Research and Publications
History of small molecule and siRNA screening capatilities | Information on screening materials & technologies |
CCG-Related Publications
Publications Archive 2007-2010
Recent Publications:
Sun H, et al. (2012) Inhibitor of streptokinase gene expression improves survival after group A streptococcus infection in mice. PNAS Feb 28;109(9);3469-74 Epub 2012 Feb 13
PubMed Link
Grembecka J, et al. (2012) Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. Nat Chem Biol. Jan 29;8(3):277-84. doi: 10.1038/nchembio. 773.
PubMedLink
Fribley AM, et al. (2011) Complementary cell-based high-throughput screens identify novel modulators of the unfolded protein response. J Biomol Screen Sep;16(8):825-35.
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Blazer LL, et al. (2011) A nanomolar-potency small molecule inhibitor of regulator of G-protein signaling proteins. Biochemistry Apr19;50(15):3181-92.
PubMedLink
Bainor A et al. (2011) Bicinchoninic acid (BCA) assay in low volume. Anal Biochem Mar15;410(2):310-2.
PubMedLink
Chang L, et al. (2011) Chemical screens against a reconstituted multiprotein complex: myricetin blocks DnaJ regulation of DnaK through an allosteric mechanisms. Chem Biol Feb 25;18(2):210-21.
PubMedLink
Bulfer SL et al. (2011) Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase. Anal Biochem Mar 1;410(1):133-40.
PubMedLink
Monroe SC et al. (2011) MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia. Exp Hematol Jan;39(1):77-86.e1-5
PubMedLink
Other Publications of Interest:
Hughes JP, Rees S, Kalindjian SB, Philpott KL (2011) Principles of early drug discovery. Br J Pharmacol. March;162(6):1239-1249.
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