235, March 29, 2012.
Green KD, et al. (2012) Identification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosis. ChemMedChem Jan 2;7(1):73-77. doi: 10.1002/cmdc.201100332. Epub 2011 Sep 5
PubMed Link
Sun H, et al. (2012) Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. PNAS Feb 28;109(9);3469-74 Epub 2012 Feb 13
PubMed Link
Grembecka J, et al. (2012) Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nat Chem Biol. Jan 29;8(3):277-84. doi: 10.1038/nchembio. 773.
PubMedLink
Other Publications of Interest:
Delude C, (2012) Conquering Pain and Infection with Drugs from Nature's Medicine Cabinet. Breakthroughs in Bioscience, Federation of American Societies for Experimental Biology (FASEB).
Link to article.
Hughes JP, Rees S, Kalindjian SB, Philpott KL (2011) Principles of early drug discovery. Br J Pharmacol. March;162(6):1239-1249.
PubMedLink
